Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 5, Problem 26RQ
Summary Introduction
To determine: The mechanism by which insulin lowers blood glucose levels.
Introduction: Insulin is a type of peptide hormone, which is produced by the beta cells of the pancreatic islets. Insulin regulates the
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Chapter 5 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 5.1 - If the 58-kg Reference Woman has total body water...Ch. 5.1 - A mother brings her baby to the emergency room...Ch. 5.1 - Prob. 6CCCh. 5.1 - Two compartments are separated by a membrane that...Ch. 5.1 - Prob. 8CCCh. 5.1 - Prob. 9CCCh. 5.1 - Prob. 10CCCh. 5.3 - If the distance over which a molecule must diffuse...Ch. 5.3 - Prob. 12CCCh. 5.3 - Which is more likely to cross a cell membrane by...
Ch. 5.3 - Prob. 14CCCh. 5.3 - Prob. 15CCCh. 5.3 - Prob. 16CCCh. 5.4 - Positively charged ions are called _____, and...Ch. 5.4 - Name four functions of membrane proteins.Ch. 5.4 - Prob. 19CCCh. 5.4 - Prob. 20CCCh. 5.4 - If a channel is lined with amino acids that have a...Ch. 5.4 - Prob. 22CCCh. 5.4 - Liver cells (hepatocytes) are able to convert...Ch. 5.4 - Prob. 24CCCh. 5.5 - What would you call a carrier that moves two...Ch. 5.5 - Prob. 26CCCh. 5.5 - Prob. 27CCCh. 5.5 - Name the two membrane protein families associated...Ch. 5.5 - Prob. 29CCCh. 5.6 - Prob. 30CCCh. 5.6 - Prob. 31CCCh. 5.6 - Prob. 32CCCh. 5.6 - Prob. 33CCCh. 5.7 - Prob. 34CCCh. 5 - Using what you learned about the naming...Ch. 5 - Prob. 2CCCh. 5 - Prob. 3CCCh. 5 - Prob. 1RQCh. 5 - Distinguish between active transport and passive...Ch. 5 - Which of the following processes are examples of...Ch. 5 - List four factors that increase the rate of...Ch. 5 - List the three physical methods by which materials...Ch. 5 - A cotransporter is a protein that moves more than...Ch. 5 - Prob. 7RQCh. 5 - Prob. 8RQCh. 5 - Prob. 9RQCh. 5 - What determines the osmolarity of a solution? In...Ch. 5 - Prob. 11RQCh. 5 - Prob. 12RQCh. 5 - Prob. 13RQCh. 5 - Prob. 14RQCh. 5 - The membrane potential at which the electrical...Ch. 5 - Prob. 16RQCh. 5 - Create a map of transport across cell membranes...Ch. 5 - Draw a large rectangle to represent the total body...Ch. 5 - What factors influence the rate of diffusion...Ch. 5 - Define the following terms and explain how they...Ch. 5 - Prob. 21RQCh. 5 - Prob. 22RQCh. 5 - Prob. 23RQCh. 5 - Prob. 24RQCh. 5 - Prob. 25RQCh. 5 - Prob. 26RQCh. 5 - The following terms have been applied to membrane...Ch. 5 - Prob. 28RQCh. 5 - NaCl is a nonpenetrating solute and urea is a...Ch. 5 - Prob. 30RQCh. 5 - Prob. 31RQCh. 5 - What is the osmolarity of half-normal saline (=...Ch. 5 - Prob. 33RQCh. 5 - Prob. 34RQ
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- Here's one experimental approach to finding out how rapidly a membrane transporter can move its solute into the cell: combine biochemical information about how much solute accumulates in the cell over time with structural information about how many transporters are on the surface of the cell. You are studying a spherical eukaryotic cell that has a diameter of 20 um and is engaged in glycolysis. Its energy source is glucose, which it is taking up from its environment via Na/glucose symporters distributed throughout the surface of its plasma membrane. By briefly adding an inhibitor of all glucose breakdown, you are able to determine that glucose accumulates in the cell at the rate of (5.000x10^1) µM/hr. Based on this number, how many umoles of glucose must be entering the cell per hour? (Assume that one-half of the volume of the cell is composed of organelles, and thus not available for diffusion of glucose). Put your final answer in umol/hr.arrow_forwardImagine a hypothetical cell with a higher concentration of glucose inside the cell thanoutside. Answer the following questions about this cell, assuming all transport acrossthe membrane is passive, not active.a. Can the glucose simply diffuse across the cell membrane? Why or why not?b. If there are glucose transport proteins in the cell membrane, which way wouldglucose flow- into or out of the cell? Explain your answer.c. If the concentration of glucose was equal inside and outside of the cell, do you thinkthere would be a net flow of glucose across the cell membrane in one direction orthe other? Explain your answer.arrow_forwardThe parasite Trypanosoma brucei, which causes sleeping sickness, uses proline as an energy source during one stage of its life cycle. The properties of this proline-specific transporter were investigated in a series of experiments. L-hydroxyproline inhibited the transporter. D-proline did not inhibit the transporter. Na*, K*, and pH changes did not affect the transporter. Which of the following is a reasonable hypothesis based on this data? The proline transporter is a Na+-K+ ion pump. The proline transporter cleaves amide bonds. The proline transporter is stereospecific. The proline transporter requires metal-ion catalysis. The proline transporter has an essential ionizable histidine residue,arrow_forward
- Cells transporting substances across their membranes is essential. Choose TWO of the following types of cellular transport. ๏osmosis ๏active transport ๏facilitated diffusion ๏endocytosis / exocytosis (a)For each type of transport you choose, describe the transport process. Explain how the organization of cell membrane plays a role the movement of specific molecules across membrane. (b)Using the same transport types, identify a specific cell that utilizes that type of transit (i.e. one cell for each transport type, or two different cell examples), and detail a substance that is transferred. (c)A typical human lymphocyte has a radius of about 10 μm, while a typical bacterium (e.g., S. pneumoniae) has a radius of about 1 μm. Assuming that both cell types are perfectly spherical, compare and contrastthe transport mechanisms for each of these cells.arrow_forwardWhat is another way to answer this question Describe various examples of active transport. How is active transport different from passive transport? Without saying this: Active transport is when cells move against the flow/ concentration gradient, moving from low concentrations to high concentrations. Because of this, active transport requires ATP to work. Passive transport is different because it doesn't use much energy and moves from high concentration to a low concentration. Some examples of active transport are the Sodium-potassium pump ( the most well known one) where it takes sodium ions and pumps them outside of the membrane to let in potassium ions. Another one in plants is when a plant receives ions from the soil. The soil has a much lower concentration of ions than a plants root does, so ions have to move against the concentration gradient. Endocytosis and exocytosis are also forms of active transport. Where cells engulf its self around large molecules to bring…arrow_forwardBiological membranes are selectively permeable, allowing certain molecules to cross the membrane, but not others. Classify the molecules or ions depending on how they cross a biological membrane. Note that some of these examples may also utilize active transport to traverse a membrane. However, this question is limited to passive transport processes only. Ca²+ Simple Diffusion CO₂ fatty acids glucose Answer Bank steroid hormones Facilitated Diffusionarrow_forward
- The electrochemical gradient across the plasma membrane is important for cellular functions including protein transport and information transfer. Pinpoint the specific protein and explain how it maintains the electrochemical gradient.arrow_forwardOuabain is a specific inhibitor of the active transport of sodium ions out of the cell and is therefore a valuable tool in studies of membrane transport mechanisms. Which of the following processes in your own body would you expect to be sensitive to inhibition by ouabain? Explain your answer in each case. a) Facilitated diffusion of glucose into a muscle cell b) Active transport of dietary phenylalanine across the intestinal mucosa c) Uptake of potassium ions by red blood cells d) Active uptake of lactose by the bacteria in your intestinearrow_forwardName the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3−) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms. What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forward
- An important aspect of cell metabolism is the movement of molecules across the cell membrane. Molecules generally move down an electrochemical gradient however in many instances the opposite is required. Explain how transporters can move molecules against their electrochemical gradient – discuss the mechanism of action of sarcoplasmic reticulum Ca2+ pumps and sodium-glucose co-transporters in your answer.arrow_forwardthe movement of glucose across the cell membrane through facilitated diffusion is a form of passive transport becausearrow_forwardGlucose can be transported into cells with a glucose/sodium symporter. If the extracellular concentration of sodium is always in excess to that of glucose, which of these manipulations would MOST increase the rate of glucose transport into a cell? A. increase in the extracellular concentration of sodium B. increase in the intracellular concentration of sodium C. increase in the extracellular concentration of glucose D. increase in the intracellular concentration of glucosearrow_forward
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The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license