Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 19, Problem 25P
In human gestational development, abnormalities of the closure of the lower part of the midface can result in cleft lip, if the lip alone is affected by the closure defect, or in cleft lip and palate (the roof of the mouth), if the closure defect is more extensive. Cleft lip and cleft lip with cleft palate are multifactorial disorders that are threshold traits. A family with a history of either condition has a significantly increased chance of a recurrence of midface cleft disorder in comparison with families without such a history. However, the recurrence risk of a midface cleft disorder is higher in families with a history of cleft lip with cleft palate than in families with a history of cleft lip alone.
a. Suppose a friend of yours who has not taken genetics asks you to explain these observations. Construct a genetic explanation for the increased recurrence risk of midface clefting in families that have a history of cleft disorders versus families without a history of such disorders.
b. Construct a similar explanation of why the recurrence risk of a cleft disorder is higher in families with a history of cleft lip with cleft palate than in families with a history of cleft lip alone.
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Almond-shaped (E) eyes is dominant over round eyes. Presence of freckles (F) is also a dominant trait. Medium-sized nose, however, may be inherited if one parent has a large (L) nose and the other has a small (S) nose. Achondroplasia (A) is an autosomal dominant disorder that leads to dwarfism but not lethal.A woman homozygous for normal height, with freckles, almond-shaped eyes, small nose, and Type A blood, has a Type O mother with no freckles and a type AB father with round eyes. She is engaged to a man with achondroplasia, round eyes and medium sized nose. Unlike his father, his mother is of normal height. Both his parents have Type O blood but nobody from both sides of his family has or had freckles.
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Indicate the nature of the trait and type of inheritance involved in each of the following situations. (a) Children who exhibit this trait have at least one parent who exhibits the same trait. (b) Children exhibit this trait even though neither parent does.
Indicate the nature of the trait and type of inheritance involved in each of the following situations. (a) Children who exhibit this trait have at least one parent who exhibits the same trait. (b) Children exhibit this trait even though neither parent does. (c) The trait is expressed more commonly in sons than indaughters. (d) Tongue-rolling is expressed equally in both daughters and sons.
Chapter 19 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 19 - Which of the following traits would you expect to...Ch. 19 - 19.2 For the traits listed in the previous...Ch. 19 - Compare and contrast broad sense heritability and...Ch. 19 - 19.4 In a cross of two pure-breeding lines of...Ch. 19 - 19.5 Describe the difference between continuous...Ch. 19 - Prob. 6PCh. 19 - 19.7 Provide a definition and an example for each...Ch. 19 - 19.8 What is a random sample, and why can a random...Ch. 19 - 19.9 Why is heritability an important phenomenon...Ch. 19 - 19.10 Three pairs of genes with two alleles each (...
Ch. 19 - 19.11 In selective breeding experiments, it is...Ch. 19 - 19.12 Two inbred lines of sunflowers produce...Ch. 19 - What is quantitative trait locus (QTL)? Suppose...Ch. 19 - 19.14 In Nicotiana, two inbred strains produce...Ch. 19 - 19.15 Suppose the length of maize ears has narrow...Ch. 19 - In a line of cherry tomatoes, the average fruit...Ch. 19 - 19.17 Two purebreeding wheat strains, one...Ch. 19 - Prob. 18PCh. 19 - During a visit with your grandparents, they...Ch. 19 - 19.20 An association of racehorse owners is...Ch. 19 - Prob. 21PCh. 19 - Suppose a polygenic system for producing color in...Ch. 19 - New Zealand lamb breeders measure the following...Ch. 19 - Cattle breeders would like to improve the protein...Ch. 19 - In human gestational development, abnormalities of...Ch. 19 - The children of couples in which one partner has...Ch. 19 - Answer the following in regard to multifactorial...Ch. 19 - 19.28 Suppose the mature height of a plant is a...Ch. 19 - A three-gene system of additive genes (A, B, and...Ch. 19 - 19.30 Congenital dislocation of the hip is a...Ch. 19 - A total of 20 men and 20 women volunteer to...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
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- Suppose a couple brought to you their 8-year old boy with progressive muscle weakness, and difficulty in motor skills resulting to awkward manner of walking and running . The boy’s 15-year old sister and 11-year old brother appear to be unaffected. They have a normal father and a normal pregnant mother. The mother had a brother who died at 26 yrs. of age with similar findings that seemed to worsen with age. The mother also has a sister with the same findings but it only manifested during her 28th Her sister, who married an unaffected man, has two affected sons and a normal daughter. You suspect a diagnosis of Duchenne Muscular Dystrophy (DMD). Draw the pedigree of this family. Follow protocols in making a pedigree. Provide the genotype of all individuals in the pedigree. Please provide also the gene notation. What is the risk (probability) that the fetus is affected? Amniocentesis has to be performed in order to determine the sex of the fetus. What is the risk that the child will be…arrow_forwardPlease explain whether parents who have medium skin color (AaBbCc) can have children with the darkest skin color. If this is possible, please explain or show this and provide the likelihood that they would have a child that is (AABBCC).arrow_forwardDefine incomplete dominance. Describe autosomal dominant and autosomal recessive disorder with ONE example.arrow_forward
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