Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 4, Problem 15P
One of the first microscopic observations of chromosomes in cell division was published in 1905 by Nettie Stevens. Because it was hard to reproduce photographs at the time, she recorded these observations as camera lucida sketches. One such drawing, of a completely normal cell division in the mealworm Tenebrio molitor, is shown here. The techniques of the time were relatively unsophisticated by today’s standards, and they did not allow her to resolve chromosomal structures that must have been present.
| a. | Describe in as much detail as possible the kind of cell division and the stage of division depicted in the drawing. |
| b. | What chromosomal structure(s) cannot be resolved in the drawing? |
| c. | How many chromosomes are present in normal Tenebrio molitor gametes? |
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In order to investigate the cell cycle in HEK293 cells in culture, I ran a flow cytometry experiment. I labeled their nuclei with DAPI to analyze DNA content. In these flow cytometry plots below, label the two main phases of the cell cycle that you can see. Briefly, explain your answer.
1) What phase of mitosis is this?
Answer:
2) What is the indicated structure 1? select one.
a. chromosome
b. chromosome with two sister chromatids
c. centrioles/centrosome
d. spindle fibres
e. metaphase plate
3)If the diploid (2n) number of this cell is 8 how many chromosomes are present?
4) If the diploid (2n) number of this cell is 8 how many sister chromatids are present?
5) If the diploid (2n) number of this cell is 8 how many homologous pairs are present?
Why do eukaryotic cells need to go through the elaborate procedure of mitosis rather than simply dividing during interphase? Select as many answers as apply.
1.Daughter cells must be genetically identical to the mother cell, for homeostasis and ordered tissue growth.
2.Bivalent chromosomes must condense and be separated in an orderly fashion, to allow equal distribution of copies into daughter cells
3.Physically dividing the nucleus during interphase would likely lead to gross chromosome breakage and highly unequal assortment of genetic information into daughter cells.
4.Dividing the nucleus during interphase would have the same outcome as mitosis
5.Daughter cells must have half the number of chromosomes after mitosis than the mother cells
6.The homologous pairs of chromosomes need to be separated, to ensure copies go to the daughter cells.
Chapter 4 Solutions
Genetics: From Genes to Genomes
Ch. 4 - Choose the best matching phrase in the right...Ch. 4 - Humans have 46 chromosomes in each somatic cell....Ch. 4 - The figure that follows shows the metaphase...Ch. 4 - Human XX males who are sex-reversed because they...Ch. 4 - Researchers discovered recently that the sole...Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Indicate which of the cells numbered iv matches...Ch. 4 - a. What are the four major stages of the cell...Ch. 4 - Answer the questions that follow for each stage of...Ch. 4 - Can you think of anything that would prevent...
Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Which types of cell division mitosis, meiosis I,...Ch. 4 - Complete the following statements using as many of...Ch. 4 - The five cells shown in figure a e are all from...Ch. 4 - One of the first microscopic observations of...Ch. 4 - A person is simultaneously heterozygous for two...Ch. 4 - Assuming i that the two chromosomes in every...Ch. 4 - In the moss Polytrichum commune, the haploid...Ch. 4 - Can you think of anything that would prevent...Ch. 4 - Sister chromatids are held together through...Ch. 4 - The pseudoautosomal regions PARs of the X and Y...Ch. 4 - Remarkably, the platypus has 10 sex chromosomes,...Ch. 4 - Somatic cells of chimpanzees contain 48...Ch. 4 - In humans: a. How many sperm develop from 100...Ch. 4 - Women sometimes develop benign tumors called...Ch. 4 - In a certain strain of turkeys, unfertilized eggs...Ch. 4 - Imagine you have two pure-breeding lines of...Ch. 4 - A system of sex determination known as...Ch. 4 - In Drosophila, the autosomal recessive brown eye...Ch. 4 - Barred feather pattern is a Z-linked dominant...Ch. 4 - When Calvin Bridges observed a large number of...Ch. 4 - In a vial of Drosophila, a research student...Ch. 4 - In 1919, Calvin Bridges began studying an X-linked...Ch. 4 - In Drosophila, a cross was made between a...Ch. 4 - As we learned in this chapter, the white mutation...Ch. 4 - The following is a pedigree of a family in which a...Ch. 4 - Each of the four pedigrees that follow represents...Ch. 4 - The pedigree that follows indicates the occurrence...Ch. 4 - Duchenne muscular dystrophy DMD is caused by a...Ch. 4 - The X-linked gene responsible for DMD encodes a...Ch. 4 - Males have hemophilia when they are hemizygous for...Ch. 4 - In the Fast Forward Box Visualizing X Chromosome...Ch. 4 - Consider the following pedigrees from human...Ch. 4 - Several different antigens can be detected in...Ch. 4 - The ancestry of a white female tiger bred in a...Ch. 4 - The pedigree that follows shows the inheritance of...Ch. 4 - In 1995, doctors reported a Chinese family in...Ch. 4 - In cats, the dominant O allele of the X-linked...Ch. 4 - In marsupials like the opposum or kangaroo, X...Ch. 4 - The pedigree diagram below shows a family in which...
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- The figure above shows a metaphase in which one chromosome is only connected to the spindle by a single kinetochore, thus the sister chromatids may not separate correctly during anaphase. which of the following statement/s is/are correct;arrow_forward1). A diploid somatic cell from a dog (Canis lupus familiaris) has a total of 78 chromosomes (2n = 78). As in humans, sex chromosomes determine sex: XX in females and XY in males. a) What is the total number of DNA molecules in G2 of the cell cycle? b) What is the total number of sister chromatids during prometaphase? c) What is the total number of telomeres in a somatic dog cell in G1? d) What is the total number of autosomes?arrow_forwardYou are looking at a spread of cells in some unknown stage of cell division, and you discover that there are seven chromosomes (3 metacentric, 3 telocentric, and 1 acrocentric) visible in each dividing cell. What type of nuclear division have you identified, and what conclusions can be drawn about the number of chromosomes that make-up the species?arrow_forward
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- Draw a diagram of the cell cycle and label the phases. On your diagram: a) For each phase, indicate whether the chromosomes are condensed or not. b) Indicate the phase(s) when it is possible to do a karyotype c) Indicate the phase-transition(s) where the cell would arrest if you add hydroxyurea.arrow_forward4) What is occurring during the Anaphase stage of mitosis, such as is shown in the figure to the right? A) The DNA is being replicated. B) The homologous chromosomes are separating. C) Sister chromatids are being pulled to opposite poles. D) A cleavage furrow is forming to divide the cell. Inid parents made gametes usingarrow_forwardWhich of the following statements are true regarding mitosis in humans?arrow_forward
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