Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 4, Problem 46P
The ancestry of a white female tiger bred in a city zoo is depicted in the pedigree following part (e) of this problem. White tigers are indicated with unshaded symbols. (As you can see, there was considerable inbreeding in this lineage. For example, the white tiger Mohan was mated with his daughter) In answering the following questions, assume that white is determined by allelic differences at a single gene and that the trait is fully penetrant. Explain your answers by citing the relevant information in the pedigree.
a. | Could white coat color be caused by a Y-linked allele? |
b. | Could white coat color be caused by a dominant X-linked allele? |
c. | Could white coat color be caused by a dominant autosomal allele? |
d. | Could white coat color be caused by a recessive X-linked allele? |
e. | Could white coat color be caused by a recessive autosomal allele? |
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
In a dihybrid cross of two bi-allelic Mendelian genes, A (two alleles – completely dominant A and recessive a), and B (two alleles – completely dominant B and recessive b), such that the parental generation comprises of pure-bred homozygotes (i.e. AABB with aabb), what are the expected genotype and phenotype ratios in the F1 and F2, if the F1 cross is (a) an intercross and if the F1 cross is (b) a testcross
The pedigree concerns eye phenotypes in Tribolium beetles. The solid symbols represent black eyes, the open symbols represent
brown eyes, and the cross symbols (X) represent the "eyeless" phenotype, in which eyes are totally absent.
Assume that these three phenotypes are the result of three alleles of a single gene, E, where E' is black, g? is brown, and
is eyeless.
Assign a genotype to each individual in generation II.
1
2
3
II
4
7
8
II
9
10 | 11
12
IV
13
Grifths, et al, Introduction to Genetic Analysis 12e
© 2020 Macmillan Leaning
Answer Bank
E'?
E'E
What is the mode of inheritance of the eyeless phenotype?
autosomal dominant
X-linked recessive
X-linked dominant
autosomal recessive
CO
In the following pedigree, filled circles or squares indicate affected individuals. Write your answers based on this.
a. Does the following pedigree suggest mitochondrial inheritance? Why or why not?
b. What other mode(s) of inheritance is (are) consistent with these data?
c. How could you distinguish between mitochondrial inheritance and any other possibility that is consistent with the data?
Chapter 4 Solutions
Genetics: From Genes to Genomes
Ch. 4 - Choose the best matching phrase in the right...Ch. 4 - Humans have 46 chromosomes in each somatic cell....Ch. 4 - The figure that follows shows the metaphase...Ch. 4 - Human XX males who are sex-reversed because they...Ch. 4 - Researchers discovered recently that the sole...Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Indicate which of the cells numbered iv matches...Ch. 4 - a. What are the four major stages of the cell...Ch. 4 - Answer the questions that follow for each stage of...Ch. 4 - Can you think of anything that would prevent...
Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Which types of cell division mitosis, meiosis I,...Ch. 4 - Complete the following statements using as many of...Ch. 4 - The five cells shown in figure a e are all from...Ch. 4 - One of the first microscopic observations of...Ch. 4 - A person is simultaneously heterozygous for two...Ch. 4 - Assuming i that the two chromosomes in every...Ch. 4 - In the moss Polytrichum commune, the haploid...Ch. 4 - Can you think of anything that would prevent...Ch. 4 - Sister chromatids are held together through...Ch. 4 - The pseudoautosomal regions PARs of the X and Y...Ch. 4 - Remarkably, the platypus has 10 sex chromosomes,...Ch. 4 - Somatic cells of chimpanzees contain 48...Ch. 4 - In humans: a. How many sperm develop from 100...Ch. 4 - Women sometimes develop benign tumors called...Ch. 4 - In a certain strain of turkeys, unfertilized eggs...Ch. 4 - Imagine you have two pure-breeding lines of...Ch. 4 - A system of sex determination known as...Ch. 4 - In Drosophila, the autosomal recessive brown eye...Ch. 4 - Barred feather pattern is a Z-linked dominant...Ch. 4 - When Calvin Bridges observed a large number of...Ch. 4 - In a vial of Drosophila, a research student...Ch. 4 - In 1919, Calvin Bridges began studying an X-linked...Ch. 4 - In Drosophila, a cross was made between a...Ch. 4 - As we learned in this chapter, the white mutation...Ch. 4 - The following is a pedigree of a family in which a...Ch. 4 - Each of the four pedigrees that follow represents...Ch. 4 - The pedigree that follows indicates the occurrence...Ch. 4 - Duchenne muscular dystrophy DMD is caused by a...Ch. 4 - The X-linked gene responsible for DMD encodes a...Ch. 4 - Males have hemophilia when they are hemizygous for...Ch. 4 - In the Fast Forward Box Visualizing X Chromosome...Ch. 4 - Consider the following pedigrees from human...Ch. 4 - Several different antigens can be detected in...Ch. 4 - The ancestry of a white female tiger bred in a...Ch. 4 - The pedigree that follows shows the inheritance of...Ch. 4 - In 1995, doctors reported a Chinese family in...Ch. 4 - In cats, the dominant O allele of the X-linked...Ch. 4 - In marsupials like the opposum or kangaroo, X...Ch. 4 - The pedigree diagram below shows a family in which...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A recessive maternal effect mutant in zebrafish, called ichabod, results in embryos lacking heads that are non-viable. You have been instructed to identify females that are homozygous for the ichabod mutant allele. At your disposal are a tank of wild-type fish (males and females), a tank of male and female parental fish that are all heterozygous for the ichabod mutant allele (ichabod/+), and a tank of F1 fish derived from a cross between a heterozygous male and heterozygous female (ichabod/+). Which of the following would be a way to identify females that are homozygous mutant, i.e. ichabod/ichabod? Select all answers that would work.arrow_forwardA female animal with genotype A/a ⋅ B/b is crossed with a double-recessive male (a/a ⋅ b/b). Their progeny include 442 A/a ⋅ B/b, 458 a/a ⋅ b/b, 46 A/a ⋅ b/b, and 54 a/a ⋅ B/b. Explain these results.arrow_forwardIn dogs, dark coat color phenotype (D) is dominant over albino (a) and short hair (S) is dominant over long hair (1). Assume that these phenotypes are caused by two independently assorting genes and write as much as you can, the genotypes of the parents in the cross below. D, a, S and I represent phenotypes Y indicates the presence of progeny with this phenotype , whereas N indicates the absence of progeny with this phenotype PARENTS PHENOTYPES TYPES of PROGENY PHENOTYPE D,S D,I a,S a,l D,S X a,l Y Yarrow_forward
- Basic body color for horses is influenced by several genes, one of which has several different alleles, Two of these alleles—the chestnut (dark brown) allele and a diluting (pale cream) allele (often incorrectly called ‘albino’) - display incomplete dominance. A horse heterozygous for these two alleles is a palomino (golden body color with flaxen mane and tail). Is it possible to produce a herd of pure-breeding palomino horses? Why or why not? Work test cross for mating a palomino to a palomino and predict the phenotypic ratio among their offspringarrow_forwardTwo fruit flies (Drosophila melanogaster) were crossed. The cross was between a homozygous red-eyed, wingless female and a white-eyed male heterozygous for wings. Recall that red eyes (R) is dominant over white eyes (r) and is inherited on the X chromosome (sex-linked) and as such, eye colour alleles should be written as superscript. In addition, the autosomal trait wings (W) is dominant over wingless (w). 1. List the female genotype 2. List the male genotype 3. Construct a Punnett Square for this dihybrid cross on a piece of paper, to determine what the offspring of such a cross would be with respect to sex, eye colour & wings. 