Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 27, Problem 11RQ
Summary Introduction

To review:

The concept of MDR (multidrug resistance) efflux pump.

Introduction:

MDR stands for multidrug resistance efflux pumps. MDR pump of Gram-negative issimilar to the ABC export system. The MDR efflux pump acts on a broad range of antibiotics irrespective of the structure. It exists in fungi and bacteria as they develop a defense mechanism against the harmful substance. Grouped by homology, energy source as well as structure, there are seven families of MDRs.

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