If a mutation in a sodium channel in an Intestinal epithelial cell caused a marked decrease In the concentration gradient of sodium across the plasma membrane, which of the following would you expect to observe? a decrease in Na/K ATPase activity. an increase in the movement of glucose across the basolateral membrane to the extracellular space an increase in sodium/glucose co-transport into the cell across the apical membrane a decrease in cytoplasmic glucose concentration

If a mutation in a sodium channel in an Intestinal epithelial cell caused a marked decrease In the concentration gradient of sodium across the plasma membrane, which of the following would you expect to observe? a decrease in Na/K ATPase activity. an increase in the movement of glucose across the basolateral membrane to the extracellular space an increase in sodium/glucose co-transport into the cell across the apical membrane a decrease in cytoplasmic glucose concentration

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter3: The Plasma Membrane And Membrane Potential

Section: Chapter Questions

Problem 1ACR: When William H. was helping victims after a devastating earthquake in a region not prepared to...

See similar textbooks

Related questions

Q: Movement of glucose from one side to the other side of the intestinal epithelium is a major example…

A: The concentration gradient is one that helps the polar molecules as well as the ions to easily get…

Q: Is caused (indirectly) by the binding of a glucagon molecule to its receptor on the surface of a…

A: The glycogen metabolism is controlled by the activity of glycogen synthase and glycogen…

Q: Events that occur in the peroxisomes incluce the following EXCEPT oxidation of fatty acids…

A: Peroxisomes are small, membrane-bound organelles in eukaryotic cells that contain enzymes involved…

Q: An anti-enzyme drug Gordox is extracted from the pancreas of cattle and is used in the treatment of…

A: Enzymes are proteinaceous substances which acts as biocatalysts in living organisms which increases…

Q: The micrographs of areolar and adipose tissue both show cells (fibroblasts and adipocytes), but the…

A: Tissues are a group of cells having similar functions and structure. The different types of tissues…

Q: NH4+ is transported indirectly in the body. Why can’t free NH4+ be transported in the blood? How is…

A: NH4+ is the waste product formed from the amino acids on their catabolism. It must be transported…

Q: Which of the following correctly describes ATP usage in gluconeogenesis and glycolysis? O ATP is…

A: The metabolic pathway can be defined as the combination of chemical reactions occurring in a…

Q: The intravenous infusion of fructose into healthy volunteers leads to a two- to fivefold increase in…

A: Fructose : It is a simple ketonic simple sugar found in many plants, where it is often bonded to…

Q: Glucose transporters are either open to the extracellular side or open to the intracellular side of…

A: Membrane transporters are primarily of 3 types.ChannelsPrimary active transportersSecondary active…

Q: Rate of glucose transport The below graph plots the rate of glucose transport through a membrane…

A: GLUT transporters are found in various tissues and these transporters are responsible for the…

Q: The reason ions such as Na+, K+, and Ca2+ diffuse across plasma membranes more rapidly than would be…

A: Plasma membrane is a cell membrane that is found in all cells, this seperates the interior from…

Q: Nitric oxide (NO) is a gaseous molecule with lipid solubility similar to that of O2 and CO2.…

A: ANSWER: Nitric oxide (NO) is a gaseous molecule involved in several physiological and pathological…

Q: The Na+ /glucose symport transports glucose from the lumen of the smallintestine into cells lining…

A: Symport is a type of cellular transport that involves coupled movement of two solutes in same…

Q: Which one of the following is found on cells that line the capillary wall of blood vessels adjacent…

A: Lipoprotein lipase (LPL) to be a vascular endothelial extracellular enzyme that degrades circulating…

Q: A. Energy is released in the process of lipid degradation. (i) Into which form is the fatty acid…

A: Introduction Fatty acids are degraded by the sequential removal of two-carbon fragments from the…

Q: Glucose is transported across the cell membrane of intestinal cells. The cells lining the small…

A: Transportation and absorption of glucose take place in the small intestine and the proximal…

Q: Enzymes that digest dietary proteins in the stomach and intestine are synthesized as proenzymes or…

A: The options are not correct. Still we are answering the question based on the general concept. An…

Q: For each of the following molecules determine how much ATP would be net from aerobic cellular…

A: The cellular respiration that takes place in presence of oxygen is called aerobic cellular…

Question

a decrease in Na/K ATPase activity.
an increase in the movement of glucose across the basolateral membrane to the extracellular space
an increase in sodium/glucose co-transport into the cell across the apical membrane
a decrease in cytoplasmic glucose concentration

