Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 19, Problem 26P
The children of couples in which one partner has blood type O (genotype
a. What is the expected concordance rate for blood type of MZ twins in this study? Explain your answer.
b. What is the expected concordance rate for blood type of DZ twins in this study? Explain why this answer is different from the answer to part (a).
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Cystic fibrosis is an autosomal recessive disease characterized by two copies of a mutated CFTR gene. If one in 100 (hypothetical scenario, not reality) people in the United States have cystic fibrosis, calculate the p and q frequency for the normal allele (p) and the mutated allele (q). Based on those calculations, what percentage of individuals would be expected to be homozygous dominant?
Two parents, both with blood type A, have three children in a row with blood type O.
a. Is this possible? If not, why not? If so, give the genotypes of the parents.
i. What are the odds that, given the genotypes you list in 2.e., that the described scenario would actually happen?
b. Could other children of this pair be born with blood type AB? Why not?
Suppose there is an autosomal locus of 2 alleles, A1 and A2, with probabilities (frequencies) p1 and p2, and the genotype probabilities (frequencies) are P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2, respectively. Prove the Hardy-Weinberg Law, i.e., after one generation of random mating, the genotype probabilities (frequencies) in the offspring are also P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2. Hint: List all possible combinations of random mating. Then list the probabilities of the resulting genotype probabilities (frequencies) in the offspring. Combine the probabilities of random mating and resulting genotype probabilities (frequencies) in the offspring.
Chapter 19 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 19 - Which of the following traits would you expect to...Ch. 19 - 19.2 For the traits listed in the previous...Ch. 19 - Compare and contrast broad sense heritability and...Ch. 19 - 19.4 In a cross of two pure-breeding lines of...Ch. 19 - 19.5 Describe the difference between continuous...Ch. 19 - Prob. 6PCh. 19 - 19.7 Provide a definition and an example for each...Ch. 19 - 19.8 What is a random sample, and why can a random...Ch. 19 - 19.9 Why is heritability an important phenomenon...Ch. 19 - 19.10 Three pairs of genes with two alleles each (...
Ch. 19 - 19.11 In selective breeding experiments, it is...Ch. 19 - 19.12 Two inbred lines of sunflowers produce...Ch. 19 - What is quantitative trait locus (QTL)? Suppose...Ch. 19 - 19.14 In Nicotiana, two inbred strains produce...Ch. 19 - 19.15 Suppose the length of maize ears has narrow...Ch. 19 - In a line of cherry tomatoes, the average fruit...Ch. 19 - 19.17 Two purebreeding wheat strains, one...Ch. 19 - Prob. 18PCh. 19 - During a visit with your grandparents, they...Ch. 19 - 19.20 An association of racehorse owners is...Ch. 19 - Prob. 21PCh. 19 - Suppose a polygenic system for producing color in...Ch. 19 - New Zealand lamb breeders measure the following...Ch. 19 - Cattle breeders would like to improve the protein...Ch. 19 - In human gestational development, abnormalities of...Ch. 19 - The children of couples in which one partner has...Ch. 19 - Answer the following in regard to multifactorial...Ch. 19 - 19.28 Suppose the mature height of a plant is a...Ch. 19 - A three-gene system of additive genes (A, B, and...Ch. 19 - 19.30 Congenital dislocation of the hip is a...Ch. 19 - A total of 20 men and 20 women volunteer to...
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