Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 22, Problem 16P
In Fig. 22.14c, the fw2.2 causal gene was validated by introducing the S. pennellii version of the gene into S. lycopersicum. Why was the experiment done this way, rather than the other way around?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Which of the following best describes the control group for this experiment?
a) mating between male flies raised on maltose medium and female flies on starch medium.b) mating between male and female flies raised on starch medium in different populations.c)mating between female flies raised on maltose medium and male flies raised on starch medium.
In an imagined transduction experiment with alleles a+, b+,and c+, a+ alone was transduced into an auxotroph 800 times, b+ alone 1200 times, and c+ alone 1500 times. Genes a+ and b+ were both found 3 times, b+ and c+ 12 times, and a+ and c+ one time. What can you conclude regarding the linkage of the three alleles (which is two are closer together).
Help me please i will rate
A shuttle vector is a vector constructed so that it can propagate in two different host species.
One of the most common types of shuttle vectors is the yeast shuttle vector.
(1)
Name the THREE (3) most common yeast shuttle vectors.
(ii)
Based on the answer above, differentiate these THREE (3) vectors.
Chapter 22 Solutions
Genetics: From Genes to Genomes
Ch. 22 - Choose the best matching phrase in the right...Ch. 22 - Suppose you grew genetically identical dandelion...Ch. 22 - How can each of the following be used in...Ch. 22 - Two different groups of scientists studying a rare...Ch. 22 - Which of the following statements would be true of...Ch. 22 - Studies have indicated that for pairs of twins...Ch. 22 - Prob. 7PCh. 22 - Prob. 8PCh. 22 - Table 22.2 lists concordance values for MZ and DZ...Ch. 22 - Prob. 10P
Ch. 22 - Prob. 11PCh. 22 - Two alleles at one locus produce three distinct...Ch. 22 - In a certain plant, leaf size is determined by...Ch. 22 - Compare and contrast the use of SNP genotyping: i...Ch. 22 - Explain the similarities and differences between...Ch. 22 - In Fig. 22.14c, the fw2.2 causal gene was...Ch. 22 - Among the most prevalent pathologies that afflict...Ch. 22 - Human geneticists have found the Finnish...Ch. 22 - Canavan disease, caused by homozygosity for a...Ch. 22 - In GWAS analysis, because of the existence of LD...Ch. 22 - In Fig. 22.15: a. Why do some chromosomes in the...Ch. 22 - Consider the triangle diagram shown in Fig. 22.17....Ch. 22 - Prob. 23PCh. 22 - You conduct a Case/Control study comparing the...Ch. 22 - Prob. 25PCh. 22 - ALS amyotrophic lateral sclerosis is a rare, fatal...Ch. 22 - Through GWAS explorations, scientists have...Ch. 22 - In domesticated dogs, size has a high...Ch. 22 - Suppose a GWAS investigation found a particular LD...Ch. 22 - In 2008, Time magazine named as its invention of...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- When the S.cerevisiae genome was sequenced and surveyed for possible genes, only about 40% of those genes had been previously identified in forward genetic screens. This left about 60% of predcited genes with no known function, leading some to dub the genes fun (function unknown) genes. a)As an approach to understanding the function of a certain fun gene, you wish to create a loss of function allele. How would you do this? b)You wish to know the physical location of the encoded protein product. How would you obtain such information?arrow_forwardDNA from a strain of Bacillus subtilis with genotype a+ b+ c+ d+ e+ is used to transform a strain with genotype a− b− c− d− e−. Pairs of genes are checked for cotransformation, and the following results are obtained: Pair of genes Cotransformation Pair of genes Cotransformation a+ and b+ No b+ and d+ No a+ and c+ No b+ and e+ Yes a+ and d+ Yes c+ and d+ No a+ and e+ Yes c+ and e+ Yes b+ and c+ Yes d+ and e+ No On the basis of these results, what is the order of the genes on the bacterial chromosome?arrow_forwardDNA from a strain of Bacillus subtilis with the genotype trp+ tyr+ was used to transform a recipient strain with the genotype trp− tyr−. The following numbers of transformed cells were recovered: Genotype Number of transformed cells trp+ tyr− 154 trp− tyr+ 312 trp+ tyr+ 354 What do these results suggest about the linkage of the trp and tyr genes?arrow_forward
