Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 25.2, Problem 2COMQ
Haplotype association studies are aimed at the identification of a particular ______based on ______.
a. chromosome, an abnormality in its structure
b. chromosome, the arrangement of molecular markers
c. gene, its linkage to other genes or molecular markers
d. gene, chromosomal rearrangements
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Students have asked these similar questions
1. _____________ frequencies are used to obtain a genetic map.A. TransductionB. ReconstitutionC. TransformationD. RecommendationE. Recombination
2. A __________ shows an individual cell's metaphase chromosomes arranged in pairs and sorted by size.A. phenotypeB. genotype C. karyotypeD. fingerprintE. none of the above
3. During conjugation, E.coli chromosomal transfer begins at ________.A. oriVB. oriCC. oriTD. oriAE. none of the above
Choose the phrase from the right column that best fitsthe term in the left column.a. DNA polymorphism 1. DNA element composed of shorttandemly repeated sequencesb. phase 2. two different nucleotides appearat the same position in genomicDNA from different individualsc. informative cross 3. arrangement of alleles of twolinked genes in a diploidd. ASO 4. location on a chromosomee. SNP 5. a DNA sequence that occurs intwo or more variant formsf. DNA fingerprinting 6. a short oligonucleotide that willhybridize to only one allele at achosen SNP locusg. SSR 7. detection of genotype at anumber of unlinked highlypolymorphic locih. locus 8. allows identification of a gamete asrecombinant or nonrecombinanti. compound 9. all exons in a genomeheterozygotej. exome 10. individual with two differentmutations in the same gene
Which of the following is correct regarding polytene chromosomes?
options:
A.
Exposure to a sublethal dose of X-rays causes spontaneous mutations.
B.
Polytene chromosomes have been useful to observe specific bands correlated with individual genes.
C. Both A and B
D. None of the above
Chapter 25 Solutions
Genetics: Analysis and Principles
Ch. 25.1 - Which of the following wouldnotbe consistent with...Ch. 25.1 - 2. Assuming complete penetrance, which type of...Ch. 25.1 - 3. Which of the following is not a common...Ch. 25.1 - Prob. 4COMQCh. 25.2 - Prob. 1COMQCh. 25.2 - Haplotype association studies are aimed at the...Ch. 25.3 - 1. Which of the following is not a method used in...Ch. 25.3 - 2. Which of the following prenatal genetic testing...Ch. 25.4 - Prob. 1COMQCh. 25.5 - 1. An oncogene is produced from a ________that has...
Ch. 25.5 - Which of the following is a type of genetic change...Ch. 25.5 - 3. Tumor-suppressor genes promote cancer...Ch. 25.5 - 4. Normal (nonmutant) tumor-suppressor genes often...Ch. 25.5 - Prob. 5COMQCh. 25.6 - Prob. 1COMQCh. 25 - 1. With regard to pedigree analysis, make a list...Ch. 25 - 2. Explain, at the molecular level, why human...Ch. 25 - 3. Many genetic disorders exhibit locus...Ch. 25 - Prob. 4CONQCh. 25 - Prob. 5CONQCh. 25 - Figure 25.1 illustrates albinism in two different...Ch. 25 - Prob. 7CONQCh. 25 - Prob. 8CONQCh. 25 - Ehler-Danlos syndrome is a rare disorder caused by...Ch. 25 - 10. Hurler syndrome is due to a mutation in a gene...Ch. 25 - Like Hurler syndrome, Fabry disease involves an...Ch. 25 - Achondroplasia is a rare form of dwarfism caused...Ch. 25 - Prob. 13CONQCh. 25 - 14. Marfan syndrome is due to a mutation in a...Ch. 25 - 15. Sandhoff disease is due to a mutation in a...Ch. 25 - Describe the two assumptions that underlie the...Ch. 25 - Prob. 17CONQCh. 25 - What is a prion? Explain how a prion relies on...Ch. 25 - 19. Some people have a genetic predisposition for...Ch. 25 - What is the difference between an oncogene and a...Ch. 25 - Prob. 21CONQCh. 25 - Prob. 22CONQCh. 25 - Prob. 23CONQCh. 25 - Prob. 24CONQCh. 25 - Prob. 25CONQCh. 25 - Prob. 26CONQCh. 25 - Prob. 27CONQCh. 25 - With regard to cancer cells, which of the...Ch. 25 - Prob. 29CONQCh. 25 - 1. Which of the following experimental...Ch. 25 - Prob. 2EQCh. 25 - 3. What is meant by the term genetic testing? How...Ch. 25 - Prob. 4EQCh. 25 - 5. Chapter 21 describes a method known as Western...Ch. 25 - 6. An experimental assay for the blood-clotting...Ch. 25 - 7. Discuss ways to distinguish whether a...Ch. 25 - 8. The codon change (Gly-12 to Val-12) in...Ch. 25 - Explain how DNA microarrays are used in molecular...Ch. 25 - Make a list of the benefits that may arise from...Ch. 25 - 2. Our government has finite funds to devote to...Ch. 25 - Prob. 3QSDC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- To map the distance between molecular markers via testcrosses,the markers must bea. polymorphic. c. fluorescently labeled.b. monomorphic. d. on different chromosomes.arrow_forward1. The figure below represents a karyotype performed on a somatic cell of an unknown organism. Answer the following questions using the figure. а. What is the ploidy of this organism? Provide evidence for your answer. b. How many chromosomes does this organism have? c. Circle (and label) 3 different sets of homologous chromosomes? d. Is there evidence for a chromosomal aberration? If so, describe the evidence. If not, explain your reasoning. CTM D CT IDarrow_forwardA geneticist determines that the order of four genes on a specific chromosome is CABD because the recombination frequencies were 35% for C-D, 24% for A-D, 23% for B-D, and 10% for A-B. What has the geneticist constructed? A. a physical map B. a karyotype C. a cytogenic map D. a linkage maparrow_forward
- When recombination (“crossing over”) doesn’t happen correctly, what type(s) of mutations that can occur? Mark all that apply Select one or more: a. Deletion of part of a chromosome b. Translocation (transfer of part of a chromosome to a non-homologous chromosome) c. Duplication of part of a chromosome d.Inversion (reversal or “flipping” of part of a chromosome)arrow_forward1.) Chromosome images are obtained from any cell type that has a nucleus. 2.) Chromosomes can be obtained from reticulocytes. a. Both are correct b. Both are incorrect c. Statement 1 is incorrect. Statement 2 is correct.arrow_forwardIn addition to DNA swapping, another contributor to the uniqueness of eggs/sperm and people is ____________ that happens in _______________. A. mutations in DNA; reproductive tissues at puberty B. DNA replication errors; Interphase C. random lining up of chromosomes across the middle of the cell; Metaphase D. decondensing of chromosomes; interkinesis and cytokinesisarrow_forward
- Which of the following was used to label protein in the hereditary material for genetic information study? a. ^32P b. ^35S c. ^35P d. ^32Sarrow_forward1. Choose the phrase from the right column that best fitsthe term in the left column.a. cytoplasmicsegregation1. transmission of genes through maternalgamete onlyb. heteroplasmic 2. cell that has mtDNAs or cpDNAs all of onegenotypec. homoplasmic 3. having gametes of similar sized. maternalinheritance4. a cell with a mixture of different mtDNAsgenerates a daughter cell with only one kinde. uniparentalinheritance5. a specific fraction of wild-type organellarDNAs is required for a wild-type phenotypef. isogamous 6. cell with mtDNAs or cpDNAs with differentgenotypesg. threshold effect 7. transmission of genes through either amaternal or a paternal gamete, but not botharrow_forward. Match each term to its corresponding definition. 1. the chromosomes that do not determine the sex of an individual 2. the sex chromosomes of a human female 3. the chromosomes that determine the sex of an individual 4. the sex chromosomes of a human male 5. a picture of the chromosomes of an individual a. XX b. autosomes c. karyotype d. XY e. sex chromosomesarrow_forward
- II Pause The diagram below is a pedigree showing the inheritance pattern of a disease in a family. II Legend affected female unaffected female affected male unaffected male What is the probability that one of the daughter's children will have the disease if she has children with a male who is an unaffected carrier of the gene? O A. 0% O B. 100% O C. 75% O D. 50%arrow_forwardPreimplantation genetic diagnosis would be least useful in detecting adisease-causing allele.a. dominantb. recessivec. commond. rarearrow_forwardUnder the influence of gamma-radiation a fragment of the chromosome was lost. What chromosomal mutation is it? Select one: a. Deletion. b. Duplication. c. Inversion. d. Intrachromosomal translocation. O e. Interchromosomal translocation.arrow_forward
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