Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 11, Problem 9RQ
Summary Introduction
To review:
The compartmentalization of herpes virus genome expression and replication.
Introduction:
The herpesvirus is a group of DNA (deoxyribonucleic acid) virus. It includes herpes simplex virus (HSV), varicella zoster virus, and Epstein-Barr virus among others. Herpes viruses are human pathogens that cause diseases like chicken pox, shingles, Hodgkin’s lymphoma, and cancer.
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After a positive strand RNA virus ( Such as Coronaviruses) enters the host cell, the RNA is translated by ribosomes to create proteins associated with the virus (Such as, for example, the surface antigens like E and Spike proteins). How then, would the genetic material itself be replicated to be incorporated into the new viruses?.
Which statement is true of viral replication?
A) virus attaches to a specific receptor site on the host-cell membrane. B) Once inside the cell, the viral capsid is degraded, and the viral nucleic acid is released. C) Virus uses the host cell’s machinery to replicate and new virus particles are released. D) All of the above
Double-stranded RNA viruses, use the following polymerase for genome synthesis:
A)
viral RNA-dependent RNA polymerase.
B)
host cell DNA-dependent RNA polymerase.
C)
viral DNA-dependent DNA polymerase.
D)
host cell RNA-dependent RNA polymerase.
Chapter 11 Solutions
Microbiology: An Evolving Science (Fourth Edition)
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- The second step in viral replication is entry. For bacteriophage, entry usually involves: O a) direct entry of the nucleic acid into the cell. Ob) phagocytosis. c) membrane fusion mechanism of entry. d) receptor-mediated endocytosis.arrow_forwardWhat is the structure of a virus?arrow_forwardWhat is the significance of the length of a typical viral genome?arrow_forward
- What evolutionary advantage would a retrovirus gain by having the ability to regulate the sites of splicing of its RNA?arrow_forwardWhat is the function of reverse transcriptase in retroviruses? a) It converts viral RNA into double-stranded DNA Ob) It uses viral RNA as a template for making complementary RNA strands Oc) It translates viral RNA into proteins d) It uses viral DNA as a template for RNA synthesisarrow_forwardDescribe Specialized transduction: transfer of specific genetic material by means of a virus carrier.arrow_forward
- 1)What are the difference between RNA and DNA? 2)Describe steps of viral replication, what are the differences in the replication between RNA and DNA viruses ?arrow_forwardThere have been recent outbreaks of dog flu in the US. Why doesn't this virus infect humans? A) The virus can replicate in cells of all species but can only egress from dog cells. B) The genetic code of the virus is the same as that in dog cells but is different from other organisms. C) The virus can only attach to dog cells. D) The virus can enter cells of all species but can only replicate in dog cells.arrow_forwardIf a virus has a negative-sense RNA genome, what enzymatic activity (if any) will be found as part of the virion, and what will be the first step in expression of the viral genome?arrow_forward
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