Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 7, Problem 2PDQ
Review the Chapter Concepts list on page 120. Most of these center on the process of crossing over between linked genes. Write a short essay that discusses how crossing over can be detected and how the resultant data provide the basis of chromosome mapping.
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Genes Q, R, and S are on the same chromosome. The crossoverfrequency between S and Q is 5%, the crossover frequency betweenQ and R is 30%, and the crossover frequency between R and S is35%. Use this information to create a linkage map for thechromosome
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Chapter 7 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 7 -
CASE STUDY | Links to autism
As parents of an...Ch. 7 -
CASE STUDY | Links to autism
As parents of an...Ch. 7 - CASE STUDY | Links to autism As parents of an...Ch. 7 -
CASE STUDY | Links to autism
As parents of an...Ch. 7 -
HOW DO WE KNOW?
1. In this chapter, we focused on...Ch. 7 -
CONCEPT QUESTION
2. Review the Chapter Concepts...Ch. 7 - Describe the cytological observation that suggests...Ch. 7 - Why does more crossing over occur between two...Ch. 7 - Why is a 50 percent recovery of single-crossover...Ch. 7 - Why are double-crossover events expected less...
Ch. 7 - What is the proposed basis for positive...Ch. 7 - What three essential criteria must be met in order...Ch. 7 - The genes dumpy wings (dp), clot eyes (cl), and...Ch. 7 - Colored aleurone in the kernels of corn is due to...Ch. 7 - In the cross shown here, involving two linked...Ch. 7 - In a series of two-point map crosses involving...Ch. 7 -
13. Two different female Drosophila were...Ch. 7 -
14. In Drosophila, a cross was made between...Ch. 7 -
15. A cross in Drosophila involved the recessive,...Ch. 7 -
16. Drosophila melanogaster has one pair of sex...Ch. 7 -
17. Drosophila females homozygous for the third...Ch. 7 - In Drosophila, the two mutations Stubble bristles...Ch. 7 -
19. A female of genotype
produces 100 meiotic...Ch. 7 - In a plant, fruit color is either red or yellow,...Ch. 7 - In Drosophila, Dichaete (D) is a mutation on...Ch. 7 - An organism of the genotype AaBbCc was testcrossed...Ch. 7 - Based on our discussion of the potential...Ch. 7 - Prob. 24PDQCh. 7 - DNA markers have greatly enhanced the mapping of...Ch. 7 - Are sister chromatid exchanges effective in...
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- What is FISH? Briefly describe how it works How is FISH used to characterize chromosomal translocations associated with certain genetic disorders and specific types of cancers?arrow_forwardFor questions 22 through 30, please refer to the pictures below: Normal B B B C D D D D' E E 22 23 24 B D G. Y D M H. B C E 25 26 27 28 B D Break through centromere B B A D 29 30 Identify the type of chromosomal aberration in each number above. Please refer to the choices below. Reciprocal translocation Robertsonian translocation Isochromosome Terminal deletion Interstitial deletion Duplication Pericentric inversion Ring chromosome Marker chromosome Paracentric inversionarrow_forwardIn Drosophila, bar-shaped eyes (B), scalloped wings (S), crossvein-less wings (W), and eye Color (C) are located on the X chromosome. The recombination frequency of each gene is indicated on the table. Construct a chromosome map. Identify the first gene, second gene, third gene, and the fourth gene Write down the distances between genearrow_forward
- In corn, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of the corn plants (i.e the tassel) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile corn plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male sterile lines Using the cardboard chips, simulate the crosses indicated below. Give the genotypes and phenotypes of the offsprings in each cross, and properly label the nucleus and the cytoplasm of each individual in the cross Legend male sterile cytoplasm Male fertile cytoplasm FF nucleus Ff nucleus ff nucleus A. Male sterile female x FF male Explain the phenotype of the offspring B. Male sterile female x Ff male Explain the phenotype of the offspringarrow_forwardIn an electrophoretic gel across which is applied a powerful electrical alternating pulsed field, the DNA of the haploid fungus Neurospora crassa (n = 7) moves slowly but eventually forms seven bands, which represent DNA fractions that are of different sizes and hence have moved at different speeds. These bands are presumed to be the seven chromosomes. How would you show which band corresponds to which chromosome?arrow_forwardThe mutations called bobbed in Drosophila result from variable reductions (deletions) in the number of amplified genes coding for rRNA. Researchers trying to maintain bobbed stocks have often documented their tendency to revert to wild type in successive generations. Propose a mechanism based on meiotic recombination which could account for this reversion phenomenon. Why would wild-type flies become more prevalent in Drosophila cultures?arrow_forward
- crossing over within a pericentric inversion produces chromosomes that have extra copies of some genes and no copies of other genes. The fertilization of gametes containing chromosomes with duplications or deletions often result in children with syndromes characterized by developmental delay, intellectual disability, abnormal development of organ systems, and early death. Maarit Jaarola and colleagues examined individual sperm cells of a male who was heterozygous for a pericentric inversion on chromosome 8 and determined that crossing over took place within the pericentric inversion in 26% of the meiotic divisions (M. Jaarola, R. H. Martin, and T. Ashley. 1998. American Journal of Human Genetics 63:218–224). Assume that you are a genetic counselor and that a couple seeks counseling from you. Both the man and the woman are phenotypically normal, but the woman is heterozygous for a pericentric inversion on chromosome 8. The man is karyotypically normal. What is the probability that this…arrow_forwardIn Drosophila the genes A B D are linked. You cross a strain that is homozygous for d with a strain that is homozygous for ab. Below are the phenotypes and progeny of a test cross. Give the correct order of the genes in the chromosome and determine the map distances between genes. Phenotype Number ABd 389 abD 413 ABD 60 abd 68 aBd 29 AbD 34 Abd 3 aBD 4arrow_forwardFor this particular family, what is the recombination rate between the D17S74 marker and the breast cancer gene? Lets say that at age 45 the third granddaughter III-3, is diagnosed with breast cancer. Now recalculate the recombination rate between the marker locus D17S74 and the breast cancer gene? Use only the 5 women in your analysis:the two daugthers in generation II and the three granddaughters in generation IIarrow_forward
- In corn, the genes v (virescent seedlings), pr (red aleurone), and bm (brown midrib) are all on chromosome 5, but not necessarily in the order given. The cross: v+ pr bm/ v pr+ bm+ with v pr bm/ v pr bm produces 1000 progeny with the following phenotypes: v+ pr bm 226 v pr+ bm+ 229 v+ pr bm+ 153 v pr+ bm 185 v+ pr+ bm 59 v pr bm+ 71 v+ pr+ bm+ 36 v pr bm 41 What is the gene order, and the (b) genetic map of these three genes?arrow_forwardConsider the following "pericentric" ("around the center") inversion. In one an individual, a simplified 8-gene sequence along one chromosome is 1234 5678 while a pericentric inversion occurred on their other homologous chromosome, resulting in the sequence 1265 4378 (the dot represents the centromere). Draw these homologous chromosomes lined up (as during crossing over, in Prophase l). If a crossover event occurred between gene locus 3 and 4 (slicing between them) on the original chromosome, what would the crossover products look like? What would be the "problem" with each of the chromosomes that result?arrow_forwardIn tomato, the following genes are located on chromosome 2: + tall plant d dwarf plant + uniformly green leaves m mottled green leaves + smooth fruit p pubescent (hairy) fruit Results of the cross +++ / dmp and dmp / dmp were: + + + = 470 + m p = 1 + + p = 14 d + p = 25 d + + = 0 d m p = 441 + m + = 19 d m + = 30 Identify the single and double crossovers among the progeny.arrow_forward
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