Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 19, Problem 27P

Answer the following in regard to multifactorial traits in human twins.

a. If the trait is substantially influenced by genes, would you expect the concordance rate to be higher in MZ twins or higher in DZ twins? Explain your reasoning.

b. If the trait is produced with little contribution from genetic variation, what would you expect to see if you compared the concordance rates of MZ twins versus DZ twins? Explain your reasoning.

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Suppose that a geneticist studies a series of characteristics in monozygotic twins and dizygotic twins. He finds various rates of phenotypic concordance for the characteristics, as shown in the table. Rate of phenotypic concordance (%) Characteristic Monozygotic Dizygotic migraine headache 60 30 eye color 100 40 measles 90 90 clubfoot 30 10 high blood pressure 70 40 handedness 70 70 tuberculosis Classify each characteristic according to whether the corresponding rates of concordance indicate a genetic influence, an environmental influence, or both genetic and environmental influences.
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Genetic Analysis: An Integrated Approach (3rd Edition)

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