The sex-limited and sex-influenced traits on the basis of the fact that hormones interact with DNA to turn certain genes on and off. Introduction: There are obvious phenotypic differences among males and females. The differences between the sexes in humans are emphasized with the help of secondary sex characteristics which include the body size, the patterns of fat distribution, muscle mass, and the development of male or female sex organs such as penis or vagina respectively.

Question

The drug tamoxifen has been used to treat some types of breast cancer. Suppose even among female patients with the same tumor grade there is variation in responsiveness to tamoxifen. It is also found that this variation is at least partly genetic; his variation is at least partly genetic; women with a relative who had a low responsiveness to the drug are at higher risk of low responsiveness to the drug The target of tamoxifen is a protein called the estrogen receptor. A. Outline how a “candidate gene approach” could be conducted to investigate whether variation in the gene for estrogen receptor affects tamoxifen responsiveness

Answer 1

Question

Chapter 7, Problem 13QP

Summary Introduction

To explain: The sex-limited and sex-influenced traits on the basis of the fact that hormones interact with DNA to turn certain genes on and off.

Introduction: There are obvious phenotypic differences among males and females. The differences between the sexes in humans are emphasized with the help of secondary sex characteristics which include the body size, the patterns of fat distribution, muscle mass, and the development of male or female sex organs such as penis or vagina respectively.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Students have asked these similar questions

The drug tamoxifen has been used to treat some types of breast cancer. Suppose even among female patients with the same tumor grade there is variation in responsiveness to tamoxifen. It is also found that this variation is at least partly genetic; his variation is at least partly genetic; women with a relative who had a low responsiveness to the drug are at higher risk of low responsiveness to the drug The target of tamoxifen is a protein called the estrogen receptor. A. Outline how a “candidate gene approach” could be conducted to investigate whether variation in the gene for estrogen receptor affects tamoxifen responsiveness

Behavioral geneticists attempted the controversial goal of rooting complex social and behavioral traits like intelligence, educational attainment, or even sexual preference to genetic differences between individuals. In pursuit of these goals, linkage studies and GWAS eventually identified hundreds of genetic variants associated with such behavioral traits. Describe the methods used in large-scale studies on same-sex sexual behavior. Summarize results of such studies. What is your reaction to such findings? Are you convinced that there are indeed gay genes?

Hi, I'm having some trouble with this practice problem from my study guide. If anyone can explain it it would be very helpful! Brindle coloration is a black and brown striping pattern in some dogs. This fur coloration is controlled by different alleles at a single autosomal locus. There are three alleles, KB, kbr and ky. The KB allele is dominant over the other two alleles and produces a solid black color. The allele kbr produces the brindle color pattern and is dominant over the ky allele, which produces yellow fur. Give the genotypes of the parents and offspring in each cross. P: black X yellow; F1: ½ brindle and ½ black P: black X brindle; F1: ½ black, ¼ brindle and ¼ yellow P: brindle X yellow; F1: 100% brindle