Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 26, Problem 22RQ
Summary Introduction

To review:

The common causes of bacterial meningitis and the routes of entry of the pathogen.

Introduction:

Bacterial cells, antibiotics, and drugs cannot enter the brain and the spinal cord due to their inability to cross the blood-brain barrier. The endothelial cells in the blood capillaries of the brain are connected together by the tight junctions that prevent the free passage of molecules and bacteria. Certain bacterial pathogens possess the ability to cross the blood-brain barrier and cause infection.

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