Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 4, Problem 21.23P
Summary Introduction
To determine: The F1 and the tester not considered to be parental in calculating recombination.
Introduction: A three-point testcross allows one to determine the distance between three alleles and the order in which they are located on the chromosome.
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In a cross between mice the genotypes AB/ab ab/ab, what is the recombination frequency if the progeny numbers are 72 AB/ab, 68 ab/ab, 17 Ab/ab, and 21 aB/ab? The alleles are shown for each chromosome, separated by a slash (/).
A series of three-point testcrosses is made to determine the genetic map order of seven linked allele pairs: A/a, B/b, G/g, H/h, Q/q, R/r, and Y/y.From each cross between a triply heterozygous parent listed below, two recombinant classes were noticed as the least frequent among all 8 progeny classes, and are listed at the right in the table.
A. For each testcross write the genotype of the F1 heterozygous parent.
F1 Parental Phenotype Least frequent F2 Phenotype
1.AHB&ahb AHb & ahB
2.RYh&ryH RYH & ryh
3.BhY&bHy Bhy & bHY
4.qYB&Qyb qYb & QyB
5.AbQ&aBq Abq & aBQ
6.ghR&GHr ghr & GHR
B. Write the unified map order of these genes, showing your reasoning.
In a three-point testcross such as this one, why aren’t the F1 and the tester considered to be parental in calculating recombination? (They are parents in one sense.)
Chapter 4 Solutions
Introduction to Genetic Analysis
Ch. 4 - Prob. 1PCh. 4 - Prob. 5PCh. 4 - Prob. 12PCh. 4 - Prob. 13PCh. 4 - Prob. 14PCh. 4 - Prob. 15PCh. 4 - Prob. 16PCh. 4 - Prob. 17PCh. 4 - Prob. 18PCh. 4 - Prob. 19P
Ch. 4 - Prob. 20PCh. 4 - Prob. 21PCh. 4 - Prob. 21.1PCh. 4 - Prob. 21.2PCh. 4 - Prob. 21.3PCh. 4 - Prob. 21.4PCh. 4 - Prob. 21.5PCh. 4 - Prob. 21.6PCh. 4 - Prob. 21.7PCh. 4 - Prob. 21.8PCh. 4 - Prob. 21.9PCh. 4 - Prob. 21.10PCh. 4 - Prob. 21.11PCh. 4 - Prob. 21.12PCh. 4 - Prob. 21.13PCh. 4 - Prob. 21.14PCh. 4 - Prob. 21.15PCh. 4 - Prob. 21.16PCh. 4 - Prob. 21.17PCh. 4 - Prob. 21.18PCh. 4 - Prob. 21.19PCh. 4 - Prob. 21.20PCh. 4 - Prob. 21.21PCh. 4 - Prob. 21.22PCh. 4 - Prob. 21.23PCh. 4 - Prob. 21.24PCh. 4 - Prob. 21.25PCh. 4 - Prob. 21.26PCh. 4 - Prob. 22PCh. 4 - Prob. 23PCh. 4 - Prob. 24PCh. 4 - Prob. 25PCh. 4 - Prob. 26PCh. 4 - Prob. 27PCh. 4 - Prob. 28PCh. 4 - Prob. 29PCh. 4 - Prob. 30PCh. 4 - Prob. 31PCh. 4 - Prob. 32PCh. 4 - Prob. 33PCh. 4 - Prob. 34PCh. 4 - Prob. 35PCh. 4 - Prob. 36PCh. 4 - Prob. 37PCh. 4 - Prob. 38PCh. 4 - Prob. 38.1PCh. 4 - Prob. 38.2PCh. 4 - Prob. 38.3PCh. 4 - Prob. 38.4PCh. 4 - Prob. 38.5PCh. 4 - Prob. 38.6PCh. 4 - Prob. 38.7PCh. 4 - Prob. 38.8PCh. 4 - Prob. 38.9PCh. 4 - Prob. 38.10PCh. 4 - Prob. 38.11PCh. 4 - Prob. 38.12PCh. 4 - Prob. 38.13PCh. 4 - Prob. 38.14PCh. 4 - Prob. 38.15PCh. 4 - Prob. 38.16PCh. 4 - Prob. 38.17PCh. 4 - Prob. 38.18PCh. 4 - Prob. 38.19PCh. 4 - Prob. 38.20PCh. 4 - Prob. 38.21PCh. 4 - Prob. 38.22PCh. 4 - Prob. 38.23PCh. 4 - Prob. 38.24PCh. 4 - Prob. 39PCh. 4 - Prob. 40PCh. 4 - Prob. 41PCh. 4 - Prob. 42PCh. 4 - Prob. 43PCh. 4 - Prob. 44PCh. 4 - Prob. 45PCh. 4 - Prob. 46PCh. 4 - Prob. 47PCh. 4 - Prob. 48PCh. 4 - Prob. 49PCh. 4 - Prob. 50PCh. 4 - Prob. 51PCh. 4 - Prob. 52PCh. 4 - Prob. 53PCh. 4 - Prob. 54PCh. 4 - Prob. 55PCh. 4 - Prob. 56PCh. 4 - Prob. 57PCh. 4 - Prob. 58PCh. 4 - Prob. 59PCh. 4 - Prob. 60PCh. 4 - Prob. 62PCh. 4 - Prob. 63PCh. 4 - Prob. 64PCh. 4 - Prob. 65PCh. 4 - Prob. 66PCh. 4 - Prob. 67PCh. 4 - Prob. 68PCh. 4 - Prob. 69P
