Concept explainers
a.
To determine: The frequency of recombinants (RF).
Introduction: A heterozygous is a trait when dissimilar kinds of two alleles combine to form a feature. In this type, dominant and recessive alleles are present in the pair, and the dominant will signify the type of trait the offspring will show.
b.
To determine: The uncorrected map distance, based on RF.
Introduction: A linkage map is a table for a species or investigational population that displays the position of its known genes or genetic markers comparative to each other in terms of recombination frequency, rather than a particular physical distance along each chromosome.
c.
To determine: The corrected map distance, based on tetrad frequencies.
Introduction: Genetic distance is a extent of the genetic deviation between species or between populations within a species, whether the length measures the time from a common ancestor or degree of variation.
d.
To determine: The corrected map distance, based on the mapping function
Introduction: Genetic maps are constructed by recombination frequencies since both odd and even numbers of crossovers can take place between any two gene loci, as the physical distance between two loci rises, the maximum recombination frequency levels off at 50%.
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Introduction to Genetic Analysis
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- Consider the cross RrmmTT x RRMmTt. Assume the three gene pairs are independently segregating. a. Derive the gametic ratio of the second parent using the branching method.b. Derive the genotypic ratio for the offspring from each cross using the branching method. Showcomplete solutions.c. What is the probability that an offspring from this cross will be heterozygous for all gene pairs?arrow_forwardConsider the first category of test-cross offspring shown in figure 8.2 (+b, LS). Consider also that the parents of the heterozygous female flies in the test cross had the following genotypes: bb, SS, and +, LL. A. What would be the physical phenotype of these flies? B. If PCR was conducted with the DNA of one of these flies using the primers for the molecular marker, what would be the appearance of the bands on an electrophoresis gel with the PCR products? C. If the gene for black body and the locus for the molecular marker (L long or S short) were unlinked, what proportion of the test-cross progeny would be black flies that are heterozygous for the molecular marker? What proportion would be flies with normal body color, which are homozygous for one form of the molecular marker? D. If the gene for black body and the locus for the molecular marker were linked, how would the proportion of flies be different?arrow_forwardA dihybrid testcross is made to determine if genes C and D are linked. The results are shown in the table. 1. The chi-square value is the sum for all progeny classes of (observed-expected)2/expected. Using the chi-square test for goodness of fit, calculate the chi-square value to test the null hypothesis that genes C and D are unlinked. What is the chi-square value? 2. Using the chi-square test for goodness of fit, how many degrees of freedom are in this data set? 3. Using table 5.2 find the most accurate range within which the p value falls. 4. What is a reasonable conclusion based on the chi-square analysis?arrow_forward
- A yeast geneticist irradiates haploid cells of a strain that is an adenine-requiring auxotrophic mutant, caused by mutation of the gene ade1. Millions of the irradiated cells are plated on minimal medium, and a small number of cells divide and produce prototrophic colonies. These colonies are crossed individually with a wildtype strain. Two types of results are obtained:(1) prototroph × wild type : progeny all prototrophic(2) prototroph × wild type : progeny 75% prototrophic, 25% adenine-requiring auxotrophsa. Explain the difference between these two types of results.b. Write the genotypes of the prototrophs in each case.c. What progeny phenotypes and ratios do you predict from crossing a prototroph of type 2 by the original ade1auxotroph?arrow_forwardIn autotetraploid Chinese primrose (Primula sinensis L.), the gene controlling stigma color is very near the centromere of the chromosome carrying it. The allele G for green stigma is dominant to g for red stigmas. A homozygous green autotetraploid strain is crossed with a homozygous red autotetraploid strain. a. What is the genotype of the Fl1? b. Show the types of gametes the Fl's may be expected to form and derive the expected proportion of each. Show your solution. c. What phenotypic ratio of green to red is expected if: the Fl's are intercrossed? Show your solution. the Fl's are crossed with red plants? Show your solution. d. If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the Fl be expected to produce? Derive the expected F2 phenotypic ratio.arrow_forwarda. Determine the gene order, the recombination frequency between the adjacent genes, the coefficient of coincidence, and the interference. b. Explain why, in this example, the recombination frequencies are not good estimates of the map distance.arrow_forward
- In corn, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of the corn plants (i.e the tassel) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile corn plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male sterile lines Using the cardboard chips, simulate the crosses indicated below. Give the genotypes and phenotypes of the offsprings in each cross, and properly label the nucleus and the cytoplasm of each individual in the cross Legend male sterile cytoplasm Male fertile cytoplasm FF nucleus Ff nucleus ff nucleus A. Male sterile female x FF male Explain the phenotype of the offspring B. Male sterile female x Ff male Explain the phenotype of the offspringarrow_forwardIn an autotetraploid Chinese primrose (Primula sinensis), the gene controlling stigma color is very near the centromere of the chromosome carrying it. The allele G for green stigma is dominant to g for red stigmas. A homozygous green autotetraploid strain is crossed with a homozygous red autotetraploid strain. a. What is the genotype of the F1? b. Show the types of gametes the F1’s may be expected to form and derive the expected proportion of each. c. What phenotypic ratio of green to red is expected if: 1. The F1’s are intercrossed? 2. The F1’s are crossed with red plants d. If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the F1 be expected to produce? Derive the expected F2 phenotypic ratio.arrow_forwardConsider two loci A and B that are 30 cM apart on chromosome 1 in the fruit fly. A paracentric inversion is found to span about half of the distance between these loci, but not include either A or B. What is the approximate recombination frequency expected for these loci in … flies that are heterozygous for this inversion? RF(A-B) for heterozygous flies is … flies that are homozygous for this inversion? RF(A-B) for homozygous flies is …arrow_forward
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