Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12, Problem 8MCQ
Which of the following modes of action would be most selectively toxic?
- a. interrupting ribosomal function
- b. dissolving the cell membrane
- c. preventing cell wall synthesis
- d. inhibiting
DNA replication
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Students have asked these similar questions
Match the following drug targets with the type of antibiotic that uses them (answers may be used more than once or not at all).
a. Cell wall
b.Cell membrane
c. Protein synthesis (Transcription/Translation)
d. Metabolic Pathway
e. Nucleic Acid synthesis
Chloramphenicol
Clindamycin
Erythromycin
Doxycycline
Sulfonamides
Answer these multiple-choice questions as well. Please give just the answer and no explanation.
1. Which is not true of virus capsids?a. They surround and protect viral nucleic acidb. Always icosahedral in shapec. Remain outside of host bacterial cells while the nucleic acid is injected into the bacterial
celld. Enters host animal cells together with the nucleic acid
e. Made up of protein subunits called capsomeres
2. All viruses have:
a. DNA
b. RNAc. Envelopesd. Glycoprotein spikes
e. Host specificity
3. Use the following to select the sequence of events during replication of DNA viruses in animal
cells:1 = replication of viral nucleic acid2 = adsorption3…
Which of the following compounds represents a peptidoglycan specific antibiotic ?
A. tetracycline
B. chloramphenicol
C. penicillin
D. aspirin
Which of the following is not used as an antiseptic?
A. Chlorhexidine
B. Phenol
C. Iodophor
D. Hydrogen Peroxide
Chapter 12 Solutions
Microbiology: A Systems Approach
Ch. 12.1 - State the main goal of antimicrobial treatment.Ch. 12.1 - Identify sources of the most commonly used...Ch. 12.1 - Summarize two methods for testing antimicrobial...Ch. 12.1 - Prob. 4AYPCh. 12.2 - Prob. 5AYPCh. 12.2 - Describe the five major targets of antimicrobial...Ch. 12.2 - Identify which categories of drugs are most...Ch. 12.3 - Prob. 8AYPCh. 12.3 - Trace the development of penicillin...Ch. 12.3 - Prob. 10AYP
Ch. 12.3 - Prob. 11AYPCh. 12.3 - Prob. 12AYPCh. 12.3 - Prob. 13AYPCh. 12.3 - Identify the cellular target of quinolones, and...Ch. 12.3 - Prob. 15AYPCh. 12.3 - Prob. 16AYPCh. 12.3 - Prob. 17AYPCh. 12.3 - Prob. 18AYPCh. 12.3 - Describe two major modes of action of antiviral...Ch. 12.4 - Prob. 20AYPCh. 12.4 - Prob. 21AYPCh. 12.4 - Discuss at least three novel antimicrobial...Ch. 12.5 - Distinguish between drug toxicity and allergic...Ch. 12.5 - Prob. 24AYPCh. 12 - Prob. 1MCQCh. 12 - Prob. 2MCQCh. 12 - Prob. 3MCQCh. 12 - Microbial resistance to drugs is acquired through...Ch. 12 - Prob. 5MCQCh. 12 - Prob. 6MCQCh. 12 - Prob. 7MCQCh. 12 - Which of the following modes of action would be...Ch. 12 - Prob. 9MCQCh. 12 - Prob. 10MCQCh. 12 - Prob. 11TFCh. 12 - Prob. 12TFCh. 12 - Biofilms are difficult to treat and do not always...Ch. 12 - Prob. 14TFCh. 12 - Prob. 15TFCh. 12 - Construct a paragraph describing the...Ch. 12 - Prob. 2CTQCh. 12 - Antibiotic-resistance genes, as well as other...Ch. 12 - Prob. 4CTQCh. 12 - What is the significance of the bottom row in...Ch. 12 - Figure 12.5. Where could penicillinase affect each...Ch. 12 - From chapter 6, process figure 6.14a. Describe as...Ch. 12 - Prob. 1CM
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- Define the following terms: a. turnover b. cyt P450 c. detoxication d. detoxification e. epoxidearrow_forwardThe type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardWhich of the following is NOT a property of an antimicrobial agent? a. Must have a known concentration over a period of time required to eliminate a pathogen b. all choices are correct c. must be selectively toxic d. Must have a favorable chemotherapeutic indexarrow_forward
- Select all of the pathways that can lead to pore production in a microbial cell. A. Alternative B. Lectin C. Classicalarrow_forwardA compound synthesized by bacteria or fungi that destroys or inhibitsthe growth of other microbes is a(n)a. synthetic drug b. antibiotic c. antimicrobial drug d. competitive inhibitorarrow_forwardWhich ONE of the following best describes ciprofloxacin? Select one: A. Active against Streptococcus pneumoniae B. An inhibitor of RNA synthesis C. An antimicrobial prodrug D. A natural product produced by Streptomyces spp. E. Subject to new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effectsarrow_forward
- An antiviral drug that is a guianine analog would have an antiviral mode of action that: a) blocks penetration b) blocks DNA replication c) inhibits peptidoglycan cross linking d) blocks maturation e) bonds to ergosterol in the cell membranearrow_forwardAn example of an agent that has lowers the surface tension of cells isarrow_forwarda) Biofilm is: a. a complex established community of microorganisms on solid surfaces b. is a layer of millions of identical bacteria on solid surfaces c. is a layer of compounds released from the tissue as a protection against pathogenic microorganisms d. All of these are correct b) Capsule formation is associated with the virulence of pathogenic bacteria. Why? Select all that apply. a. They are sticky and attach better b. They can escape phagocytosis c. The capsule makes them grow/multiply faster d. They kill immune cellsarrow_forward
- 1.) Which of the following are criteria for antibiotics? ( Select all that apple) A. Kill viruses B. Chemical substances produced by a microscope C. Effective in small doses D. Stops the growth or kills other microorganisms. 2) which antibiotic inhibits protein synthesis? ( select all that apply) A. Gentamicin B. Amoxicillin C. Erythromycin D. Tetracyclinearrow_forwardWhat is the mechanism of action of the antimicrobial used to treat patients with Fungal infections * a. Inhibits ergosterol synthesis b. Inhibits glucan synthesis c. Inhibits protein synthesis d. Inhibits nucleic acid synthesisarrow_forwardAntibiotics are very important in modern medical treatment: a) How is Giardia, a eukaryotic pathogenic parasite, affected by penicillin? Explain your answer. b) Is it beneficial to use sulfonamide and trimethoprim at the same time to treat an infection? Motivate your answer.arrow_forward
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