Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 26PDQ
A genetics student was asked to draw the chemical structure of an adenine- and thymine-containing dinucleotide derived from DNA. His answer is shown below. The student made more than six major errors. One of them is circled, numbered 1, and explained. Find five others. Circle them, number them 2–6, and briefly explain each by following the example given.
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Choose all of the statements that correctly describe the base pairs drawn below.
A
C
H
H-N
-H-N
N-H- -N
B
H
D
موعة Rita
N
-H----
2
NHN
O-
-H-N
H
-H-
N- -H-N
The non-Watson-Crick base pair shown in A is much less stable than the base
pairs shown in B and C, because the smaller size of the two pyrimidine bases
induces a distortion in the structure of the double helix that decreases the
stability of the helix when compared to helices with the normal Watson-Crick
base pairs.
The base pair shown in B is found in BOTH DNA and RNA
The base pair shown in C is found ONLY in RNA and NOT DNA
The base pair seen in B is more stable than the Watson-Crick base pair shown in
C partly because of a larger number of hydrogen bonds and partly because of
more favourable pi-stacking interactions with adjacent base pairs.
DNA sequences have an alphabet {A,C,G,T}.
How many DNA sequences of length n are there? (Two DNA sequences are the same if one is
the reverse of the other).
A compact disc (CD) stores about 4.8 × 109 bits of information in a 96 cm2 area. This information is stored as a binary code—that is, every bit is either a 0 or a 1.
how many bits would it take to specify each nucleotide pair in a DNA sequence?
how many CDs would it take to store the information contained in the human genome?
Chapter 9 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 9 - CASE STUDY |Zigs and zags of the smallpox virus...Ch. 9 -
CASE STUDY | Zigs and zags of the smallpox...Ch. 9 - CASE STUDY | Zigs and zags of the smallpox...Ch. 9 - CASE STUDY | Zigs and zags of the smallpox virus...Ch. 9 -
HOW DO WE KNOW?
1. In this chapter, we have...Ch. 9 - Review the Chapter Concepts list on p. 160. Most...Ch. 9 - Discuss the reasons why proteins were generally...Ch. 9 -
4. Contrast the various contributions made to our...Ch. 9 - When Avery and his colleagues had obtained what...Ch. 9 - Why were 32P and 35S chosen in the Hershey–Chase...
Ch. 9 - Does the design of the Hershey-Chase experiment...Ch. 9 - What observations are consistent with the...Ch. 9 - What are the exceptions to the general rule that...Ch. 9 -
10. Draw the chemical structure of the three...Ch. 9 - How are the carbon and nitrogen atoms of the...Ch. 9 - Adenine may also be named 6–amino purine. How...Ch. 9 -
13. Draw the chemical structure of a dinucleotide...Ch. 9 - Describe the various characteristics of the...Ch. 9 - Prob. 15PDQCh. 9 - What might Watson and Crick have concluded, had...Ch. 9 - Prob. 17PDQCh. 9 - Prob. 18PDQCh. 9 - Prob. 19PDQCh. 9 - Prob. 20PDQCh. 9 - Prob. 21PDQCh. 9 - Prob. 22PDQCh. 9 -
23. Why is Tm related to base composition?
Ch. 9 - What is the chemical basis of molecular...Ch. 9 - What did the Watson–Crick model suggest about the...Ch. 9 - A genetics student was asked to draw the chemical...Ch. 9 - Prob. 27PDQCh. 9 -
28. One of the most common spontaneous lesions...Ch. 9 - Prob. 29PDQCh. 9 - Prob. 30PDQCh. 9 - Prob. 31PDQCh. 9 -
32. During electrophoresis, DNA molecules can...Ch. 9 - Assume that you are interested in separating short...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Match the shorter sequence relative to the longer one. Note: Observe Chargaff's rule of base pairing Longer sequence: T C A C G A T C A G C T C G A A G C A C Shorter sequence: T C G T G Clue: More than one correct answerarrow_forwardDraw the following trinucleotide: pGAUarrow_forwardI have built an urn model for a DNA sequence. I have taken the letters from a sequence 1946 nucleotides long. The urn contains 259 Adenines, 699 Cytosines, 401 Thymines and 587 Guanines How many start codons will I find on average in the entire sequence when I draw all of the bases from the urn without replacement? Please I'm not too sure how to tackle this.arrow_forward
- Design a pair of primers to amplify the entire length of the following 45 base pair sequence.Make each primer 14 bases long. Write the sequences of the primers in 5' to 3' order.(Hint: It will help for you to write out BOTH strands of the DNA sequence listed below.5'-GATGCCCGTTGGATAAATTGGGCGTCTAGAATCGGTCACACTTAG-3'arrow_forwardWhat is the methyl group-containing nucleobase composition of a double- stranded eukaryotic DNA with 52,000 bases that contains 22% bicyclic nucleobases characterized to have both an amino group and a keto group? (Instructions: Do NOT put spaces or commas or additional words/letters/units; Type in your answer in NUMERICAL FORM with the following format: 1234567)arrow_forwardIdentify (and highlight or underline) the one nucleotide difference between the original (left) and altered (right) sequencesarrow_forward
- There are seven common terms usually encountered in the discussion of DNA and the Central Dogma of Molecular Genetics. Find at least 5 of these common terms that these will serve as the introductory terms to understand further this module. Locate and identify them by shading the letters with the color of your choice. Describe or define each term as you identify them.arrow_forwardHN N C N H₂N HN پرسپولیو D B CH₂ -N N NH₂ E When part of a nucleotide in a nucleic acid chain, which of the following may base pair with thymine nucleotides? Choose all correct answers and assume normal Watson-Crick base pairing.arrow_forwardUsing the first and second base key below, predict the DNA sequence given by the SOLID color sequence. For the key G = green, R = red, Y = yellow, and B = blue. Note that the first base of the sequence is already given ("A"). Give the remaining 8 bases for this sequence. A First base A CCT Second base A CGT BGY R GBRY RBG R Y (G) B Y G)(R) GB )( R )( Y ) ( G) Barrow_forward
- Name the following nucleotide.arrow_forwardWe have talked about several examples of cis-acting elements that have dyad symmetry (inverted repeat symmetry). Some function on the level of DNA, and others function on the level of RNA. Give one example of one that functions at the DNA level and briefly explain why the sequence requires dyad symmetry to work properly. Note: you don't have to give an exact sequence, just the name of the element. Edit View Incort Format Tools Tabloarrow_forwardWhat is the sequence of the unknown DNA sample? (You should give the 5' and 3' ends). Use the gel sequence given below and write also the ingredients used in manual DNA sequencing. Use an empty paper and upload your drawing. || A - T C 0 ||||arrow_forward
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