Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 12, Problem 3MCQ
Summary Introduction
Introduction:
Antimicrobial agents differ in its mode of action, including inhibition of cell wall, inhibition of protein and
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Which of the following drugs inhibits protein synthesis through binding to ribosomal 30S subunit:
O a. Linezolid
O b. Amikacin
O c. Ciprofloxacin
O d. Azithromycin
what is the mechanism of action for penicillins?
a. injury to plasma membrane
b. inbibition of protein synthesis
c. inhibition of cell wall synhesis
d. inhibition of nucleic acid synthesis
e. none of the above describes the mechanism of action for penicillins
Which of the following compounds represents a peptidoglycan specific antibiotic ?
A. tetracycline
B. chloramphenicol
C. penicillin
D. aspirin
Chapter 12 Solutions
Microbiology: A Systems Approach
Ch. 12.1 - State the main goal of antimicrobial treatment.Ch. 12.1 - Identify sources of the most commonly used...Ch. 12.1 - Summarize two methods for testing antimicrobial...Ch. 12.1 - Prob. 4AYPCh. 12.2 - Prob. 5AYPCh. 12.2 - Describe the five major targets of antimicrobial...Ch. 12.2 - Identify which categories of drugs are most...Ch. 12.3 - Prob. 8AYPCh. 12.3 - Trace the development of penicillin...Ch. 12.3 - Prob. 10AYP
Ch. 12.3 - Prob. 11AYPCh. 12.3 - Prob. 12AYPCh. 12.3 - Prob. 13AYPCh. 12.3 - Identify the cellular target of quinolones, and...Ch. 12.3 - Prob. 15AYPCh. 12.3 - Prob. 16AYPCh. 12.3 - Prob. 17AYPCh. 12.3 - Prob. 18AYPCh. 12.3 - Describe two major modes of action of antiviral...Ch. 12.4 - Prob. 20AYPCh. 12.4 - Prob. 21AYPCh. 12.4 - Discuss at least three novel antimicrobial...Ch. 12.5 - Distinguish between drug toxicity and allergic...Ch. 12.5 - Prob. 24AYPCh. 12 - Prob. 1MCQCh. 12 - Prob. 2MCQCh. 12 - Prob. 3MCQCh. 12 - Microbial resistance to drugs is acquired through...Ch. 12 - Prob. 5MCQCh. 12 - Prob. 6MCQCh. 12 - Prob. 7MCQCh. 12 - Which of the following modes of action would be...Ch. 12 - Prob. 9MCQCh. 12 - Prob. 10MCQCh. 12 - Prob. 11TFCh. 12 - Prob. 12TFCh. 12 - Biofilms are difficult to treat and do not always...Ch. 12 - Prob. 14TFCh. 12 - Prob. 15TFCh. 12 - Construct a paragraph describing the...Ch. 12 - Prob. 2CTQCh. 12 - Antibiotic-resistance genes, as well as other...Ch. 12 - Prob. 4CTQCh. 12 - What is the significance of the bottom row in...Ch. 12 - Figure 12.5. Where could penicillinase affect each...Ch. 12 - From chapter 6, process figure 6.14a. Describe as...Ch. 12 - Prob. 1CM
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- We have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?arrow_forwardExplain why drugs that effect bacterial ribosomes can be safely used in treating people.arrow_forward1.) Which of the following are criteria for antibiotics? ( Select all that apple) A. Kill viruses B. Chemical substances produced by a microscope C. Effective in small doses D. Stops the growth or kills other microorganisms. 2) which antibiotic inhibits protein synthesis? ( select all that apply) A. Gentamicin B. Amoxicillin C. Erythromycin D. Tetracyclinearrow_forward
- Explain how the antibiotics work... penicillin and aspirin as inhibitors!arrow_forwardIn the discovery of new drugs, the chemical and physical properties of a molecule are very important to be determined. All of the following are physical and chemical properties that are important in drug discovery EXCEPT….A. route of administrationB. fat/water partitionC. molecular steric hindranceD. pHE. pKa Secretion of acid ions from gastric acid, is one of the drug distribution processes by...A. Passive diffusion with facilitiesB. passive diffusionC. dissolves in lipids that make up the membraneD. pinocytosisE. active diffusionarrow_forwardWhat is the specific mode of action and the target organisms of each of the three antibiotics used in the exercise (isolation of E. coli bacteriophage)?a. Ampicillin:b. Polymyxin:c. Streptomycin:arrow_forward
- Identify examples of cell-wall antibiotics that are not beta-lactam drugs.arrow_forwardIntroduction: There’s quite a bit of interest around repurposing extant drugs to treat infections by targeting host pathways that pathogens rely on. Here are a few potential drugs: 1) A drug that inhibits endocytosis, but not phagocytosis. 2) A drug that inhibits degradation of cytoplasmic proteins into smaller peptides, preventing their cycling back into amino acids. 3) A drug used to treat porphyria that reduces the reactivity of heme. 4) A drug that depletes glutathione, a chemical which protects red blood cells against the reactivity of heme. 5) A drug that reduces expression of the ACE-2 protein. Question: Pick a drug and an infection that the drug is likely to be good at treating, or pick an infection and a drug that would most likely make the infection substantially worse. Which drug and pathogen did you pick? Do you think it’ll make it better or worse?arrow_forwardThe first step for directly linking a microbe to a specific disease according to Koch's postulates is to A.isolate microbes from the blood of healthy animals. B. culture the blood or other body fluid from a diseased animal using nutrient medium. C. inject a sample of blood or other body fluid from a diseased animal into a healthy animal. D. obtain a sample of blood or other body fluid from a diseased animal.arrow_forward
- Drugs are often given to patients before going into surgery, to dentalpatients with heart disease, or to healthy family members exposed tocontagious infections.a. What word would you use to describe this use of drugs?b. What is the purpose of this form of treatment?c. Explain some potential undesired effects of this form of therapy.d. Define probiotics and list some ways they are used.arrow_forwardWhich of the following is antiviral drug? O a. Penicillin O b. Streptomycin O c. Acyclovir O d. Allarrow_forwardWhy are the risks associated with antibiotics hard to understand? Please describe in detail with reasoning in a supporting paragraph.arrow_forward
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USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License