Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 12, Problem 2MCQ
Summary Introduction
Introduction:
Drugs that are used to treat the microbial infections are commonly referred to as “antimicrobial agents”. Antimicrobial agents that are used in the treatment of helminthic, protozoan, fungal, and viral diseases are grouped as antihelminthic, antiprotozoal, antifungal, and antiviral drugs, respectively
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An antimicrobial drug with a therapeutic index is a betterchoice than one with a therapeutic index.a. low, high
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Chapter 12 Solutions
Microbiology: A Systems Approach
Ch. 12.1 - State the main goal of antimicrobial treatment.Ch. 12.1 - Identify sources of the most commonly used...Ch. 12.1 - Summarize two methods for testing antimicrobial...Ch. 12.1 - Prob. 4AYPCh. 12.2 - Prob. 5AYPCh. 12.2 - Describe the five major targets of antimicrobial...Ch. 12.2 - Identify which categories of drugs are most...Ch. 12.3 - Prob. 8AYPCh. 12.3 - Trace the development of penicillin...Ch. 12.3 - Prob. 10AYP
Ch. 12.3 - Prob. 11AYPCh. 12.3 - Prob. 12AYPCh. 12.3 - Prob. 13AYPCh. 12.3 - Identify the cellular target of quinolones, and...Ch. 12.3 - Prob. 15AYPCh. 12.3 - Prob. 16AYPCh. 12.3 - Prob. 17AYPCh. 12.3 - Prob. 18AYPCh. 12.3 - Describe two major modes of action of antiviral...Ch. 12.4 - Prob. 20AYPCh. 12.4 - Prob. 21AYPCh. 12.4 - Discuss at least three novel antimicrobial...Ch. 12.5 - Distinguish between drug toxicity and allergic...Ch. 12.5 - Prob. 24AYPCh. 12 - Prob. 1MCQCh. 12 - Prob. 2MCQCh. 12 - Prob. 3MCQCh. 12 - Microbial resistance to drugs is acquired through...Ch. 12 - Prob. 5MCQCh. 12 - Prob. 6MCQCh. 12 - Prob. 7MCQCh. 12 - Which of the following modes of action would be...Ch. 12 - Prob. 9MCQCh. 12 - Prob. 10MCQCh. 12 - Prob. 11TFCh. 12 - Prob. 12TFCh. 12 - Biofilms are difficult to treat and do not always...Ch. 12 - Prob. 14TFCh. 12 - Prob. 15TFCh. 12 - Construct a paragraph describing the...Ch. 12 - Prob. 2CTQCh. 12 - Antibiotic-resistance genes, as well as other...Ch. 12 - Prob. 4CTQCh. 12 - What is the significance of the bottom row in...Ch. 12 - Figure 12.5. Where could penicillinase affect each...Ch. 12 - From chapter 6, process figure 6.14a. Describe as...Ch. 12 - Prob. 1CM
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- Which ONE of the following best describes ciprofloxacin? Select one: A. Active against Streptococcus pneumoniae B. An inhibitor of RNA synthesis C. An antimicrobial prodrug D. A natural product produced by Streptomyces spp. E. Subject to new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effectsarrow_forwardWhich clinical situation would be appropriate for treatment with a narrow-spectrum antimicrobial drug? Select one: a.prophylaxis against infection after a surgical procedure b.The treatment of strep throat caused by culture identified as Streptococcus pyogenes c.None of the Above d.the treatment of a polymicrobial mixed infection in the intestine e.Empiric therapy (based on educated guesswork) of pneumonia while waiting for culture resultsarrow_forwardThe list below choose all the concerns surrounding antimicrobial use. A. toxicity B. disruption of normal flora C. allergic reactions D. tolerance of effective dosearrow_forward
- Which of the following medication doses are calculated by using the area under the curve method? A. Carboplatin B. Dacarbazine C. Ifosfamide D. Cyclophosphamidearrow_forwardThere are many bacterial-antimicrobial resistance combinations. Which one of the following is of maior international concern? a. Sulfonamide resistance in Neisseria meningitides b. Penicillin G resistance in N. gonorrhoeae C. Ampicillin resistance in H. influenza d. Erythromycin resistance in S. pyogenes (group A streptococci) e. Vancomycin resistance in S. aureusarrow_forwardWhich of the following statements concerning drug delivery system is INCORRECT?* A.Drugs with good aqueous solubility are good for controlled release formulation. B.The delay-released form is also called extended release form. C.Absorption rate is higher in compressed tablets than that in capsules. D.Drug core with polymer membrane coating belongs to diffusion sustained system. E.Disintegration and dissolution can occur at the same time.arrow_forward
- Choose the combination of answers that most accurately completes the statement. An antimicrobial drug with a ___________ therapeutic index is a better choice than one with a ___________ therapeutic index. a. low, high b. high, lowarrow_forwardWhich ONE of the following best describes nitrofurantoin? Select one: A. A macrolide antimicrobial agent B. An antimicrobial prodrug C. A natural product produced by Streptomyces spp. D. Useful in treating systemic infections E. A nucleic acid synthesis inhibitor Which ONE of the following best describes cephalexin? Select one: A. The bacterial target is located on the internal side of the cytoplasmic membrane B. An agent suitable for community use C. Resistance readily occurs via drug efflux in Gram-positive bacteria D. A parenteral penicillin E. An agent capable of disrupting bacterial membranes Which ONE of the following best describes ciprofloxacin? Select one: A. Active against Streptococcus pneumoniae B. An inhibitor of RNA synthesis C. An antimicrobial prodrug D. A natural product produced by Streptomyces spp. E. Subject to new restrictions and precautions for use due to very rare reports of…arrow_forwardWhich statement is not an aim in the use of drugs for antimicrobialchemotherapy? The drug shoulda. have selective toxicityb. be active even in high dilutionsc. be broken down and excreted rapidlyd. be microbicidalarrow_forward
- Many antibacterial hand soaps contain the chemical agent _____ , which belongs to the _____ antimicrobial category. a. sodium hypochlorite; halogen b. triclosan; phenolic c. sodium chlorite; halogen d. ethanol; alcoholarrow_forwardThe Kirby -Bauer antimicrobial sensitivity testing method relies on: A. The inhibition of one antimicrobial by another B. The diffusion of antimicrobials in paper discs C. Serial dilutions of antimicrobials in test tubes D. A gradient of an antimicrobial on a paper striparrow_forwardMost chemotherapeutic drugs kill cells bya. producing pores in plasma membranes.b. interfering with protein synthesis.c. interfering with cellular respiration.d. interfering with DNA and/or enzymes.e. All of these are correct.arrow_forward
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