- DNA from a strain of Bacillus subtilis with genotype a* b* c* d* e* is used to transform a strain with genotype a b c d e. Pairs of genes are checked for cotransformation, and the following results are obtained: Pair of genes Cotransformation Pair of genes Cotransformatic a* and b* No b* and d* No a* and c* No b* and e* Yes a* and d* Yes c* and d* No a* and e* Yes c* and e* Yes b* and c* Yes d* and e* No On the basis of these results, what is the order of the genes on the bacterial chromosome?arrow_forwardIn five Hfr strains, each of which was used to build a time-of-transfer map, the genes entered the recipient cells as follows: Strain 1: S L A C T F Strain 2: N P F T C A Strain 3: T F P N U Y Strain 4: S H Y U N P Strain 5: U N P F T C Which of the following represents a correct gene map of these results? N P F T S L A C H U Y S L A C T F P N H Y U C T F P N U Y H S L A T C A L S P N U Y H F U N P C A L S F T H Yarrow_forwardAustin Taylor and Edward Adelberg isolated some new strains of Hfr cells that they then used to map several genes in E. coli by using interrupted conjugation . In one experiment, they mixed cells of Hfr strain AB-312, which were xyl+ mtl+ mal+ met+ and sensitive to phage T6, with F− strain AB-531, which was xyl− mtl− mal− met− and resistant to phage T6. The cells were allowed to undergo conjugation. At regular intervals, the researchers removed a sample of cells and interrupted conjugation by killing the Hfr cells with phage T6. The F− cells, which were resistant to phage T6, survivedand were then tested for the presence of genes transferred from the Hfr strain. The results of this experiment are shown in the accompanying graph. On the basis of these data, give the order of the xyl, mtl, mal, and met genes on the bacterial chromosome and indicate the minimum distances between them.arrow_forward
- Comparison of the genomes of wild-type bovine tuberculosis strains of Mycobacterium bovis and contemporary M. bovis-derived Bacille Calmette-Guerin (BCG) vaccine strains with that of a virulent reference strain of M. tuberculosis indicated that almost 100 M. tuberculosis genes were found to be “missing” from all of the M. bovis and BCG isolates that were used for making making the vaccines. Describe how you might isolate and identify those genes that are unique to M. tuberculosis.arrow_forwardWhat are the two main phenomena responsible for the emergence of new strains of influenza A? Briefly describe how these events develop and contribute to emergence of new strains.arrow_forwardUsing the technique of interrupted mating, five Hfr strains were tested for the sequence in which they transmitted several different genes to an F- strain. Each Hfr strain was found to transmit its genes in a unique sequence, as follows (only the first six genes transmitted were scored). Hfr 1 F O P R S Q Hfr 2 R P O F G Y Hfr 3 Y X W Q S R Hfr 4 W Q S R P O Hfr 5 F G Y X W Q A. For each of the Hfr strains, state which donor-gene marker should be selected in the recipients after conjugation to obtain the highest proportion of recombinants that will be Hfr? Strain 1 Strain 2 Strain 3 Strain 4 Strain 5arrow_forward
- The map below was constructed using information from an interrupted mating experiment. Str# refers to the strain numnber from which the data were obtained. The strains that are referenced by the Str#'s on the map are considered to be F+ strains. The units for the map distance values on this map are minutes Assume that four genes were transferred by each strain in the interrupted mating experiment. Based on this map, list in order of transfer (first to last) the genes transferred by Str4. Type your answer by typing in the letters that represent the genes without any spaces so that Moodle can grade it correctly. K Str2 10 9 Strl W B Str5 8. H. R Str3 Str6. 11 A Str4 12arrow_forwardPenicillin was first used in the 1940s to treat gonorrhea infections produced by the bacterium Neisseria gonorrhoeae. In 1984, according to the CDC, fewer than 1% of gonorrhea infections were caused by penicillin-resistant N. gonorrhoeae. By 1990, more than 10% of cases were penicillin resistant and a few years later the level of resistance was 95%. Explain the various ways this resistance could be spread among the cells. Could this resistance pass to other infectious bacteria from N. gonorrhoeae?arrow_forwardA research group is studying a bacterium X that binds to mucosal cells in the lung and invades. Wildtype X has an LD50 value of 10 bacteria when administered to mice by inhalation. Using transposon mutagenesis, the researchers have isolated two mutants of X that they call Xmut1 and Xmut2, both of which have LD50 values of 105 when inhaled by mice. However, in tissue culture cells, Xmut1 can invade the cells just as well as wild-type X, while Xmut2 cannot. Provide a possible explanation for these results.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Mechanisms of Genetic Change or Evolution; Author: Scientist Cindy;https://www.youtube.com/watch?v=5FE8WvGzS4Q;License: Standard Youtube License