Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 25.1, Problem 3COMQ
Which of the following is not a common explanation for a dominant disorder?
a. Haploinsufficiency
b. A change in chromosome number
c. A gain-of-function mutation
d. A dominant-negative mutation
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Which of the following is associated with chemical modifications to chromosomes that label alleles as coming from the mother or father?
a. Multiple alleles
b. Extranuclear inheritance
c. Epigenetic marks
d. Small non coding RNAs
If two mutational events are sufficient to cause some forms of cancer, what distinguishes familial forms (i.e. those that "run in families") of cancer from spontaneous cases?
A. spontaneous forms inherit both mutations
B. familial forms are caused by chance alone
C. familial forms inherit one mutation
D. there is no difference
E. none of the above
One of the forms of rickets is inherited in the autosomal dominant way. This disease is a result of:
Select one:
a. Aneuploidy.
O b. Changes in the number of chromosomes.
c. Chromosomal mutations.
e. Gene mutations.
O d. Polyploidy.
Chapter 25 Solutions
Genetics: Analysis and Principles
Ch. 25.1 - Which of the following wouldnotbe consistent with...Ch. 25.1 - 2. Assuming complete penetrance, which type of...Ch. 25.1 - 3. Which of the following is not a common...Ch. 25.1 - Prob. 4COMQCh. 25.2 - Prob. 1COMQCh. 25.2 - Haplotype association studies are aimed at the...Ch. 25.3 - 1. Which of the following is not a method used in...Ch. 25.3 - 2. Which of the following prenatal genetic testing...Ch. 25.4 - Prob. 1COMQCh. 25.5 - 1. An oncogene is produced from a ________that has...
Ch. 25.5 - Which of the following is a type of genetic change...Ch. 25.5 - 3. Tumor-suppressor genes promote cancer...Ch. 25.5 - 4. Normal (nonmutant) tumor-suppressor genes often...Ch. 25.5 - Prob. 5COMQCh. 25.6 - Prob. 1COMQCh. 25 - 1. With regard to pedigree analysis, make a list...Ch. 25 - 2. Explain, at the molecular level, why human...Ch. 25 - 3. Many genetic disorders exhibit locus...Ch. 25 - Prob. 4CONQCh. 25 - Prob. 5CONQCh. 25 - Figure 25.1 illustrates albinism in two different...Ch. 25 - Prob. 7CONQCh. 25 - Prob. 8CONQCh. 25 - Ehler-Danlos syndrome is a rare disorder caused by...Ch. 25 - 10. Hurler syndrome is due to a mutation in a gene...Ch. 25 - Like Hurler syndrome, Fabry disease involves an...Ch. 25 - Achondroplasia is a rare form of dwarfism caused...Ch. 25 - Prob. 13CONQCh. 25 - 14. Marfan syndrome is due to a mutation in a...Ch. 25 - 15. Sandhoff disease is due to a mutation in a...Ch. 25 - Describe the two assumptions that underlie the...Ch. 25 - Prob. 17CONQCh. 25 - What is a prion? Explain how a prion relies on...Ch. 25 - 19. Some people have a genetic predisposition for...Ch. 25 - What is the difference between an oncogene and a...Ch. 25 - Prob. 21CONQCh. 25 - Prob. 22CONQCh. 25 - Prob. 23CONQCh. 25 - Prob. 24CONQCh. 25 - Prob. 25CONQCh. 25 - Prob. 26CONQCh. 25 - Prob. 27CONQCh. 25 - With regard to cancer cells, which of the...Ch. 25 - Prob. 29CONQCh. 25 - 1. Which of the following experimental...Ch. 25 - Prob. 2EQCh. 25 - 3. What is meant by the term genetic testing? How...Ch. 25 - Prob. 4EQCh. 25 - 5. Chapter 21 describes a method known as Western...Ch. 25 - 6. An experimental assay for the blood-clotting...Ch. 25 - 7. Discuss ways to distinguish whether a...Ch. 25 - 8. The codon change (Gly-12 to Val-12) in...Ch. 25 - Explain how DNA microarrays are used in molecular...Ch. 25 - Make a list of the benefits that may arise from...Ch. 25 - 2. Our government has finite funds to devote to...Ch. 25 - Prob. 3QSDC
