Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Textbook Question
Chapter 17, Problem 20RA
Describe the transport properties of the nephron loop and explain the interactions between the ascending and descending limbs in the countercurrent multiplier system. What is the functional significance of this system?
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Describe the special characteristics of the descending and ascending limbs of the nephron loop that cause the formation of the medullary osmotic gradient.
Explain why the filtrate becomes hypotonic as it flows through the ascending limb of the nephron loop. Also explain why the filtrate at the bend of the nephron loop (and the interstitial fluid of the deep portions of the medulla) is hypertonic.
Describe two mechanisms in the PCT, one in the nephron loop, one in the DCT, and one in the collecting duct for reabsorption of Na . What other solutes are reabsorbed or secreted with Na in each mechanism?
Chapter 17 Solutions
Human Physiology
Ch. 17 - Describe the "theme" of kidney function in a...Ch. 17 - Draw and label the tubular components of a nephron...Ch. 17 - Trace the course of tubular fluid from the...Ch. 17 - Trace the course of blood flow through the kidney...Ch. 17 - Describe the structures that plasma fluid must...Ch. 17 - Describe the forces that affect the formation of...Ch. 17 - Explain the significance of the glomerular...Ch. 17 - Prob. 5bCPCh. 17 - Describe the mechanisms for salt and water...Ch. 17 - Compare the transport of and water across the...
Ch. 17 - Describe the interaction between the ascending and...Ch. 17 - Explain how ADH helps the body conserve water. How...Ch. 17 - Define renal plasma clearance and describe how...Ch. 17 - Define the terms reabsorption and secretion. Using...Ch. 17 - Explain why the total renal blood flow can be...Ch. 17 - Define transport maximum and renal plasma...Ch. 17 - Describe the effects of aldosterone on the renal...Ch. 17 - Prob. 11bCPCh. 17 - Explain the mechanisms by which the cortical...Ch. 17 - Explain how the kidneys reabsorb filtered...Ch. 17 - Suppose a person with diabetes mellitus had an...Ch. 17 - List the different categories of clinical...Ch. 17 - Explain why most diuretics can cause excessive...Ch. 17 - Define uremia and discuss the dangers associated...Ch. 17 - Which of these statements about the renal pyramids...Ch. 17 - Match the following items:
Active transport of...Ch. 17 - Match the following items:
Active transport of...Ch. 17 - Match the following items:
Passively permeable to...Ch. 17 - Match the following items:
Passively permeable to...Ch. 17 - Antidiuretic hormone promotes the retention of...Ch. 17 - Aldosterone stimulates sodium reabsorption and...Ch. 17 - Substance X has a clearance greater than zero but...Ch. 17 - Prob. 9RACh. 17 - About of the glomerular ultrafiltrate is...Ch. 17 - Diuretic drugs that act in the nephron loop...Ch. 17 - The appearance of glucose in the urine a. occurs...Ch. 17 - Reabsorption of water through the tubules occurs...Ch. 17 - Which of these factors oppose(s) filtration from...Ch. 17 - The countercurrent exchange in the vasa recta...Ch. 17 - The kidneys help to maintain acid-base balance...Ch. 17 - Scientists currently believe that the main barrier...Ch. 17 - A drug that blocks the action of the organic anion...Ch. 17 - Explain how glomerular ultra filtrate is produced...Ch. 17 - Describe the transport properties of the nephron...Ch. 17 - Prob. 21RACh. 17 - Prob. 22RACh. 17 - Prob. 23RACh. 17 - Prob. 24RACh. 17 - Identify where secretion occurs in the nephron,...Ch. 17 - Which diuretic drugs do not produce hypokalemia?...Ch. 17 - Prob. 27RACh. 17 - Prob. 28RACh. 17 - Prob. 29RACh. 17 - Prob. 30RACh. 17 - Prob. 31RACh. 17 - Prob. 32RACh. 17 - s Suppose a woman with a family history of...Ch. 17 - Prob. 34RACh. 17 - Prob. 35RACh. 17 - Prob. 36RACh. 17 - Prob. 37RACh. 17 - Prob. 38RACh. 17 - Prob. 39RACh. 17 - Prob. 40RACh. 17 - Prob. 41RACh. 17 - Prob. 42RA
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- Describe (and label on a diagram) the structures of a nephron (including associated blood vessels) and give the functions of each structure.arrow_forwardAs the text noted, two-thirds of the water and solutes that the body reclaims by reabsorption in nephrons occurs in the proximal tubule. Proximal tubule cells have large numbers of mitochondria and demand a great deal of oxygen. Explain why.arrow_forwardDescribe the countercurrent multiplier mechanism in terms of the permeabilities of the different parts of the nephron and collecting system structures, and indicate the end result of functioning of the countercurrent multiplier. Describe the countercurrent exchanger mechanism.arrow_forward
- Explain why the filtrate becomes hypotonic as it flows through the ascending limb of the nephron loop and why the filtrate at the end of the nephron loop is hypertonic.arrow_forwardAlthough the kidneys are probably best known as filtration organs, tubular reabsorption (the second step of urine formation in a nephron) actually reclaims molecules that have already been filtered from the blood. Describe the tubular reabsorption process, including the structures and molecules involved, and explain why these molecules need to be reabsorbed. please helparrow_forwardWhat is the difference between filtration and reabsorption? Explain how hydrostatic, osmotic (or colloid oncotic), and osmosis influence fluid transport across the nephron.arrow_forward
- What are the unique features of Henle loops that contribute to countercurrent multiplication during urine production? Provide an explanation of how countercurrent multiplication is facilitated in nephrons, including all the factors that contribute to it.arrow_forwardDrugs that increase urine flow (diuretic drugs) are often employed in the treatment of hypertension (high blood pressure) or other disease states. Three physiological categories of such drugs are ones that (i) function as loop diuretics, (ii) inhibit the action of aldosterone, and (iii) block Na+ channels in the collecting ducts. Explain why each of these categories would be expected to increase Na+ excretion and urine flow.arrow_forwardNa+ ions are actively transported out of the tubules to help set up the countercurrent multiplier. Which of the following are sites of active Na+ ion transport in the nephron?arrow_forward
- Explain the concept of a countercurrent multiplier system and how it works in the kidneys. What is the importance of this system to the function of the kidneys?arrow_forwardThe highest concentration of salt occurs in the interstitial fluid at the bottom of the loop of Henle. Explain why the low-to-high salt gradient allows for maximal water retention as the filtrate moves through the nephron:arrow_forwardHow Did The Addition Of Aldosterone Affect Urine Volume(compared with baseline)? Can the reabsorption of solutes influence of water reabsorption in the nephron? Briefly explain.arrow_forward
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