Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 5, Problem 2EQ
Discuss the types of experimental observations that Mary Lyon brought together in proposing her hypothesis concerning X-chromosome inactivation. In your own words, explain how these observations were consistent with her hypothesis.
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Chapter 5 Solutions
Genetics: Analysis and Principles
Ch. 5.1 - A female snail that coils to the left has...Ch. 5.1 - 2. What is the molecular explanation for maternal...Ch. 5.2 - 1. In fruit flies, dosage compensation is achieved...Ch. 5.2 - 2. According to the Lyon hypothesis,
a. one of...Ch. 5.2 - Prob. 3COMQCh. 5.3 - 1. In mice, the copy of the Igf2 gene that is...Ch. 5.3 - 2. A female mouse that is is crossed to a male...Ch. 5.3 - Prob. 3COMQCh. 5.3 - Prob. 4COMQCh. 5.4 - 1. Extranuclear inheritance occurs due to
a....
Ch. 5.4 - 2. A cross is made between a green four-o’clock...Ch. 5.4 - 3. Some human diseases are caused by mutations in...Ch. 5.4 - 4. Chloroplasts and mitochondria evolved from an...Ch. 5 - Define the term epigenetic inheritance, and...Ch. 5 - 2. Describe the inheritance pattern of maternal...Ch. 5 - A maternal effect gene exists in a dominant N...Ch. 5 - 4. A Drosophila embryo dies during early...Ch. 5 - 5. For Mendelian inheritance, the nuclear genotype...Ch. 5 - Suppose a maternal effect gene exists as a...Ch. 5 - Suppose that a gene affects the anterior...Ch. 5 - Explain why maternal effect genes exert their...Ch. 5 - As described in Chapter 22, researchers have been...Ch. 5 - 10. With regard to the numbers of sex chromosomes,...Ch. 5 - 11. What is a Barr body? How is its structure...Ch. 5 - Among different species, describe three distinct...Ch. 5 - 13. Describe when X-chromosome inactivation occurs...Ch. 5 - 14. Describe the molecular process of X-chromosome...Ch. 5 - Prob. 15CONQCh. 5 - 16. How many Barr bodies would you expect to find...Ch. 5 - 17. Certain forms of human color blindness are...Ch. 5 - A black female cat (XBXB) and an orange male cat...Ch. 5 - Prob. 19CONQCh. 5 - When does the erasure and reestablishment phase of...Ch. 5 - In what types of cells would you expect de novo...Ch. 5 - 22. On rare occasions, people are born with a...Ch. 5 - Genes that cause Prader-Willi syndrome and...Ch. 5 - Prob. 24CONQCh. 5 - What is extranuclear inheritance? Describe three...Ch. 5 - Prob. 26CONQCh. 5 - Among different species, does extranuclear...Ch. 5 - Extranuclear inheritance often correlates with...Ch. 5 - Prob. 29CONQCh. 5 - Prob. 30CONQCh. 5 - Which of the following traits or diseases is (are)...Ch. 5 - Prob. 32CONQCh. 5 - 33. Describe how a biparental pattern of...Ch. 5 - Figure 5.1 describes an example of a maternal...Ch. 5 - 2. Discuss the types of experimental observations...Ch. 5 - Prob. 3EQCh. 5 - As a hypothetical example, a trait in mice results...Ch. 5 - You have a female snail that coils to the right,...Ch. 5 - Prob. 6EQCh. 5 - 7. Figure 5.6 describes the results of...Ch. 5 - Prob. 8EQCh. 5 - In the experiment of Figure 5.6, why does a clone...Ch. 5 - Prob. 10EQCh. 5 - 11. A variegated trait in plants is analyzed using...Ch. 5 - 1. Recessive maternal effect genes are identified...Ch. 5 - Prob. 2QSDC
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- "While other proteins come and go during the cell cycle, the proteins of the origin recognition complex remain bound to the DNA throughout" is true or false.arrow_forwardA cytogeneticist is studying the cells from an abnormal female monkey. In some cells, she finds that both X-chromosomes are active (i.e. not packaged into a Barr body), although one of the X-chromosomes appears shorter. She also finds that one of the autosomes are packaged as a Barr body, and she suspects that a translocation event might have been involved. By referring to the mechanism of X-chromosome inactivation, explain the observations made by the scientistarrow_forwardIf you were to design an experiment to get p53 back into cancer cells, how would you go about that work? How would you direct p53 into the nucleus of cancer cells without directing it to the nucleus of healthy cells? As an overabundance of p53 in healthy cells would cause problems. Could someone in depth answer these questions for me and explain them cellularly.arrow_forward
- How three-point crosses verify Sturtevant’s map of the Drosophila X chromosome.arrow_forwardOccasionally, a mouse X chromosome is broken into two pieces and each piece becomes attached to a different autosome. A scientist studies this cell, and finds that the genes on only one of the two pieces undergo inactivation. By referring to the mechanism of X-chromosome inactivation, explain the observation made by the scientist.arrow_forwardTrue or false Oncogenes are gene that are normally not found in a cell and must be introduced into the DNA by some mechanism, such as a viral infection.arrow_forward
- In the past, the IOC has employed two genetic sex- determination tests. The Barr body test screens for the presence of two X chromosomes. In XX somatic cells, one copy of the X chromosome condenses into a largely inactive structure called a Barr body, which can be seen using a light microscope. In more recent years, a polymerase chain reaction-based screen has been used to amplify the DNA sequence of the SRY gene, which is found only on the Y chromosome. Based on their karyotypes, what would be the outcome of these two tests for each of the four individuals? Drag the labels to indicate the presence or absence of a Barr body and the SRY gene sequence.arrow_forward“In an organism that reproduces asexually, there is no difference between a somatic cell mutation and a germ line mutation.” Is this statement true? Explain.arrow_forwardWhy would a mutation in a somatic cell of a multicellular organism not necessarily result in a detectable phenotype?arrow_forward
- Briefly explain how McClintock determined that D s was occasionallymoving from one chromosomal location to another. Discussthe type of data she examined to arrive at this conclusion.arrow_forwardhttp://www.letsgethealthy.org/students/games/epigenetics-game/ (Links to an external site.) For the assignment this week I want you to play this epigenetic game that will show you how your choices (which will be the equivalent of of external factors in someone life) make your genes act differently. Last week, we learned about biology and race and how these fit together in the formation of biological determinants and social misconceptions. For this week's discussion, play the game. Discuss with your classmates what happened, and what you have learned about epigenetics and how this changes your understanding of genetics . How do epigenetic changes and epigenetic mechanisms in general influence health, our concepts of race, and inequality?arrow_forwardWhich of the following statements regarding X-inactivation is TRUE?(posted) Inactivated X chromosomes are only found in somatic cells of females. After X-inactivation happens in a cell, all daughter cells resulting from mitotic events of that cell will have the same X chromosome ina none of the statements listed here are true X-inactivation is a random event that happens during human development right before a fetus is born. all of the statements listed here are true)arrow_forward
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