it is known that exercise is good for diabetics. explain how GLUT 4 transporters may be involved in this beneficial effect of exercise.
Glucose is an important fuel for contracting muscle. The metabolism of normal glucose is vital for health. The most important stimulators of glucose transport in skeletal muscle are insulin and exercise. The major cellular mechanism that diminishes blood glucose when carbohydrates are ingested is insulin-stimulated glucose transport into skeletal muscle. Skeletal muscle both stores glucose as glycogen and oxidizes it to produce energy. The main glucose transporter protein that mediates this uptake is GLUT4. It plays a major role in regulating whole body glucose homeostasis.
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