Concept explainers
To determine: The ways the clinicians can respect the brother’s desire not to know whether he is suffering from DKC or not and can not be a suitable donor for her sister.
Introduction: Dyskeratosiscongenita (DKC) is is a rare human genetic disorder that occurs due to the mutation in the telomerase gene. DKC disease may lead to bone marrow failure resulting in reducingthe production of blood cells and anemia.
To determine: The reason that clinicians tell the sister about her brother condition of DKC.
Introduction: A 27-year-old woman is diagnosed with a dominant form of DKC and needs a bone marrow transplant to treat the disorder. A 13-year-old brother was identified as the best immunologically matched donor for her sister
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Concepts of Genetics (12th Edition)
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