Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 5.4, Problem 23CC
Liver cells (hepatocytes) are able to convert glycogen to glucose, thereby making the intracellular glucose concentration higher than the extracellular glucose concentration. In what direction do the hepatic GLUT2 transporters carry glucose when this occurs?
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Transport of glucose across the basolateral membrane of intestinal epithelial cells and into the vascular system requires which of the following conditions to occur?
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Chapter 5 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 5.1 - If the 58-kg Reference Woman has total body water...Ch. 5.1 - A mother brings her baby to the emergency room...Ch. 5.1 - Prob. 6CCCh. 5.1 - Two compartments are separated by a membrane that...Ch. 5.1 - Prob. 8CCCh. 5.1 - Prob. 9CCCh. 5.1 - Prob. 10CCCh. 5.3 - If the distance over which a molecule must diffuse...Ch. 5.3 - Prob. 12CCCh. 5.3 - Which is more likely to cross a cell membrane by...
Ch. 5.3 - Prob. 14CCCh. 5.3 - Prob. 15CCCh. 5.3 - Prob. 16CCCh. 5.4 - Positively charged ions are called _____, and...Ch. 5.4 - Name four functions of membrane proteins.Ch. 5.4 - Prob. 19CCCh. 5.4 - Prob. 20CCCh. 5.4 - If a channel is lined with amino acids that have a...Ch. 5.4 - Prob. 22CCCh. 5.4 - Liver cells (hepatocytes) are able to convert...Ch. 5.4 - Prob. 24CCCh. 5.5 - What would you call a carrier that moves two...Ch. 5.5 - Prob. 26CCCh. 5.5 - Prob. 27CCCh. 5.5 - Name the two membrane protein families associated...Ch. 5.5 - Prob. 29CCCh. 5.6 - Prob. 30CCCh. 5.6 - Prob. 31CCCh. 5.6 - Prob. 32CCCh. 5.6 - Prob. 33CCCh. 5.7 - Prob. 34CCCh. 5 - Using what you learned about the naming...Ch. 5 - Prob. 2CCCh. 5 - Prob. 3CCCh. 5 - Prob. 1RQCh. 5 - Distinguish between active transport and passive...Ch. 5 - Which of the following processes are examples of...Ch. 5 - List four factors that increase the rate of...Ch. 5 - List the three physical methods by which materials...Ch. 5 - A cotransporter is a protein that moves more than...Ch. 5 - Prob. 7RQCh. 5 - Prob. 8RQCh. 5 - Prob. 9RQCh. 5 - What determines the osmolarity of a solution? In...Ch. 5 - Prob. 11RQCh. 5 - Prob. 12RQCh. 5 - Prob. 13RQCh. 5 - Prob. 14RQCh. 5 - The membrane potential at which the electrical...Ch. 5 - Prob. 16RQCh. 5 - Create a map of transport across cell membranes...Ch. 5 - Draw a large rectangle to represent the total body...Ch. 5 - What factors influence the rate of diffusion...Ch. 5 - Define the following terms and explain how they...Ch. 5 - Prob. 21RQCh. 5 - Prob. 22RQCh. 5 - Prob. 23RQCh. 5 - Prob. 24RQCh. 5 - Prob. 25RQCh. 5 - Prob. 26RQCh. 5 - The following terms have been applied to membrane...Ch. 5 - Prob. 28RQCh. 5 - NaCl is a nonpenetrating solute and urea is a...Ch. 5 - Prob. 30RQCh. 5 - Prob. 31RQCh. 5 - What is the osmolarity of half-normal saline (=...Ch. 5 - Prob. 33RQCh. 5 - Prob. 34RQ
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- Individuals with McArdle’s disease often experience a “second wind” resulting from cardiovascular adjustments that allow glucose mobilized from liver glycogen to fuel muscle contraction. Explain why the amount of ATP derived in the muscle from circulating glucose is less than the amount of ATP that would be obtained by mobilizing the same amount of glucose from muscle glycogen.arrow_forwardWhy is glucose provided by glycogenolysis in the liver but not in skeletal muscle?arrow_forwardIf a mutation in a sodium channel in an Intestinal epithelial cell caused a marked decrease In the concentration gradient of sodium across the plasma membrane, which of the following would you expect to observe? a decrease in Na/K ATPase activity. an increase in the movement of glucose across the basolateral membrane to the extracellular space an increase in sodium/glucose co-transport into the cell across the apical membrane a decrease in cytoplasmic glucose concentrationarrow_forward
- Glucose-6-phosphatase is located inside the endoplasmic reticulum. Describe the probable symptoms of a defect in G6P transport across the endoplasmic reticulum membrane.arrow_forwardAcetylcholine is a neurotransmitter that, when bound to its receptor, causes the receptor to open a channel that allows the flow of Na+ ions into neurons. When the Na+ ions begin to flow into the neuron, this change in the net charge across the neuronal cell membrane often triggers Ca2+ ion channels to open. In this scenario, the acetylcholine receptor would be acting as a channel, and the Ca2+ channels would be classified as voltage-gated; leaky ligand gated; voltage-gated symporter; antiporter None of the above. ionarrow_forwardDiabetes mellitus is a set of metabolic diseases with the common symptom of an inability to transport glucose into target cells (muscle cells and adipocytes). The body compensates in part by degrading muscle protein to generate energy. Explain how this process works.arrow_forward
- Which of the following statements best describes the absorption of glucose? Absorption of glucose requires digestion by aminopeptidases on absorptive epithelial microvilli before absorption of the carbohydrate smaller units such as glucose. Absorption of glucose requires an electrochemical gradient of high extracellular K+ set up by primary active transport. Absorption of glucose occurs at villi and crypts mainly in the duodenum where amylases break down carbohydrates into glucose. Absorption of glucose occurs at the transporting epithelia in the small intestine and is a secondary active transport that requires a Na+gradientarrow_forwardHow does the Na+/ K+ ATPase play a role in glucose transport? phosphorylates GLUT1 to activate it pumps Na+ across plasma membranes into cytoplasm to activate the sodium-glucose transporter pumps Na+ across basal plasma membrane to the outside of intestinal cells so that co-transport of glucose with Na+ into cytoplasm is facilitated allows for the diffusion of K+ inside of cell so that co-transport with glucose is facilitatedarrow_forwardit is known that exercise is good for diabetics. explain how GLUT 4 transporters may be involved in this beneficial effect of exercise.arrow_forward
- Insulin signals activate all of the following enzymes except: Phosphoinositide 3-kinase (PI3K) Glycogen synthase kinase 3 (GSK3) Protein kinase B (PKB; or Akt) All of the above enzymes are activated by insulin signals Citrate move in and out of mitochondria via a specific transport protein. What would happen if aninhibitor completely inhibited this transport system? Fatty acid biosynthesis would slow down Ketone body synthesis would slow down Both A and B Neither A nor Barrow_forwardIn type II diabetes, insulin is produced but is nonfunctional. These individuals are described as “starving in the sea of plenty” because their blood glucose levels are high, but none of the glucose is transported into the cells. Describe how this leads to malnutrition.arrow_forwardMany diabetics do not respond to insulin because of a deficiency of insulin receptors on their cells. How does this aff ect (a) the levels of circulating glucose immediately after a meal and (b) the rate of glycogen synthesis in muscle?arrow_forward
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