Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 12, Problem 13TF
Biofilms are difficult to treat and do not always respond to antibiotics.
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Chapter 12 Solutions
Microbiology: A Systems Approach
Ch. 12.1 - State the main goal of antimicrobial treatment.Ch. 12.1 - Identify sources of the most commonly used...Ch. 12.1 - Summarize two methods for testing antimicrobial...Ch. 12.1 - Prob. 4AYPCh. 12.2 - Prob. 5AYPCh. 12.2 - Describe the five major targets of antimicrobial...Ch. 12.2 - Identify which categories of drugs are most...Ch. 12.3 - Prob. 8AYPCh. 12.3 - Trace the development of penicillin...Ch. 12.3 - Prob. 10AYP
Ch. 12.3 - Prob. 11AYPCh. 12.3 - Prob. 12AYPCh. 12.3 - Prob. 13AYPCh. 12.3 - Identify the cellular target of quinolones, and...Ch. 12.3 - Prob. 15AYPCh. 12.3 - Prob. 16AYPCh. 12.3 - Prob. 17AYPCh. 12.3 - Prob. 18AYPCh. 12.3 - Describe two major modes of action of antiviral...Ch. 12.4 - Prob. 20AYPCh. 12.4 - Prob. 21AYPCh. 12.4 - Discuss at least three novel antimicrobial...Ch. 12.5 - Distinguish between drug toxicity and allergic...Ch. 12.5 - Prob. 24AYPCh. 12 - Prob. 1MCQCh. 12 - Prob. 2MCQCh. 12 - Prob. 3MCQCh. 12 - Microbial resistance to drugs is acquired through...Ch. 12 - Prob. 5MCQCh. 12 - Prob. 6MCQCh. 12 - Prob. 7MCQCh. 12 - Which of the following modes of action would be...Ch. 12 - Prob. 9MCQCh. 12 - Prob. 10MCQCh. 12 - Prob. 11TFCh. 12 - Prob. 12TFCh. 12 - Biofilms are difficult to treat and do not always...Ch. 12 - Prob. 14TFCh. 12 - Prob. 15TFCh. 12 - Construct a paragraph describing the...Ch. 12 - Prob. 2CTQCh. 12 - Antibiotic-resistance genes, as well as other...Ch. 12 - Prob. 4CTQCh. 12 - What is the significance of the bottom row in...Ch. 12 - Figure 12.5. Where could penicillinase affect each...Ch. 12 - From chapter 6, process figure 6.14a. Describe as...Ch. 12 - Prob. 1CM
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- Biofilms represent an important environmental niche. A) How does growth on a surface differ from growth in a suspended laboratory culture? (In other words: How do biofilm-forming cultures differ from planktonic cultures) B) Describe the stages of biofilm development including cellular and extracellular components?arrow_forwardWhy is biofilm development in catheters (tubes that can be inserted into a body cavity, duct or vessel which allow drainage or injection of fluids) such a dangerous source of infection in hospitals?arrow_forwardDiseases that involve biofilm-producing bacteria are of serious concern. They are not as easily treated compared with those involving free-floating (or planktonic) bacteria. Explain three reasons why biofilm formers are more pathogenic. Brian goes to the hospital after not feeling well for a week. He has a fever of 38 °C (100.4 °F) and complains of nausea and a constant migraine. Distinguish between the signs and symptoms of disease in Brian’s case.arrow_forward
- Describe a detrimental and a beneficial effect of biofilms.arrow_forwardWhich of the following is not true about biofilms a) are caused by many Gram positive and Gram negative bacteria as well as algae and fungi b) are highly contagious c) are hard to treat due to impermeability to drugsarrow_forwardBiofilms are often formed on artificial surfaces in the human body. During medical procedures, when artificial joints, intravenous catheters, urinary catheters are placed and injections are made, commensals/mutualists may be introduced into new sites in the body and there they may form biofilms. Which statement below is NOT a reason to explain why such bacteria living in biofilms are so difficult to eliminate? O layers of biofilm prevent phagocytes from killing bacteria O layers of biofilm acts a a diffusion barrier against antibiotics O biofilm stimulates bacteria to grow continually in the log/exponential phase of growth O layers of biofilm acts a a diffusion barrier against antibodies/immunoglobulins O bacteria often in stationary phase of growtharrow_forward
- Biofilms represent an important environmental niche. A) How does growth on a surface differ from growth in a suspended laboratory culture? (In other words: How do biofilm-forming cultures differ from planktonic cultures) B) Describe the stages of biofilm development including cellular and extracellular components? C) What processes regulate might regulate biofilm formation? Is quorum sensing involved and if so, how common is it? D) Why would biofilms promote the formation of genetic variants? What are the mechanisms by which this might occur? These questions are all related.arrow_forwardWhich of the following are ways in which forming a biofilm can make a bacterial infection more difficult to fight off or treat? Choose all that apply. Bacteria in biofilms can cause the immune system to attack human cells Bacteria in biofilms can have increased antibiotic resistance Bacteria in biofilms can no longer move Bacteria in biofilms are difficult for white blood cells to engulfarrow_forwardDescribe the basic process of biofilm formation.arrow_forward
- Describe why bacterial biofilms can be a threat to human health.arrow_forwardBacterial growth depends on many environmental factors, including the temperature of the environment. Since microbes can survive in a certain range of temperatures and will thrive at a temperature, understanding these variables allows for control of their growth. This understanding can be used, for example, to preserve certain foods or to treat infections. This lab simulation will use an instrument called a spectrophotometer. This instrument quantitatively measures the amount of light that is absorbed or transmitted by molecules in solution. Microbial populations grow at different rates based on temperature. One way to measure growth is by turbidity measurements. When bacteria multiply in a broth culture they turn the clear solution cloudy, or turbid. a) in your own words explain the proper steps to Inoculate 5°C sterile broth tube using aseptic techniquearrow_forwardDiscuss why the presence of biofilms may be beneficial tomicrobes yet problematic to humans.arrow_forward
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