Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 8, Problem 8.5CC
Both the Na+/glucose symporter and the Na+/K+ pump move sodium ions across a membrane. How is the movement different for the two types of transporters?
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What determines the magnitude of flux across a membrane in a mediated-transport system?
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Ibogaine and cocaine inhibit the dopamine active transporter (DAT). This transporter is a secondary active transporter, and depends on the primary active transporter Na+/K+ ATPase. Ibogaine had a Kι = 2 μM, and cocaine a Kι = 0.64 μM respectively.
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For each type of membrane transport, know the following:– Is a transporter protein required? If so, what type?– Is there an energy requirement, and if so, what is the energy source?– What is the relative rate of solute transport based on molecule type? On concentration gradient?– What are examples of the types of solutes transported by carriers and channels?
Chapter 8 Solutions
Becker's World of the Cell (9th Edition)
Ch. 8 - What is the difference between the concentration...Ch. 8 - Prob. 8.2CCCh. 8 - A researcher is studying a fern that is shown to...Ch. 8 - How are carrier proteins and channel proteins...Ch. 8 - How would you determine whether a specific...Ch. 8 - Both the Na+/glucose symporter and the Na+/K+ pump...Ch. 8 - You are studying the energetics of transport of...Ch. 8 - True or False? Indicate whether each of the...Ch. 8 - Telling Them Apart. From the following list of...Ch. 8 - Mechanisms of Transport. For each of the following...
Ch. 8 - Prob. 8.4PSCh. 8 - Prob. 8.5PSCh. 8 - Prob. 8.6PSCh. 8 - QUANTITATIVE Sodium Ion Transport. A marine...Ch. 8 - Prob. 8.8PSCh. 8 - Prob. 8.9PSCh. 8 - QUANTITATIVE The Calcium Pump of the Sarcoplasmic...Ch. 8 - Inverted Vesicles. An important advance in...Ch. 8 - Ouabain Inhibition. Ouabain is a specific...
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- difference between channels and transporters is that O Only channels allow for the passage of solutes against their electrochemical gradient. OTransporters allow for a greater rate of transport across a membrane than channels do. O Only channels allow for the transport of ions. Transporters must undergo a conformational change upon binding to the solute.arrow_forwardHow do neutral solutes move across the plasma membrane? Can the polarmolecules also move across it in the same way? If not, then how are thesetransported across the membrane?arrow_forwardthe maximal rate of solute movement during diffusion is greater than during mediated transport true or false?arrow_forward
- What might determine the value for the maximal flux of a mediated transport?arrow_forwardName the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3−) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms. What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forwardName the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3 −) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms.What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forward
- the sodium channel exchanger NCX transports sodium into and calcium out of cardiac muscle cells. Describe why this itransporter is classified as secondary active transport?arrow_forwardDiscuss carrier-mediated transport. How could you experimentally distinguish between the different types of carrier-mediated transport?arrow_forwardA membrane separates Solution A and Solution B. The membrane has a permeability of 2 x 105 cm/s to urea and has a surface area of 5 cm2. The concentration of urea in Solution A is 2 mg/mL. The initial rate of net diffusion of urea is 1 x 104 mg/s. What is the concentration of urea in Solution B?arrow_forward
- Why "Transporter are not very selective, and allow solutes to enter or leave the cell through channels or carriers composed of proteins" is true"?arrow_forwardAre symporters and antiporters always involved in active transport? Can't both solutes move in the same direction and be moving down their concentration gradient (and the same with antiporters)?arrow_forwardEven under isotonic conditions, there is a slow leakage of ions into animal cells. How does the plasma-membrane Na+/K+ ATPase enable animal cells to avoid osmotic lysis under isotonic conditions?arrow_forward
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The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license