Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 7, Problem 22PDQ

An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are in the following table.

AaBbCc 20 AaBbcc 20
aabbCc 20 aabbcc 20
AabbCc 5 Aabbcc 5
aaBbCc 5 aaBbcc 5

(a) Assuming simple dominance and recessiveness in each gene pair, if these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion?

(b) Answer part (a) again, assuming the three genes are so tightly linked on a single chromosome that no crossover gametes were recovered in the sample of offspring.

(c) What can you conclude from the actual data about the location of the three genes in relation to one another?

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An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table. 20 AaBbCc 20 AaBbcc 20 aabbCc 20 aabbcc 5 AabbCc 5 Aabbcc 5 aaBbCc 5 aaBbcc (a) If these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion, assuming simple dominance and recessiveness in each gene pair? (b) Answer part (a) again, assuming the three genes are so tightly linked on a single chromosome that no crossover gametes were recovered in the sample of offspring. (c) What can you conclude from the actual data about the location of the three genes in relation to one another?
An organism of the genotype AaBbCc was testcrossed to a triplyrecessive organism (aabbcc). The genotypes of the progeny are inthe following table.AaBbCc         20         AaBbcc          20aabbCc         20          aabbcc          20AabbCc         5           Aabbcc           5aaBbCc         5           aaBbcc            5 a.) Assuming simple dominance and recessiveness in each genepair, if these three genes were all assorting independently,how many genotypic and phenotypic classes would result inthe offspring, and in what proportion? b.) Answer part (a) again, assuming the three genes are sotightly linked on a single chromosome that no crossovergametes were recovered in the sample of offspring. c.) What can you conclude from the actual data about thelocation of the three genes in relation to one another?
Shown below is a pedigree for a completely penetrant trait called Adams syndrome in which babies are born blind. This trait occurs when an allele of the adams gene is associated with ≥200 tandem trinucleotide repeats (the normal number is 10). First cousins, III-1 and III-2 married and their first child (IV-1) was blind. For their next child, they decided to do in vitro fertilization with III-1's sperm and III-2's eggs to generate six embryos (labeled E1-6). When each embryo contained eight cells, a single cell was removed and genomic DNA was isolated. PCR reactions using primers that flank the trinucleotide repeat region were then performed and the resulting fragments were fractionated on an agarose gel. PCR reactions using genomic DNA from III-1, III-2 and IV-1 were included as controls. The DNA was visualized using a fluorescent dye and the gel is shown below. Based on this information, select the best answer from the list to the questions below. || E1 = embryo 1 IV E1 E2 E3 E4 E5…

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