Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
expand_more
expand_more
format_list_bulleted
Question
Chapter 11, Problem 26RA
Summary Introduction
To review:
The effect of antibodies produced against insulin-receptor proteins on the
Introduction:
The hormone, insulin, is produced by the beta cells of islets of Langerhans or pancreatic islets. In a situation where the blood-glucose level is high, insulin is released from the pancreatic cells which allows the liver, the skeletal muscle, and the adipose tissue to take up glucose from the bloodstream. The insulin binds to the receptors in the plasma membrane and recruits GLUT4 (glucose transporter type 4) carrier protein through signaling molecules.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Someone is born without the ability to create insulin. Describe and explain the effect this would have on their ability to maintain homeostasis of blood glucose.
Glycogen depletion resulting from intense, extensive exercise can lead to exhaustion and the inability to continue exercising. Some people also experience dizziness, an inability to concentrate, and a loss of muscle control. Account for these symptoms.
Islet cells in the pancreas are actively synthesizing and secreting insulin into the bloodstream. A scientist purifies different membranous fractions of these islet cells. In which fraction would she find insulin or its intermediates?
Chapter 11 Solutions
Human Physiology
Ch. 11 - Compare the four chemical classes of hormones with...Ch. 11 - Define prohormone and prehormone, and give...Ch. 11 - Prob. 1cCPCh. 11 - Prob. 2aCPCh. 11 - Prob. 2bCPCh. 11 - Prob. 3CPCh. 11 - Prob. 4aCPCh. 11 - Describe the sequence of events by which a hormone...Ch. 11 - Prob. 4cCPCh. 11 - Prob. 5aCP
Ch. 11 - Prob. 5bCPCh. 11 - List the hormones secreted by the anterior...Ch. 11 - Prob. 7CPCh. 11 - Prob. 8aCPCh. 11 - Prob. 8bCPCh. 11 - Prob. 9aCPCh. 11 - Prob. 9bCPCh. 11 - Describe the structure of the thyroid gland and...Ch. 11 - Describe how thyroid hormones are produced and how...Ch. 11 - Prob. 10cCPCh. 11 - Describe the location of the parathyroid glands...Ch. 11 - Prob. 12aCPCh. 11 - Describe how insulin and glucagon secretion are...Ch. 11 - Prob. 13CPCh. 11 - Prob. 14CPCh. 11 - Explain the nature of autocrine regulation. How...Ch. 11 - List some of the paracrine regulators produced by...Ch. 11 - Prob. 16aCPCh. 11 - Prob. 16bCPCh. 11 - Prob. 1RACh. 11 - Prob. 2RACh. 11 - Which of these statements about the adrenal cortex...Ch. 11 - Which of these statements about the hormone...Ch. 11 - Prob. 5RACh. 11 - Prob. 6RACh. 11 - Prob. 7RACh. 11 - Prob. 8RACh. 11 - Steroid hormones arc secreted by...Ch. 11 - Prob. 10RACh. 11 - Prob. 11RACh. 11 - Prob. 12RACh. 11 - Prob. 13RACh. 11 - Which of these hormones may have a primary role in...Ch. 11 - Prob. 15RACh. 11 - What do insulin-like growth factors,...Ch. 11 - Prob. 17RACh. 11 - Prob. 18RACh. 11 - Prob. 19RACh. 11 - Describe the sequence of events by which a hormone...Ch. 11 - Prob. 21RACh. 11 - Prob. 22RACh. 11 - Prob. 23RACh. 11 - Prob. 24RACh. 11 - Describe how thyroid hormone secretion is...Ch. 11 - Prob. 26RACh. 11 - Prob. 27RACh. 11 - Prob. 28RACh. 11 - Prob. 29RACh. 11 - Prob. 30RACh. 11 - Prob. 31RACh. 11 - Prob. 32RACh. 11 - Prob. 33RACh. 11 - Distinguish between the genomic and nongenomic...Ch. 11 - Prob. 35RACh. 11 - Diabetics who require insulin injections can...Ch. 11 - Prob. 37RACh. 11 - Prob. 38RACh. 11 - Prob. 39RACh. 11 - Prob. 40RA
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In type II diabetes, insulin is produced but is nonfunctional. These individuals are described as “starving in the sea of plenty” because their blood glucose levels are high, but none of the glucose is transported into the cells. Describe how this leads to malnutrition.arrow_forwardLipodystrophy is a condition in which an individual lacks adipose tissue. The muscles and liver from such individuals are insulin resistant, and both tissues accumulate large amounts of triacylglycer ols (hyperlipidemia). The administration of leptin partly ameliorates this condition. What does it indicate about the relation of adipose tissue to insulin action?arrow_forwardBodybuilders have been known to inject insulin to increase muscle mass because it stimulates protein anabolism. What is one of the risks associated with this practice in terms of K+ levels: elevated blood plasma K+ (hyperkalemia) or decreased blood plasma K+ (hypokalemia)? Could the practice of injecting insulin to increase muscle mass be fatal?arrow_forward
- Ob/ob knock-out (leptin deficient) mice put on abnormally high weight. These mice also cannot maintain body temperature. Explain why.arrow_forwardMarianne has type 1 diabetes. One day, after accidentally injecting herself with too much insulin, she starts to shake and feels confused. Following her doctor’s suggestion, she drinks a glass of orange juice—a ready source of glucose—and soon her symptoms subside. What caused her symptoms? How would a glucose-rich snack help?arrow_forwardLeptin inhibits eating and is secreted in amounts in direct proportion to body fat. Moreover, obese people have normal amounts of leptin and leptin receptor. Why, then, do people become obese?arrow_forward
- What aspect of β cell function ultimately fails as a result of overnutrition, causing the transition from insulin resistance to full-fledged type 2 diabetes?arrow_forwardMany diabetics do not respond to insulin because of a deficiency of insulin receptors on their cells. How does this aff ect (a) the levels of circulating glucose immediately after a meal and (b) the rate of glycogen synthesis in muscle?arrow_forwardWhich of the following statements about insulin istrue?a. Insulin acts as a transport protein, carryingglucose across the cell membrane.b. Insulin facilitates the movement of intracellularglucose transporters to the cell membrane.c. Insulin stimulates the breakdown of storedglycogen into glucose.d. Insulin stimulates the kidneys to reabsorbglucose into the bloodstreamarrow_forward
- describe a ketogenic diet. what are the pros and cons of such a diet. how is ketosis related to diabetes mellitus?arrow_forwardAs a result of complete fasting for 3 days, a significant change in metabolism occurs. How will the level of fatty acids in the blood change? What hormone causes these changes? Justify your answer schematically.arrow_forwardWhy glucose is given to patient who have low blood sugar level?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:Cengage
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
What is Metabolism?; Author: Stated Clearly;https://www.youtube.com/watch?v=nRq6N5NGD1U;License: Standard youtube license