Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 6, Problem 4CS
Summary Introduction

To determine: The ethical responsibilities of a pediatrician for the present and future patients to provide effective treatment in the form of antibiotics.

Introduction: The ability of microorganisms or bacteria to resist the effect of the antibiotics to which they were once sensitive, is known as antibiotic resistance. Antibiotic resistance occurs when the bacteria changes and become resistant to chemical or drugs or antibiotics.

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You are designing a phage therapy for a cystic fibrosis patient with an multi-antibiotic resistant Mycobacterium infection. The Mycobacterium infection is preventing the patient from taking immunosuppressant drugs that are needed for a successful lung transplant. The idea is that introducing the right phage to the patient will kill the Mycobacterium cells and allow the patient to go on immunosuppressant drugs that will ensure the new lung is not rejected by the body.  You need to find a phage that infects the Mycobacterium you isolated from the patient. Which TWO options have the highest chance of success? A. Screening a colleague's library of known Mycobacterium phages for phage that infect the patient's Mycobacterium isolate   b. Choosing likely candidates from analysis of phage 16S rRNA phylogeny in the tree of life   C. Isolating new phage from soil using a plaque assay with the Mycobacterium isolate   D. Obtaining a very well-studied phage, such as T4 bacteriophage, that…
You are designing a phage therapy for a cystic fibrosis patient with an multi-antibiotic resistant Mycobacterium infection. The Mycobacterium infection is preventing the patient from taking immunosuppressant drugs that are needed for a successful lung transplant. The idea is that introducing the right phage to the patient will kill the Mycobacterium cells and allow the patient to go on immunosuppressant drugs that will ensure the new lung is not rejected by the body.  You finally find a phage that you think will work because it attaches to and injects its genome into the patient's Mycobacterium isolate. Next, you need to be sure of what characteristics of the phage infection cycle? Pick all that are true  A. That the phage delivers new antibiotic resistance genes to Mycobacterium via transduction B. That the correct proteins are expressed during the phages metabolism C. That the infection is lytic D.That lysogeny is the primary infection pathway
You are designing a phage therapy for a cystic fibrosis patient with an multi-antibiotic resistant Mycobacterium infection. The Mycobacterium infection is preventing the patient from taking immunosuppressant drugs that are needed for a successful lung transplant. The idea is that introducing the right phage to the patient will kill the Mycobacterium cells and allow the patient to go on immunosuppressant drugs that will ensure the new lung is not rejected by the body.  You need to find a phage that infects the Mycobacterium you isolated from the patient. Which TWO options have the highest chance of success?   Group of answer choices 1.Isolating new phage from soil using a plaque assay with the Mycobacterium isolate 2.Choosing likely candidates from analysis of phage 16S rRNA phylogeny in the tree of life 3.Obtaining a very well-studied phage, such as T4 bacteriophage, that specifically targets E. coli 4.Screening a colleague's library of known Mycobacterium phages for phage that…

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Concepts of Genetics (12th Edition)

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