Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 18, Problem 14QP

A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twin’s risk decrease if he were raised in an environment different from that of his schizophrenic brother?

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A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twin’s risk decrease if he were raised in an environment different from that of his schizophrenic brother?
What are newest advances in early diagnosis and confirmation of Huntington disease? Explain the difference in inheritance pattern and the frequency to have affected progeny in the case of these three inherited diseases: Huntington, Cystic fibrosis and Duchenne muscular dystrophy. What therapies can be used or recommended for patients experiencing any of these inherited diseases?
Niemann Pick Type C disease is a recessive disorder that causes the accumulation of cholesterol and other lipids in lysosomes, ultimately affecting both the liver and the nervous system.  Below are the genotypes and phenotypes of offspring of a family with a history of Niemann Pick.  7 NN ( all normal phenotype) 3 Nn  (all normal phenotype) 4  nn (1 early onset dementia, 1 mid-life onset dementia, 2 late-onset dementia).    From this information, Niemann-Pick disease is an example of: A) variable expressivity B) incomplete dominance C) incomplete penetrance D) variable expressivity and incomplete penetrance   E) multiple alleles
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