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Raising a King
The mitochondrial DNA (mtDNA) that identified Richard III serves a unique role in the human body. Although the human nucleus has about 20,000 genes. mtDNA has only 37. Twenty-four of these code for RNA that helps translate genes into proteins, and the remaining 13 genes code for proteins that are subunits of enzymes that participate in the ETC and chemiosmosis. Some contribute to the ETC enzymes that cause NADH and FADH2 to release their high-energy electrons into the chain. Other mtDNA genes help to produce the final enzyme in the chain, which combines the energy-depleted electrons with oxygen, forming water. Some genes in mtDNA code for parts of the ATP synthase enzyme on the inner mitochondrial membrane. If mtDNA were to disappear,
We’ve seen how NADH and FADH2 can gain high-energy electrons that originated in glucose. Can these electron carriers also obtain high-energy electrons from other molecules in our diets, such as fat or protein?
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Biology
- A scientist notices that a cancer cell line shows high levels of phosphorylated ERK in the absence of EGF. What are two possible explanations for the increase in phosphorylated ERK? Be specific in which proteins are involved.arrow_forwardMake a rough drawing of the ATP synthase machinery within the mitochondrial membrane and specifically label the Fo and F1 subunits, as well as the C-ring, the a subunit, the y stalk and the a3ß3 hexamer.arrow_forwardIn the 1930’s DNP was given to people to lose weight. DNP makes the mitochondrial membrane leaky to hydrogen ions. Why might this cause one to lose weight? Why would this cause death? How is this similar or different to cyanide which binds to complex IV in the mitochondria?arrow_forward
- Most diseases are caused by disruptions in cellular function. You are to research a disease that is a disturbance at the cellular level. Usually, there are problems with the organelles within the cells. So essentially, you can look up things like....mitochondrial diseaselysosomal disorderscellular receptor disorders Once you have found a disease you should include the following in your 2 paragraph summary.1-Description and how is occurs2-Is it genetic?3-Are there cures?4-What does research show as far as cures or treatments?5-How does it affect one's life?arrow_forwardIn the Q Cycle of Complex III, the two electrons from QH2 are split up and go to different places. Why must the electrons be split up?arrow_forwardThe Q cycle plays a major role in the electron-transport chain of mitochondria, chloroplasts, and bacteria. What is the function of the Q cycle, and how does it carry out this function?arrow_forward
- Aerobic respiration, used by the mitochondria of eukaryotic cells, is best represented by which of the following balanced equations? 6CO2 + 12H2S g C6H12O6 + 6S2 + 6H2O C6H12O6 + 6O2 + 6H2O g 6CO2 + 12H2O C12H22O11 + H2O g C6H12O6 + C6H12O6 6CO2 + 12H2O g C6H12O6 + 6O2 + 6H2O C6H12O6 + C6H12O6 g C12H22O11 + H2Oarrow_forward--As glucose is split in the cytosol of the cell, is there a release of carbon dioxide as by-product of the reaction?arrow_forwardThe enzymes GICNAC phosphotrasnferase is a key enzyme involved in the transporting of proteins from the trans-Golgi to the lysozyme. In addition to the catalytic function of the enzyme that involves certain sugars, what is the second critical function of this enzyme? O It recognizes internal signal sequences found on lysozyme-targeted proteins. O It drives the binding of a phosphorylated GlcNac group onto a mannose residue. O It facilitates the reversible binding of specific proteins to the M6P receptor O In is essential for the recruitment of clathrin triskelions to the budding vesicle.arrow_forward
- In the presence of oxygen, the mitochondrion in yeast is used for aerobic respiration,however, under anaerobic conditions,the yeast mitochondria have been found to have other function. Identify and briefly discuss four of these functionsarrow_forwardWhich of the following is TRUE about cytochrome c protein? As a part of the ETC chain, it changes conformation to allow H+ ions to flow out of the matrix. It is found on the surface of the inner mitochondrial membrane and, therefore, contains start-transfer and/or stop-transfer sequences. With assistance from Bax, it can move out of the mitochondria and into the cytosol. It is considered a symporter because it is involved in electron transport. It is able to puncture holes in the plasma membrane to initiate apoptosis.arrow_forwardDNA damage can suppress the activity of the following cyclin-dependent kinases EXCEPT G1/S-Cdk S-Cdk M-Cdk G1-Cdk Which phenomenon allows the formation of double and triple bonds between carbon atoms? * Reduction Radioactivity Oxidation Hybridization If an agent that disrupts microtubules activity was added to cells at M phase, the cells will ble expected to get arrested at Anaphase O Metaphase O Prophase Telophase O 0 Oarrow_forward
- Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax