Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 22, Problem 12P

Two alleles at one locus produce three distinct phenotypes. Two alleles of two genes lead to five distinct phenotypes. Two alleles of six genes lead to 13 distinct phenotypes. (These statements assume that the alleles at any one locus are codominant or incompletely dominant and that each gene makes an equal contribution to the phenotype.)

a. Derive a formula to express this relationship. (Let n equal the number of genes.)
b. Each of the most extreme phenotypes for a trait determined by two alleles at one locus are found in a proportion of 1/4 in the F2 generation. If two alleles of two genes determine the trait, each extreme phenotype will be present in the F2 as 1/16 of the population.
In common wheat (Triticum aestivum), kernel color varies from red to white and the genes controlling the color act additively, that is, alleles for each gene are incompletely dominant and each gene contributes equally to the color. A true-breeding red variety is crossed to a true-breeding white variety, and 1/256 of the F2 have red kernels and 1/256 have white kernels. How many genes control kernel color in this cross?
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Two alleles at one locus produce three distinctphenotypes. Two alleles of two genes lead tofive distinct phenotypes. Two alleles of six geneslead to 13 distinct phenotypes. (These statementsassume that the alleles at any one locus arecodominant or incompletely dominant andthat each gene makes an equal contributionto the phenotype.)a. Derive a formula to express this relationship. (Letn equal the number of genes.)b. Each of the most extreme phenotypes for a traitdetermined by two alleles at one locus are foundin a proportion of 1/4 in the F2 generation. If twoalleles of two genes determine the trait, each extreme phenotype will be present in the F2 as 1/16of the population.In common wheat (Triticum aestivum),kernel color varies from red to white andthe genes controlling the color act additively,that is, alleles for each gene are incompletelydominant and each gene contributes equallyto the color. A true-breeding red variety iscrossed to a true-breeding white variety, and1/256 of the F2…
Normal pigmentation in humans is completely dominant to albinism. A couple who are both carriers for albinism decided to have children.  a. Given that their first offspring normally pigmented, what is the probability that the child is a carrier? b. Considering the same genotypes of parents, what is the likelihood that three albino and two are normally pigments in a brood of five?
A recessive maternal effect mutant in zebrafish, called ichabod, results in embryos lacking heads that  are non-viable. You have been instructed to identify females that are homozygous for the ichabod mutant allele. At your disposal are a tank of wild-type fish (males and females), a tank of male and female parental fish that are all heterozygous for the ichabod mutant allele (ichabod/+), and a tank of F1 fish derived from a cross between a heterozygous male and heterozygous female (ichabod/+). Which of the following would be a way to identify females that are homozygous mutant, i.e. ichabod/ichabod? Select all answers that would work.

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Genetics: From Genes to Genomes

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