Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 5, Problem 2CONQ
Describe the inheritance pattern of maternal effect genes. Explain how the maternal effect occurs at the cellular level. What are the expected functional roles of the proteins that are encoded by maternal effect genes?
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Describe the inheritance pattern of maternal effect genes. Explainhow the maternal effect occurs at the cellular level. What are theexpected functional roles of the proteins that are encoded bymaternal effect genes?
Talk about the challenges involved in determining the genetic components of polygenic illnesses.
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Hereditary illnesses of genomic instability include Werner syndrome, Bloom syndrome, XP, ataxia-telangiectasia, and Fanconi anemia. Which of these ailments has molecular mechanisms behind it? Which kind of genetic instability is connected to which disorder?.
Name two ways in which loss of p53 function contributes to a malignant phenotype. Explain how benzo(a) pyrene can cause loss of p53 function.
Hint: Loss of p53 function occurs in the majority of human tumors.
Chapter 5 Solutions
Genetics: Analysis and Principles
Ch. 5.1 - A female snail that coils to the left has...Ch. 5.1 - 2. What is the molecular explanation for maternal...Ch. 5.2 - 1. In fruit flies, dosage compensation is achieved...Ch. 5.2 - 2. According to the Lyon hypothesis,
a. one of...Ch. 5.2 - Prob. 3COMQCh. 5.3 - 1. In mice, the copy of the Igf2 gene that is...Ch. 5.3 - 2. A female mouse that is is crossed to a male...Ch. 5.3 - Prob. 3COMQCh. 5.3 - Prob. 4COMQCh. 5.4 - 1. Extranuclear inheritance occurs due to
a....
Ch. 5.4 - 2. A cross is made between a green four-o’clock...Ch. 5.4 - 3. Some human diseases are caused by mutations in...Ch. 5.4 - 4. Chloroplasts and mitochondria evolved from an...Ch. 5 - Define the term epigenetic inheritance, and...Ch. 5 - 2. Describe the inheritance pattern of maternal...Ch. 5 - A maternal effect gene exists in a dominant N...Ch. 5 - 4. A Drosophila embryo dies during early...Ch. 5 - 5. For Mendelian inheritance, the nuclear genotype...Ch. 5 - Suppose a maternal effect gene exists as a...Ch. 5 - Suppose that a gene affects the anterior...Ch. 5 - Explain why maternal effect genes exert their...Ch. 5 - As described in Chapter 22, researchers have been...Ch. 5 - 10. With regard to the numbers of sex chromosomes,...Ch. 5 - 11. What is a Barr body? How is its structure...Ch. 5 - Among different species, describe three distinct...Ch. 5 - 13. Describe when X-chromosome inactivation occurs...Ch. 5 - 14. Describe the molecular process of X-chromosome...Ch. 5 - Prob. 15CONQCh. 5 - 16. How many Barr bodies would you expect to find...Ch. 5 - 17. Certain forms of human color blindness are...Ch. 5 - A black female cat (XBXB) and an orange male cat...Ch. 5 - Prob. 19CONQCh. 5 - When does the erasure and reestablishment phase of...Ch. 5 - In what types of cells would you expect de novo...Ch. 5 - 22. On rare occasions, people are born with a...Ch. 5 - Genes that cause Prader-Willi syndrome and...Ch. 5 - Prob. 24CONQCh. 5 - What is extranuclear inheritance? Describe three...Ch. 5 - Prob. 26CONQCh. 5 - Among different species, does extranuclear...Ch. 5 - Extranuclear inheritance often correlates with...Ch. 5 - Prob. 29CONQCh. 5 - Prob. 30CONQCh. 5 - Which of the following traits or diseases is (are)...Ch. 5 - Prob. 32CONQCh. 5 - 33. Describe how a biparental pattern of...Ch. 5 - Figure 5.1 describes an example of a maternal...Ch. 5 - 2. Discuss the types of experimental observations...Ch. 5 - Prob. 3EQCh. 5 - As a hypothetical example, a trait in mice results...Ch. 5 - You have a female snail that coils to the right,...Ch. 5 - Prob. 6EQCh. 5 - 7. Figure 5.6 describes the results of...Ch. 5 - Prob. 8EQCh. 5 - In the experiment of Figure 5.6, why does a clone...Ch. 5 - Prob. 10EQCh. 5 - 11. A variegated trait in plants is analyzed using...Ch. 5 - 1. Recessive maternal effect genes are identified...Ch. 5 - Prob. 2QSDC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are the possible genotypes of the PTC locus?arrow_forwardLoss of p53 function occurs in the majority of human tumors. Name two ways in which loss of p53 function contributes to a malignant phenotype. Explain how benzo(a) pyrene can cause loss of p53 function.arrow_forwardExplain how the same gen can be highly expressed in several distinct tissues (e.g. brain, liver, and lung) of an organism, yet silent in all other tissues. Hint: The answer is not that they share the same tissue-specific transcription factors..arrow_forward
- What are the major factors in the various mutants of the spike protein?arrow_forwardDescribe how polymorphisms is found at 13910-C/T and 22018-G/A in the regulatory area of the lactase gene (LCT). And elaborate the mechanism for two polymorphisms causing mutation from 13910-C/T and 22018-G/A to 13910-C/C or 22018-G/G variants in lactase intolerance disorder. also, how LCT gene is corelated to lactase intolerance disorder?arrow_forwardBriefly describe the effects of colchicine treatment on cells. What are the genetic implications of such effects?arrow_forward
- Our understanding of maternal effect genes has been greatly aided by their identification in experimental organisms such as Drosophila melanogaster and Caenorhabditis elegans. In experimental organisms with a short generation time, geneticists have successfully searched for mutant alleles that prevent the normal process of embryonic development. In many cases, the offspring die at early embryonic or larval stages. These are called maternal effect lethal alleles. How would a researcher identify a mutation that produced a recessive maternal effect lethal allele?arrow_forwardThe phenotype of a heterozygous mouse (Aa) is agouti. The agouti banding pattern is due to altered expression of the agouti gene. Which of the following statement is false? a) Expression of the agouti gene inhibits the production of eumelanin. b) Evidence suggests that the agouti gene is only expressed in tissues associated with fur production. c) Epigenetic markers silence the agouti gene resulting in dark pigmentation at the tip and root of the hair. d) All of the abovearrow_forwardDescribe and compare the structural features of Ig genesuperfamily constant and variable domains.arrow_forward
- Protein levels and mRNA levels for a particualr gene don’t always match. For example, the GCN4 gene in yeast is always producing mRNA, but the Gcn4 protein is only made when the cells are starved. What does this mean for diagnostic techniques that try to look at gene expression?arrow_forwardAlpha-1 antitrypsin has codominant inheritance. M genes express normal levels. S and Z genes have low expression. Which of the following is most likely to develop emphyema? A person with: 1) two M genes who does smoke 2) two S genes who does smoke 3) one M and one S gene who does not smoke 4) one M gene and one S gene who does smoke 5) two M genes who does not smoke 6) two S genes who does not smokearrow_forwardIdentify the two general functions of the proteins encoded bytumor-suppressor genes.arrow_forward
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