Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 15, Problem 33RA
Why are antibodies composed of different chains, and why are there several genes that encode the parts of a particular antibody molecule? What would happen if each antibody were coded for by only one gene?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
How are antibodies unique? Please discuss the structure of an antibody. What are the V and C regions? Discuss how the few hundred genes involved are capable of making endless amounts of antibodies. Besides medical treatment what is another way antibodies can be used?
What is the reason behind antibody diversity?
Name the two types of antibody light chains.
Chapter 15 Solutions
Human Physiology
Ch. 15 - List the phagocytic cells found in blood and...Ch. 15 - Prob. 1bCPCh. 15 - Prob. 2aCPCh. 15 - Prob. 2bCPCh. 15 - Prob. 2cCPCh. 15 - Prob. 3CPCh. 15 - Prob. 4aCPCh. 15 - Prob. 4bCPCh. 15 - Prob. 5CPCh. 15 - Prob. 6aCP
Ch. 15 - Prob. 6bCPCh. 15 - Define the term histocompatibility antigens and...Ch. 15 - Prob. 7bCPCh. 15 - Prob. 8aCPCh. 15 - Prob. 8bCPCh. 15 - Prob. 8cCPCh. 15 - Prob. 8dCPCh. 15 - Prob. 9CPCh. 15 - Prob. 10aCPCh. 15 - Prob. 10bCPCh. 15 - Prob. 10cCPCh. 15 - Prob. 11CPCh. 15 - Prob. 12aCPCh. 15 - Prob. 12bCPCh. 15 - Which of these offers a nonspecific defense...Ch. 15 - Prob. 2RACh. 15 - Prob. 3RACh. 15 - Prob. 4RACh. 15 - Prob. 5RACh. 15 - Prob. 6RACh. 15 - Prob. 7RACh. 15 - Mast cell secretion during an immediate...Ch. 15 - Prob. 9RACh. 15 - Which of these cell types aids the activation of T...Ch. 15 - Prob. 11RACh. 15 - Delayed hypersensitivity is mediated by...Ch. 15 - Active immunity may be produced by...Ch. 15 - Which of these statements about class-2 MHC...Ch. 15 - Prob. 15RACh. 15 - Prob. 16RACh. 15 - Prob. 17RACh. 15 - Which of these statements about gamma interferon...Ch. 15 - Explain how antibodies help to destroy invading...Ch. 15 - Identify the different types of interferons and...Ch. 15 - Distinguish between the class-I and class-2 MHC...Ch. 15 - Prob. 22RACh. 15 - Prob. 23RACh. 15 - Describe how plasma cells attack antigens and how...Ch. 15 - Explain how tolerance to self-antigens may be...Ch. 15 - Use the clonal selection theory to explain how...Ch. 15 - Prob. 27RACh. 15 - Distinguish between immediate and delayed...Ch. 15 - Describe regulatory T lymphocytes and their...Ch. 15 - Prob. 30RACh. 15 - The specific T lymphocyte immune response is...Ch. 15 - Lizards are cold-blooded; their body temperature...Ch. 15 - Why are antibodies composed of different chains,...Ch. 15 - As a scientist trying to cure allergy, you are...Ch. 15 - The part of the placenta that invades the mother's...Ch. 15 - Describe the antigen-dependent and...Ch. 15 - People with peanut allergies could go into...Ch. 15 - Identify some immunologically privileged sites in...Ch. 15 - Use figure 15.6 to answer the following questions...Ch. 15 - Use figure 15.6 to answer the following questions...Ch. 15 - Prob. 41RACh. 15 - Prob. 42RA
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What is the variable region of an antibody? The hypervariable or complementarity-determining region? The constant region?arrow_forwardWhat is the basic structure of the antibody molecule?arrow_forwardThe Fab regions of an antibody are made of which protein chain? A) a heavy chain containing only constant regions B) a light chain containing variable and constant regions C) a heavy chain containing variable and constant regions D) both a light chain and a heavy chain containing variable and constant regions E) both a light chain containing variable and constant regions and a heavy chain containing only constant regionsarrow_forward
- How is the part of an antibody molecule that interacts with an antigen similar to the active site of an enzyme? How is it different?arrow_forwardDiagram the structure of an antibody. What parts bind toantigens? Why does each antibody bind only to one or afew specific antigens?arrow_forwardThe ends of each heavy chain and light chain in an immunoglobulin make up the antigen-binding sites. The end of one of these chains is shown here. Biochemists tend to classify protein structures into four groups: mostly alpha, mostly beta, mixed alpha and beta, or neither alpha nor beta. Based on the model shown here, how would you classify this part of the immunoglobulin protein? The loopy polypeptide segments at the very top of the structure shown are the segments that actually contact the antigen. Would you expect these binding segments to be rigid or flexible?arrow_forward
- Before the mechanism for generating antibody diversity had been established, a mechanism based on protein folding around an antigen was proposed, primarily by Linus Pauling. In this model, antibodies that had different specificities had the same amino acid sequence but were folded in different ways. Propose a test of this model.arrow_forwardDraw a schematic diagram of a typical IgG molecule and label each of the following parts: H chains, L chains, intrachain disulfide bonds, hinge, Fab, Fc, and all the domains. Indicate which domains are involved in antigen binding.arrow_forwardWhat is Natural antibodies?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Immune System and Immune Response Animation; Author: Medical Sciences Animations;https://www.youtube.com/watch?v=JDdbUBXPKc4;License: Standard YouTube License, CC-BY
Immune response: summary; Author: Dr Bhavsar Biology;https://www.youtube.com/watch?v=ADANgHkX4OY;License: Standard Youtube License