Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 9, Problem 33P

Diagram a eukaryotic gene containing three exons and two introns, the pre-mRNA and mature mRNA transcript of the gene, and a partial polypeptide that contains the following sequences and features. Carefully align the nucleic acids, and locate each sequence or feature on the appropriate molecule.

the AG and GU dinucleotides corresponding to intron-exon junctions

the +1 nucleotide

the 5' UTR and the 3' UTR

the start codon sequence

a stop codon sequence

a codon sequence for the amino acids Gly-His-Arg at the end of exon 1 and a codon sequence for the amino acids Leu-Trp-Ala at the beginning of exon 2 .

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Consider the following DNA sequence, which codes for a short polypeptide: 5'-ATGGGCTTAGCGTAGGTTAGT-3' Determine the mRNA transcript of this sequence. You have to write these sequences from the 5' end to the 3' end and indicate those ends as shown in the original sequence in order to get the full mark. How many amino acids will make up this polypeptide?  Determine the first four anticodons that will be used in order to translate this sequence.
For each of the following items, fill in either the DNA strand, the MRNA codons, the tRNA anticodons, or the amino acid sequence that have been left blank. If several sequences might work, choose only one. Furthermore, circle the start and the stop codons of each mRNA sequence. 1. DNA (3'-5') ACG TAC GGC CGG TTA AAG CAT ACT TTC TTG MRNA TRNA Amino Acid 2. DNA (3'-5') MRNA AUG ACU AGC UGG GGG UAU UAC UUU UAG AAA TRNA Amino Acid 3. DNA (3'-5') MRNA TRNA GCU CCU UAC CAC ССС CGU AUG GCU GGG AUC Activate Go to Sett Amino Acid
Indicate which of the following items are associated with transcription or translation.  This could be in prokaryotes or eukaryotes, or both. Group of answer choices: Translation OR Transcription    Sigma binds to the promoter                                                    mRNA binds to the small ribosomal subunit                                                    Spliceosomes remove introns and splice together exons                                                    Nucleotides are added from the 5' to 3' end                                                    tRNA anticodon binds to the corresponding mRNA codon                                                    STOP codon results in termination

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Genetic Analysis: An Integrated Approach (3rd Edition)

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