4. Using the information from your Punnett Square answer the following: a. What genotypes did you get (list all genotype combinations; if you have more than one of the same kind, you do NOT have to re-list it.) b. What are the phenotypic ratios of the offspring with respect to sex, eye colour and wings?arrow_forwardThe wild-type (W) Abraxas moth has large spots on its wings, but the lacticolor (L) form of this species has very small spots. Crosses were made between strains differing in this character, with the following results:Provide a clear genetic explanation of the results in these two crosses, showing the genotypes of all individual moths.arrow_forward
- A recessive maternal effect mutant in zebrafish, called ichabod, results in embryos lacking heads that are non-viable. You have been instructed to identify females that are homozygous for the ichabod mutant allele. At your disposal are a tank of wild-type fish (males and females), a tank of male and female parental fish that are all heterozygous for the ichabod mutant allele (ichabodl+), and a tank of F1 fish derived from a cross between a heterozygous male and heterozygous female (ichabodl+). Which of the following would be a way to identify females that are homozygous mutant, i.e. ichabodlichabod? Select all answers that would work. Cross F1 females to F1 males and observe their offspring. Crosses that produce headless offspring came from a homozygous female. a. Cross F1 males to females from the parental tank and observe their offspring. 25% of these crosses should produce headless offspring. b. Cross F1 females to F1 males to make the F2 generation. Cross F2 females to F2 males and…arrow_forwardIn the shorthorn breed of cattle, The red and white coat colors are codominant with each other with the resulting hit rosagas condition being roan. A breeder has some white, some Roan, and some red cattle (female) And only one round bull (male).  A. What color cow would be bread to the ro bowl to guarantee the best chance of having white offspring? B. What is the probability of a red cow cross with the Roan bull resulting in a white half? explain by using parent and possible offspring genotypes.  C. What is one possible way that the farmer can guarantee having over red offspring by going outside of his breeding stock? Explain by using parent and possible offspring genotypes. arrow_forwardCoat color in mice (Mus musculus) can show many varieties. You have two true-breeding mouse stains, one with white fur; the other with black fur. Upon crossing a male and female of both strains, you find that all of the offspring show the agouti coat color: agouti is best described as a layered brown color (think of the normal coat color of squirrels and rabbits). Upon crossing agouti males and females, you observe the following traits: 450 agouti mice, 150 mice with black fur, and 200 mice with white fur; reciprocal crosses yield similar results. A. Are these results (the F1 and F2) best explained by one gene with three alleles or two genes, each with two alleles? Explain your answer with text and by using allele symbols to represent the F1 and F2 results. B. What genotypes are associated with each trait? C. What phenomenon is occurring in this scenario? Explain your answer.arrow_forward
- On the basis of Mendel’s observations (i.e. Mendelian patterns), predict the results from the following crosses with peas. Show the results in terms of genotypes, phenotypes, and their proportions in the offspring. The progeny of a tall (dominant and homozygous) variety crossed with a dwarf variety. The progeny of (a) self-fertilized. The progeny from (a) crossed with the original tall parent. The progeny of (a) crossed with the original dwarf parent.arrow_forwardFrom a cross (Xyz) / (xYZ) x (xyz) / (xyz), where X,x, Y,y and Z,z represent alleles of three linked genes whose relative order is unknown, the least frequent classes of progeny are genotype (xyz) / (xyz) and (XYZ) / (xyz). What is the correct relative order of genes X, Y and Z? Answer using lowercase letters separated by a dash (-). Example: x-y-zarrow_forwardThree genes in fruit flies affect a particular trait, and at least one dominant allele of each gene is necessary to get a wild-type phenotype. a. What phenotypic ratio would you predict among the progeny if you crossed triply heterozygous flies? b. You cross a particular wild-type male in succession with three tester strains. In the cross with one tester strain (AA bb cc), only 1/4 of the progeny are wild type. In the crosses involving the other two tester strains (aa BB cc and aa bb CC), half of the progeny are wild type. What is the genotype of the wild-type male? (Pls help asap!!)arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY