Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Question
Chapter 6, Problem 27RA
Summary Introduction
To review:
G-protein coupled receptors with their functions.
Introduction:
G-proteins are also called as guanine-
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What are G-protein-coupled receptors? Explain their function in regard to how particular regulatorymolecules influence different effector proteins in the membrane.
What are g-coupled protein receptors? Explain the role they play in cell physiology.
Is the term “G protein” just a shorter name for aG protein-coupled receptor?
Chapter 6 Solutions
Human Physiology
Ch. 6 - Describe the distribution of fluid in the body.Ch. 6 - Describe the composition of the extracellular...Ch. 6 - List the subcategories of passive transport and...Ch. 6 - Explain what is meant by simple diffusion and list...Ch. 6 - Prob. 4CPCh. 6 - Prob. 5CPCh. 6 - Explain how the body detects changes in the...Ch. 6 - Prob. 7aCPCh. 6 - Prob. 7bCPCh. 6 - Prob. 7cCP
Ch. 6 - Prob. 8CPCh. 6 - Prob. 9aCPCh. 6 - Prob. 9bCPCh. 6 - Explain the relationship of the resting membrane...Ch. 6 - Prob. 10bCPCh. 6 - Prob. 11CPCh. 6 - Prob. 12CPCh. 6 - The movement of water across a plasma membrane...Ch. 6 - Which of these statements about the facilitated...Ch. 6 - Prob. 3RACh. 6 - Prob. 4RACh. 6 - Blood plasma has an osmolality of about 300 mOsm....Ch. 6 - Prob. 6RACh. 6 - The most important diffusible ion in the...Ch. 6 - Prob. 8RACh. 6 - Prob. 9RACh. 6 - Prob. 10RACh. 6 - Prob. 11RACh. 6 - Prob. 12RACh. 6 - Prob. 13RACh. 6 - Prob. 14RACh. 6 - Which of the following questions regarding second...Ch. 6 - Prob. 16RACh. 6 - Prob. 17RACh. 6 - Compare the resting membrane potential of a neuron...Ch. 6 - Prob. 19RACh. 6 - Prob. 20RACh. 6 - Prob. 21RACh. 6 - Prob. 22RACh. 6 - Using the principles of osmosis, explain why...Ch. 6 - Prob. 24RACh. 6 - Prob. 25RACh. 6 - Prob. 26RACh. 6 - Prob. 27RACh. 6 - Prob. 28RACh. 6 - Prob. 29RACh. 6 - Prob. 30RACh. 6 - Using only the information in this chapter,...Ch. 6 - Prob. 32RACh. 6 - Prob. 33RACh. 6 - Suppose a semipermeable membrane separates two...Ch. 6 - Prob. 35RACh. 6 - Prob. 36RACh. 6 - Use the Nernst equation and the ion concentration...
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- Outline the three general means by which binding of a water soluble extracellular chemical messenger to its matching surface membrane receptor brings about the desired intracellular response.arrow_forwardSecond-messenger systems ultimately bring about the desired cell response by inducing a change in the shape and function of particular designated intracellular proteins. (True or false?)arrow_forwardWhen a G-coupled receptor is activated, does the By subunit activate any pathways? If yes, describe which pathway. If no, then why do you think the By subunit exists?arrow_forward
- Describe the common architecture of G protein-coupled receptors. Illustrate your answer with reference to the domains that facilitate signal transduction across the plasma membranearrow_forwardWhat are G-protein coupled receptors? How does ligand binding activates GPCR (include in your answer, the types of G-proteins and the second messenger systems involved in the translation of a pharmacological response when a ligand binds to GPCR)?arrow_forwardWould nitrosylation of cysteine or ubiquitination of lysine disrupt binding the most in a G protein coupled receptor?arrow_forward
- Continuous exposure of a G protein-coupled receptor to its ligand leads to a phenomenon known as desensitization. Describe several molecule mechanisms for receptor desensitizationarrow_forwardContinuous exposure of a Gαs protein coupled receptor to its ligand leads to a phenomenon known as desensitization. Describe several molecular mechanisms for receptor desensitization. How can a receptor be reset to its original sensitized state? What effect would a mutant receptor lacking serine or threonine phosphorylation sites have on a cell?arrow_forwardWhat are the three steps by which receptor tyrosine kinases typically convey an extracellular signal to another intracellular enzyme?arrow_forward
- Draw the general structural features of a G-protein coupled receptor (GPCR)arrow_forwardThe Structure of the acetylcholine receptor is shown below: A. Knowing the amino acid sequence of this protein, what tool would you use to identify the membrane-spanning region? Explain how it works.arrow_forwardDescribe the difference between agonist and antagonist. What is a role of G-protein coupled receptors?arrow_forward
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