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step 3

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

Movement of glucose from one side to the other side of the intestinal epithelium is a major example of transcellular transport. How does the Na+/K+ ATPase power the process? Why are tight junctions essential for the process? Why is localization of the transporters specifically in the apicalor basolateral membrane crucial for transcellular transport? Rehydration supplements such as sport drinks include a sugar and a salt. Why are both important to rehydration?
The diagram below depicts an intestinal epithelial cell, as well as the relative concentrations of a number of different solutes. Sodium (Na+) ions within epithelial cells have a low concentration relative to that in the lumen and lamina propria, while chloride (Cl-) and potassium ions (K+), as well as glucose, have a relatively high concentration within the cell. Which of the following requires active transport? (select two answers) transport of K+ and Cl- from the cytosol to the lamina propria transport of glucose from the intestinal lumen to the cytosol transport of Cl- from the cytosol to the intestinal lumen transport of Na+ from the lamina propria to the cytosol transport of K+ from the lamina propria to the cytosol
Fill in the blanks: One example of transepithelial transport is the system in intestinal epithelial cells that includes the in the intestine-facing membrane, the energy facing the blood, allowing facilitated diffusion out of the cell into the blood. requiring and the Na+/glucose cotransporter, Glut2, CFTR O Na+/glucose cotransporter, Na+/K+ ATPase, Glut2 Na+/K+ ATPase, Na+/glucose cotransporter, Glut2 Glut2, Na+/glucose cotransporter, Na+/K+ ATPase O Na+/glucose cotransporter, CFTR, Glut2
Transport of glucose across the basolateral membrane of intestinal epithelial cells and into the vascular system requires which of the following conditions to occur? Select one: a. Sodium concentration on the inside of the epithelial cell is equal to that outside the basolateral membrane b. Sodium concentration is higher on the inside of the epithelial cell than on the outside of the basolateral membrane c. Sodium concentration inside the epithelial cell is lower than sodium concentration in the intestinal lumen d. Sodium concentration inside the epithelial cell is higher than that sodium concentration in the intestinal lumen
Which of the following statements best describes the absorption of glucose? Absorption of glucose requires digestion by aminopeptidases on absorptive epithelial microvilli before absorption of the carbohydrate smaller units such as glucose. Absorption of glucose requires an electrochemical gradient of high extracellular K+ set up by primary active transport. Absorption of glucose occurs at villi and crypts mainly in the duodenum where amylases break down carbohydrates into glucose. Absorption of glucose occurs at the transporting epithelia in the small intestine and is a secondary active transport that requires a Na+gradient
A chemical called ouabain inhibits the Na/K ATPase (the sodium-potassium pump). What would happen to glucose concentrations in the extracellular fluid (not the gut lumen) after exposure to ouabain, and why? Ouabain would cause intracellular sodium levels to rise, which would reduce the active transport of glucose from the gut, thereby decreasing glucose in the extracellular fluid. Ouabain would cause extracellular sodium levels to rise, which would reduce the active transport of glucose from the gut, thereby decreasing glucose in the extracellular fluid. Ouabain would cause intracellular sodium levels to rise, which would reduce the active transport of glucose from the cell to the extracellular fluid. Ouabain would cause intracellular sodium levels to rise, which would enhance the active transport of glucose from the gut, thereby increasing glucose in the extracellular fluid.
The transport of nutrients into a cell (think glucose and amino acids, for example) is a crucial physiologic function that is facilitated by different types of membrane transport proteins. These independent transporters work together by different mechanisms to both transport essential molecules into the cell and also maintain the gradients that act as a driving force for this “active transport”. In the intestines, glucose transport occurs across the apical membrane and is then transported across the basolateral membrane into the plasma. In a simplified system, imagine that there are 3 components: • A 2Na+ / 1 Glucose symporter • A glucose uniporter • A 3Na+ / 2K+ ATPase pump / antiporter. Cellular [K+] = 139 mM and [Na+] = 12mM Blood [K+] = 4mm and [Na+] = 145mM 1)Draw a representative cell with the expected polarity and populate it with the position of the expected transporters. 2)Carefully explain the direction of ion/molecule movement and what the driving forces are and how…
Polyethylene glycol (PEG) is a solute that is consumed in order to "clean out" the digestive tract in preparation for a colonoscopy. PEG cannot enter intestinal cells as there is no transport mechanism for it. How would this affect the absorption of water into the small intestine? (assume that it is taken at the correct dose and you are not actually reversing the concentration gradient across the intestinal cells.) Explain your answer in terms of concentration gradients.
When blood glucose level rises, the pancreas secretes insulin, and as a result blood glucose level declines. When blood glucose level is low, the pancreas secretes glucagon, and as a result blood glucose level rises. Such regulation of blood glucose level is the result of A reproduction thermal regulation community homeostasis 2,279 12 tv N MacBook Air DII DD F1 F2 F3 F4 F5 F6 F7 F8 F9 F10 F1 @ %23 24 2 6. %3D * CO
Which is not a type of endocytotic vesicular transport? a. engulfment of microorganismsb. nutrient absorption of intestinal cellsc. neurotransmitter released. insulin uptakee. none of the above
Sodium/glucose cotransporters on intestinal cells move glucose from the intestinal lumen (low glucose concentration) to inside the cell (high glucose concentration). Which of the following would increase the rate of glucose transport into the cell? a. Increase the intracellular glucose concentration. b. Decrease the extracellular glucose concentration. c. Decrease the extracellular Na+ concentration. d. Increase the extracellular Na+ concentration.
When LDL (low density lipoprotein) is taken up by cells during pinocytosis, all of the following steps in the processing of LDL and its receptor protein occur, with the exception of: LDL is digested in lysosomes, releasing cholesterol to the cytoplasm LDL receptors are digested in the lysosomes along with the LDL LDL attaches to LDL receptors, which form clathrin-coated vesicles the endosomes fuse with lysosomes for digestion of the LDL the vesicles fuse with endosomes, and LDL receptors are recycled