Microbiology: A Systems Approach
Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 12, Problem 14TF
Summary Introduction

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Spectrum of action determines the range to which a drug could act upon the pathogen. A drug could be effective against wide range of pathogens or to a narrow range of pathogens. The pathogens sometimes acquire resistance to one or more than one microbial agents. Multiple drug resistance and cross resistance are the types of resistance seen in pathogens against antimicrobial drugs. Microbes have characteristic of drug resistance because they have incredible genetic versatility and adaptability of bacterial population.

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Below are a list of virulence factors/ strategies paired with an example of an organism that utilizes them. How do each of the following strategies contribute to the virulence of the pathogen? Strategy - Causes the host to produce more receptors (Organism - Rhinovirus) Strategy - Produces gas as a product of fermentation (Organism - Clostridium perfringens) Strategy - Produces a capsule (organism - Klebsiella pneumonia) Strategy - Ability to move between adjacent cells (organism - Cytomegalovirus)  Strategy - Ability to use pilus as a motility structure (organism - Pseudomonas aerogenosa)
Explain how specialized structures (e.g., spore, capsule, fimbriae, or flagella) enable a microbe to survive in a given environment or contribute to pathogenesis.
Define the following terms: Bactericidal Bacteriostatic Antisepsis

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Microbiology: A Systems Approach

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