(a)
To determine: The concentration gradient of protons across the epithelial membrane.
Introduction: The transport of sodium and potassium ions across the membrane is an active transport process, which involves the hydrolysis of adenosine triphosphate (ATP) to provide energy. The gastric juice in the human stomach has a pH of 2.0. This acidity is due to the secretion of protons into the stomach by the epithelial cells of the gastric mucosa.
(b)
To determine: The free energy change associated with the secretion of 1 mole of protons into gastric juice at 37°C.
Introduction: The transport of sodium and potassium ions across the membrane is an active transport process, which involves the hydrolysis of adenosine triphosphate (ATP) to provide energy. The gastric juice in the human stomach has a pH of 2.0. This acidity is due to the secretion of protons into the stomach by the epithelial cells of the gastric mucosa.
(c)
To determine: If proton transport can be driven by ATP hydrolysis at the ratio of one molecule of ATP per protein transported.
Introduction: The transport of sodium and potassium ions across the membrane is an active transport process, which involves the hydrolysis of adenosine triphosphate (ATP) to provide energy. The gastric juice in the human stomach has a pH of 2.0. This acidity is due to the secretion of protons into the stomach by the epithelial cells of the gastric mucosa.
(d)
To determine: The membrane potential that would be required to prevent proton to move back into the cell.
Introduction: The transport of sodium and potassium ions across the membrane is an active transport process, which involves the hydrolysis of adenosine triphosphate (ATP) to provide energy. The gastric juice in the human stomach has a pH of 2.0. This acidity is due to the secretion of protons into the stomach by the epithelial cells of the gastric mucosa.
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Becker's World of the Cell (9th Edition)
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