Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Question
Chapter 18, Problem 27CONQ
Summary Introduction
To review:
The roleof human immunodeficiency virus protease in the maturation of human immunodeficiency virus.
Introduction:
Human immunodeficiency virus (HIV) is a virus which belongs to the genusLentivirus. This family of virus comes under the family retroviradae. HIV infection leads toAIDS (acquired immunodeficiency syndrome). AIDSrefers to the spectrum of diseases in which many diseasesoccur due to a weak immune system. HIV virus directlyaffects the immune system of the individual.
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Explain the role of RNase H (a component of reverse transcriptase)during the synthesis of HIV DNA.
Describe the role of the Gag polyprotein during the assembly of HIV components at the host-cell plasma membrane.
Describe the process of reverse transcription of HIV RNA.
Chapter 18 Solutions
Genetics: Analysis and Principles
Ch. 18.1 - 1. What is a common feature found in all viruses?...Ch. 18.1 - 2. Viral genomes can be
a. DNA or RNA.
b....Ch. 18.2 - Prob. 1COMQCh. 18.2 - Prob. 2COMQCh. 18.3 - A mutation in phage results in 10-fold greater...Ch. 18.3 - 2. The cl gene that encodes the λ repressor has...Ch. 18.4 - A viral protein that is needed to make HIV DNA is...Ch. 18.4 - Prob. 2COMQCh. 18.4 - After HIV components are made, what is the correct...Ch. 18 - 1. Discuss why viruses are considered nonliving.
Ch. 18 - What structural features are common to all...Ch. 18 - 3. What are the similarities and differences among...Ch. 18 - Prob. 4CONQCh. 18 - Prob. 5CONQCh. 18 - Prob. 6CONQCh. 18 - Prob. 7CONQCh. 18 - Prob. 8CONQCh. 18 - Prob. 9CONQCh. 18 - Prob. 10CONQCh. 18 - 11. What is a prophage, a provirus, and an...Ch. 18 - Prob. 12CONQCh. 18 - Prob. 13CONQCh. 18 - 14. With regard to promoting the lytic or...Ch. 18 - 15. How do therepressor and the cro protein affect...Ch. 18 - Prob. 16CONQCh. 18 - Figure 18.11 shows a genetic switch that controls...Ch. 18 - Prob. 18CONQCh. 18 - Prob. 19CONQCh. 18 - Explain the role of RNase H (a component of...Ch. 18 - Prob. 21CONQCh. 18 - Prob. 22CONQCh. 18 - Prob. 23CONQCh. 18 - 24. Compare and contrast the roles of fully...Ch. 18 - 25. Describe the role of the Gag polyprotein...Ch. 18 - Prob. 26CONQCh. 18 - Prob. 27CONQCh. 18 - 1. Discuss how researchers determined that TMV is...Ch. 18 - Prob. 2EQCh. 18 - What is a reconstituted virus?Ch. 18 - Following the infection of healthy tobacco leaves...Ch. 18 - Prob. 5EQCh. 18 - Prob. 6EQCh. 18 - A researcher identified a mutation in PR of phage ...Ch. 18 - Experimentally, when an E. coli bacterium already...Ch. 18 - 9. A bacterium is exposed to a drug that inhibits...Ch. 18 - This question combines your knowledge of bacterial...Ch. 18 - Prob. 1QSDCCh. 18 - 2. Certain environmental conditions such as...Ch. 18 - 3. Browse the Internet to determine the drugs that...
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Similar questions
- present the chemical mechanism of the HIV protease. Discuss the mode of action of some inhibitors of this enzyme.arrow_forwardWhich form of HIV RNA, fully spliced, incompletely spiced, or unspliced, is needed during the early stage of the synthesis of HIV components?arrow_forwardHow is AZT a competitive inhibitor of HIV reverse transcriptase?arrow_forward
- Tat and Rev proteins are required for HIV replication. What are their roles and why are they essential to the virus?arrow_forwardWhy is HIV protease a good target for anti-HIV therapy and drug discovery?arrow_forwardRetroviruses, like the HIV, contain an enzyme called reverse transcriptase. Explain the flow of genetic information in HIV.arrow_forward
- Describe the reason behind the occurrence of phage growth and release by the mating with the non-lysogenic recipient, but not with the infection by a lysogenic recipient.arrow_forwardDescribe two mechanisms a virus might use to prevent the induction of apoptosis in an infected cell.arrow_forwardHow can one confirm/investigate the type of inhibition exerted by azt on the hiv reverse transcriptase enzyme?arrow_forward
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