Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 6, Problem 29RA
Summary Introduction
To review:
Carrier-mediated transport and its type.
Introduction:
Glucose, amino acids, lactic acids, and other organic compounds have to be transferred from the extracellular environment inside the cells for the production of energy. The transport of molecules through the lipid membrane of cells is done by various mechanism. Some molecules require energy for their transport and some directly diffuse through the membrane and so on. The lipid membrane has many protein channels that transport the molecules across the membrane.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Below find the structures for ibogaine and cocaine.
Ibogaine and cocaine inhibit the dopamine active transporter (DAT). This transporter is a secondary active transporter, and depends on the primary active transporter Na+/K+ ATPase. Ibogaine had a Kι = 2 μM, and cocaine a Kι = 0.64 μM respectively.
(a) Define secondary active transport.
(b) Is ibogaine an effective treatment for cocaine based on DAT binding?
Briefly describe, how P-type transporters helps in transporting ions?
(Subject: Biomembrane)
Distinguish between simple diffusion (SD), facilitated diffusion (FD), and active transport (AT) across a membrane for the following questions.
(a) Which processes are energy dependent?
(b) Which processes need some kind of carrier protein(s)?
(c) Which processes can be saturated by substrate?
(d) Which processes can establish a concentration gradient?
(e) How much energy does it take to transport an uncharged substrate in, if its starting inside concentration is 10-fold greater than outside?
Chapter 6 Solutions
Human Physiology
Ch. 6 - Describe the distribution of fluid in the body.Ch. 6 - Describe the composition of the extracellular...Ch. 6 - List the subcategories of passive transport and...Ch. 6 - Explain what is meant by simple diffusion and list...Ch. 6 - Prob. 4CPCh. 6 - Prob. 5CPCh. 6 - Explain how the body detects changes in the...Ch. 6 - Prob. 7aCPCh. 6 - Prob. 7bCPCh. 6 - Prob. 7cCP
Ch. 6 - Prob. 8CPCh. 6 - Prob. 9aCPCh. 6 - Prob. 9bCPCh. 6 - Explain the relationship of the resting membrane...Ch. 6 - Prob. 10bCPCh. 6 - Prob. 11CPCh. 6 - Prob. 12CPCh. 6 - The movement of water across a plasma membrane...Ch. 6 - Which of these statements about the facilitated...Ch. 6 - Prob. 3RACh. 6 - Prob. 4RACh. 6 - Blood plasma has an osmolality of about 300 mOsm....Ch. 6 - Prob. 6RACh. 6 - The most important diffusible ion in the...Ch. 6 - Prob. 8RACh. 6 - Prob. 9RACh. 6 - Prob. 10RACh. 6 - Prob. 11RACh. 6 - Prob. 12RACh. 6 - Prob. 13RACh. 6 - Prob. 14RACh. 6 - Which of the following questions regarding second...Ch. 6 - Prob. 16RACh. 6 - Prob. 17RACh. 6 - Compare the resting membrane potential of a neuron...Ch. 6 - Prob. 19RACh. 6 - Prob. 20RACh. 6 - Prob. 21RACh. 6 - Prob. 22RACh. 6 - Using the principles of osmosis, explain why...Ch. 6 - Prob. 24RACh. 6 - Prob. 25RACh. 6 - Prob. 26RACh. 6 - Prob. 27RACh. 6 - Prob. 28RACh. 6 - Prob. 29RACh. 6 - Prob. 30RACh. 6 - Using only the information in this chapter,...Ch. 6 - Prob. 32RACh. 6 - Prob. 33RACh. 6 - Suppose a semipermeable membrane separates two...Ch. 6 - Prob. 35RACh. 6 - Prob. 36RACh. 6 - Use the Nernst equation and the ion concentration...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Name the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3−) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms. What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forwardName the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3 −) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms.What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forwardName the three types of carrier proteins. Which of these can mediate secondary active transport?arrow_forward
- For each type of membrane transport, know the following:– Is a transporter protein required? If so, what type?– Is there an energy requirement, and if so, what is the energy source?– What is the relative rate of solute transport based on molecule type? On concentration gradient?– What are examples of the types of solutes transported by carriers and channels?arrow_forwardOuabain is a specific inhibitor of the active transport of sodium ions out of the cell and is therefore a valuable tool in studies of membrane transport mechanisms. Which of the following processes in your own body would you expect to be sensitive to inhibition by ouabain? Explain your answer in each case. a) Facilitated diffusion of glucose into a muscle cell b) Active transport of dietary phenylalanine across the intestinal mucosa c) Uptake of potassium ions by red blood cells d) Active uptake of lactose by the bacteria in your intestinearrow_forwardUniporters and ion channels support facilitated transport across cellular membranes. Although both are examples of facilitated transport, the rates of ion movement via an ion channel are roughly 104- to 105-fold faster than the rates of molecule movement via a uniporter. What key mechanistic difference results in this large difference in transport rate? What contribution to free energy (ΔG) determines the direction of transport?arrow_forward
- Uniporters and ion channels support facilitated transport across cellular membranes. Although both are examples of facilitated transport, the rates of ion movement via an ion channel are roughly 104 - to 105 -fold faster than the rates of molecule movement via a uniporter. What key mechanisticdifference results in this large difference in transport rate?What contribution to free energy (ΔG) determines the direction of transport?arrow_forwardWrite some properties of facillitated transport?arrow_forwardWhat would happen in each of the following cases where something related to intracellular transport is altered? Assume in each case that the protein involved is a soluble protein, not a membrane protein. State where each protein would be located and explain each of your answers. You add a signal sequence (for the Golgi) to the N-terminal end of a normally cytosolic protein. You change the hydrophobic amino acids in an ER signal sequence into other, hydrophobic, amino acids.arrow_forward
- The studies of Palade and colleagues used pulse chase labeling with radioactively labeled amino acids and auto radiography to visualize the location of newly synthesized proteins in pancreatic acinar cells. These early experiments provided invaluable information on protein synthesis and intercompartmental transport. New methods have replaced these early approaches, but two basic requirements are still necessary for any assay to study this type of protein transport. What are they, and how do recent experimental approaches meet these criteria?arrow_forwardDefine the terms (i) facilitated diffusion, (ii) primary active transport and (iii) secondary active transport. Identify which of these transport types the following are examples of: a) ATP/ADP translocase b) K^+ channels c) Bacteriorhodopsinarrow_forwardWhat might determine the value for the maximal flux of a mediated transport?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license