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In a three-point testcross, the nonrecombinant progeny are A+ B+ C+ and a b c. The double- crossover progeny are A+ B+ c and a b C+. Which gene is in the middle and why?arrow_forwardin a cross AaBb X aabb, the following progeny were obtained: AaBb=50 aabb=46 Aabb=7 aaBb=6 What is the recombination frequency between the genes A and B? How far apart are they if they were on the same chromosomearrow_forwardGenes A, B, and C lie at map positions 2.5, 7.5, and 17.5, respectively. In a three-point test cross, you observed 2 double crossovers in a total of 1000 progeny. What is the interference in this region?arrow_forward
- A strain of Neurospora with the genotype H ⋅ I is crossedwith a strain with the genotype h ⋅ i. Half the progeny areH ⋅ I, and the other half are h ⋅ i. Explain how this outcome is possible.arrow_forwardGiven the distance between the orange eye color locus and the STRs, how frequent will you expect to get recombinant progeny with orange eyes? What would the probability of this marriage be producing children with orange eyes?arrow_forwardHow does one set up a punnet square for the following problem? I know the answer is supposed to be 3*1/2*1/4*1/4 = 3/32 but I'm not sure how we get these numbers. Please help!Question: In the self of a polygenic trihybrid R1/r1; R2/r2; R3/r3, use the product and sum rules to calculate the proportion of progeny with just one polygene “dose.”arrow_forward
- In letter B: If the map distance equals the number of recombinant/total of offspring, wouldn't it be 24/806 x 100? Wouldn't we add both recombinants? Can you explain letter C? I don't grasp that concept well. And since I'm using my question already, would you be able to answer D. Thank you!arrow_forwardThe A locus and the D locus are so tightly linked that norecombination is ever observed between them. If Ad/Ad is crossed with aD/aD and the F1 is intercrossed,what phenotypes will be seen in the F2 and in whatproportions?arrow_forwardWhat is the distance between the orange eye color locus and the STRs, how frequent will you expect to get recombinant progeny with orange eyes? What would the probability of this marriage be producing children with orange eyes?arrow_forward
- A three-point testcross is carried out between three linked genes. The resulting nonrecombinant progeny are s+ r+ c+and s r c and the double-crossover progeny are s+ r+ c. Which is the middle locus?arrow_forwardA 3-inch plant was crossed with a 15-inch plant, and all F1 plants were 9 inches. The F2 plants exhibited a “normal distribution,” with heights of 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, and 15 inches. (a) What ratio will constitute the “normal distribution” in the F2? (b) What will be the outcome if the F1 plants are testcrossed with plants that are homozygous for all nonadditive alleles?arrow_forwardIn a particular organism, the A locus and the D locus are so tightly linked that no crossing over is ever observed between them. If an AADD individual is crossed to an aadd individual, what types of gametes will their double-heterozygote F1 offspring produce and in what proportions? Group of answer choices 25% parental and 75% recombinant gametes 75% parental and 25% recombinant gametes 100% parental and 0% recombinant gametes 50% parental and 50% recombinant gametes 0% parental and 100% recombinant gametesarrow_forward
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