The enzymes GlcNAc phosphotrasnferase is a key enzyme involved in the transporting of proteins from the trans-Golgi to the lysozyme. In addition to the catalytic function of the enzyme that involves certain sugars, what is the second critical function of this enzyme? O It recognizes internal signal sequences found on lysozyme-targeted proteins. O It drives the binding of a phosphorylated GlcNac group onto a mannose residue. O It facilitates the reversible binding of specific proteins to the M6P receptor O In is essential for the recruitment of clathrin triskelions to the budding vesicle.

PFK-1 is actually a tetramer with four identical active sites that produced fructose 1,6-bisphosphate.  There are also allosteric sites for citrate and ATP/ADP on each subunit as well which influence how well the active sites are binding substrates or producing product.  The arginine at position 48 on each PFK-1 subunit normally forms a salt bridge with a negatively charged oxygen on phosphate in the catalytic interface of PFK-1.  Speculate on how the R48C mutation might change this function.

What effect does binding of the IRF protein to the IRE in the mRNA encoding ferritin have on the production of ferritin? Briefly explain why this effect is observed.

Which of the following sequences represents a recognition site for N-linked glycosylation where X is any amino acid residue? Gln-X-Ser O His-X-Ser O Arg-X-Ser O Asn-X-Ser O Asp-X-Ser

Insulin resistance, as occurs in type 2 diabetes, may lead to increased ketone production and release into blood. Describe the biochemistry that links insulin resistance and ketone production. Compare the cellular energy (e.g. ATP) required and produced when glycogen is synthesize and hydrolyzed, respectively. Compare and contrast the mechanism of fatty acid synthase with translation. When young rats are placed on a totally fat acid free diet, they grow poorly, develop a scaly dermatitis, lose hair, and soon die these symptoms that can be prevented if plant material is included in the diet. Why?

The activity of the enzyme β-galactosidase produced bywild-type cells grown in media supplemented with different carbon sources is measured. In relative units, thefollowing levels of activity are found:Glucose Lactose Lactose + glucose0 100 1Predict the relative levels of β-galactosidase activity incells grown under similar conditions when the cells arelacI−, lacIS, lacO+, and crp−.

From the complete oxidation of glucose (glucose  →  6CO2), how many total nucleotide triphosphates are yielded (be sure to deduct payback) as part of substrate level phosphorylation?

In the normal cycle of Ras activity, when Ras is bound to y activity that removes a phosphate to convert GTP back to GDP and this it is inactive. Activation of Ras involves exchanging GDP for The Ras protein has intrinsic Ras. inactivates activates ATP GTP «< Questic A Moving to another question will save this response. ADP GDP GTPase Clo nuclease

for question 1, choose wheater each statement is true or false for quesiton 2, choose the wheater each statement is true or false

Once the chains of peptides that make up lysyl-tRNA synthetase protein are synthesized in ribosomes, lysyl-tRNA synthetase needs to have the proper active site in order to perform its function, explain the process of protein folding necessary to have a proper 3-D structure, include effect of thermodynamics and different states in folding, including what happen when there are prolines that form peptide bonds with other amino acids, and any disulfide bridges