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A female born with Angelman syndrome carries a deletion in theAS gene (i.e., the UBE3A gene). Which parent transmitted thedeletion to her?a. Her father c. Either her mother or fatherb. Her motherarrow_forwardA patient has mental deficiency, a short stature, and the mongolian type of the eyelid fold. The microscopical examination of the patient's karyotype revealed the presence of trisomy on the 21-st chromosome. What do we call the disease which is caused by this chromosomal abnormality? Select one: a. Down's syndrome. b. Klinefelter's syndrome. O c. Turner's syndrome. d. Edward's syndrome. e. Patau syndrome.arrow_forwardLocus heterogeneity means that a genetic disordera. has a heterogeneous phenotype.b. is caused by mutations in two or more different genes.c. involves a structural change in multiple chromosomes.d. is inherited from both parentsarrow_forward
- Which of the following situations does not describes a chromosomal mutation? Select one: a. A cytosine nucleotide is substituted for thymine nucleotide in a gene. b. A portion of Chromosome 4 is deleted during interphase of meiosis. c. The sister chromatids of Chromosome 18 do not separate during anaphase II. d. A section of Chromosome 17 is duplicated leading to problems in the peripheral nervous system.arrow_forwardWhich pathology leads to an increased risk of Alzheimer’s disease? Select one: a. Accumulation of the Amyloid β peptide b. Homozygosity for the e2 ApoE allele c. Sedentary lifestyle in young adulthood d. A mutation in the presenilin 4 gene e. Increase in blood cholesterolarrow_forwardFragile X is a disorder which causes mental impairment in affected individuals. The trait which is due to a mutation in the FMR1 gene on the X chromosome is inherited in a recessive manner. An unaffected son was born to an affected man and an unaffected woman. The woman’s mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotype of the son. c. Is it possible for the couple to have an affected daughter? affected son? Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly. d. If the couple has four children, what is the probability that they will have three normal daughters and one normal son?arrow_forward
- A medical research firm developed a new test for bipolar disorder that tries to identify if specific series of genome codes are missing in a person's DNA. What is the focus of the firm's test? Select one: a. chorionic villus samples Incorrect b. copy number variations c. diathesis-stress markers d. autosomal mutationsarrow_forwardHemophilia in humans is due to a mutation on the X chromosome. What will be the result of mating between a normal (non-carrier) female and a hemophiliac male? A. Half of the daughters are normal and half of the sons are hemophiliacs. B. All sons are normal and all daughters are carriers. C. All daughters are normal and all sons are carriers. D. Half of the children are normal and the other half are hemophiliacs; All daughters are carriers.arrow_forwardA young man went to the doctor because he had small testes and enlarged breasts. Through chromosomal testing, it was determined that this young man had the sex chromosomes XXY. Identify the syndrome with which this young man was MOST likely diagnosed. A. Turner syndrome B. Klinefelter syndrome C. Cri du Chat syndrome D. Down syndromearrow_forward
- In genetic maternal effect, the phenotype of the individual is determined by which of these statements? A. The sex of the parent who transmits the gene B. The nuclear genotype of the maternal parent C. The sex of the individual with only one sex able to express the phenotype D. Cytoplasmic genes usually located in the mitochondria E. A combination of environmental factors and the genotype of the individualarrow_forwardWhich pathology leads to an increased risk of Alzheimer’s disease? Select one: a. Homozygosity for the e3 ApoE allele b. a sedentary life style c. A mutation in the amyloid precursor protein gene d. a diet high in fat and sugars e. Homozygosity for the e4 ApoE allelearrow_forwardChromosome translocations include: A. Alterations in which the genetic material remains the same but rearranged B. Alterations in which the total amount of genetics information increases C. Alterations in which the total amount of genetics information decreases D. Variations in the chromosome numberarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY