Fragile X is a disorder which causes mental impairment in affected individuals. The trait which is due to a mutation in the FMR1 gene on the X chromosome is inherited in a recessive manner. An unaffected son was born to an affected man and an unaffected woman. The woman’s mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotype of the son. c. Is it possible for the couple to have an affected daughter? affected son? Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly. d. If the couple has four children
Fragile X is a disorder which causes mental impairment in affected individuals. The trait which is due to a mutation in the FMR1 gene on the X chromosome is inherited in a recessive manner. An unaffected son was born to an affected man and an unaffected woman. The woman’s mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotype of the son. c. Is it possible for the couple to have an affected daughter? affected son? Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly. d. If the couple has four children
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Fragile X is a disorder which causes mental impairment in affected individuals. The trait which is due to
a mutation in the FMR1 gene on the X chromosome is inherited in a recessive manner. An unaffected
son was born to an affected man and an unaffected woman. The woman’s mother was affected while
the father was normal.
a. Indicate the gene notation.
b. Give the genotype of the son.
c. Is it possible for the couple to have an affected daughter? affected son? Derive the genotypic and
d. If the couple has four children, what is the probability that they will have three normal daughters
and one normal son?
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