Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Question
Chapter 6, Problem 14RA
Summary Introduction
To explain:
Membrane potential when gated ion channels of sodium and calcium ions open.
Introduction:
Membrane potential is due to the disparities in concentration and permeabilities of ions across the membrane. There is an unequal distribution of ions in the membrane which leads to the development of electrical charge inside the membrane.
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The resting membrane potential of a neuron or muscle cell is a. equal to the potassium equilibrium potential. b. equal to the sodium equilibrium potential. c. somewhat less negative than the potassium equilibrium potential. d. somewhat more positive than the sodium equilibrium potential. e. not changed by stimulation.
Determine whether each statement is true or false. If a statement is false, explain why.
A. Voltage gated sodium channels are quick to open and slow to close, while
voltage gated potassium channels are quick to open and slow to close.
6. Before a second action potential can be generated, the concentration of sodium
and potassium on either side of the cell membrane must be fully restored.
C. The strength of an action potential is represented by the amplitude of the wave.
A stronger stimulus will generate an action potential with a higher peak than a
weaker stimulus.
D.. Action potentials travel in a non-decremental manner down the axon, with the
voltage constantly being regenerated along the way, unlike graded potentials
which quickly diminish over short distances.
E. Contiguous conduction is faster than saltatory conduction.
F. Action potentials originate in the axon hillock and travel down the axon to the
terminal boutons (pre-synaptic axon terminals).
The resting membrane potential results fromA. uneven distribution of ions across the cell membrane only.B. differences in membrane permeability to Na+ and K+ onlyC. activity of the sodium/potassium pump only.D. uneven distribution of ions across the cell membrane, differences in membrane permeability to Na+ and K+, and sodium/potassium pump activity
Chapter 6 Solutions
Human Physiology
Ch. 6 - Describe the distribution of fluid in the body.Ch. 6 - Describe the composition of the extracellular...Ch. 6 - List the subcategories of passive transport and...Ch. 6 - Explain what is meant by simple diffusion and list...Ch. 6 - Prob. 4CPCh. 6 - Prob. 5CPCh. 6 - Explain how the body detects changes in the...Ch. 6 - Prob. 7aCPCh. 6 - Prob. 7bCPCh. 6 - Prob. 7cCP
Ch. 6 - Prob. 8CPCh. 6 - Prob. 9aCPCh. 6 - Prob. 9bCPCh. 6 - Explain the relationship of the resting membrane...Ch. 6 - Prob. 10bCPCh. 6 - Prob. 11CPCh. 6 - Prob. 12CPCh. 6 - The movement of water across a plasma membrane...Ch. 6 - Which of these statements about the facilitated...Ch. 6 - Prob. 3RACh. 6 - Prob. 4RACh. 6 - Blood plasma has an osmolality of about 300 mOsm....Ch. 6 - Prob. 6RACh. 6 - The most important diffusible ion in the...Ch. 6 - Prob. 8RACh. 6 - Prob. 9RACh. 6 - Prob. 10RACh. 6 - Prob. 11RACh. 6 - Prob. 12RACh. 6 - Prob. 13RACh. 6 - Prob. 14RACh. 6 - Which of the following questions regarding second...Ch. 6 - Prob. 16RACh. 6 - Prob. 17RACh. 6 - Compare the resting membrane potential of a neuron...Ch. 6 - Prob. 19RACh. 6 - Prob. 20RACh. 6 - Prob. 21RACh. 6 - Prob. 22RACh. 6 - Using the principles of osmosis, explain why...Ch. 6 - Prob. 24RACh. 6 - Prob. 25RACh. 6 - Prob. 26RACh. 6 - Prob. 27RACh. 6 - Prob. 28RACh. 6 - Prob. 29RACh. 6 - Prob. 30RACh. 6 - Using only the information in this chapter,...Ch. 6 - Prob. 32RACh. 6 - Prob. 33RACh. 6 - Suppose a semipermeable membrane separates two...Ch. 6 - Prob. 35RACh. 6 - Prob. 36RACh. 6 - Use the Nernst equation and the ion concentration...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Epilepsy is a condition which results in seizures stemming from excessive or abnormal activity of neurons. This can occur either from hyperexcitability of excitatory neurons, or impairment of inhibitory neurons. That is to say, either the excitatory pathways become overactive, or the inhibitory pathways, designed to temper the excitatory pathways, are not active enough. Much of the research done on epilepsy focuses on voltage-gated sodium channels, and to date over 700 different mutations to the channel have been identified as playing a role in epilepsy. The means by which these mutations contribute to epilepsy is quite complex, but for the sake of this CAL, let's simplify and apply what we have learned so far to identify potential mechanisms for this condition. In what way could voltage-gated sodium channels be affected in excitatory neurons which would increase the likelihood of the neuron firing an action potential? (one correct answer) The inactivation gate is slower to close. The…arrow_forwardMark the following statements as true or false. If a statement is false, correct it to make a true statement. a. The resting membrane potential refers to the voltage difference across the membranes of excitable cells at rest. b. The concentration of Na+ is highest in the cytosol, and the concentration of K+ is highest in the extracellular fluid. c. The Na+>K+ pumps and gated channels maintain the Na+ and K+ gradients necessary for action potentials to occur. d. A depolarization is a change in membrane potential that makes the potential less negative. e. A local potential is a change in membrane potential that conducts the long-distance signals of the nervous systemarrow_forwardVoltage-gated Na+ channels open upon reaching what state? a. resting potential b. threshold c. repolarization d. overshootarrow_forward
- Figure 1 shows the action potential graph recorded from a rat neurone and the potential changes obtained from the rat neurone when the concentration of potassium ([K*]out) and calcium ([Ca²+]out) are varied extracellularly in the bathing solution. (i) In the resting state, is the neuronal permeability to potassium more than, less than or equal to that of the permeability to calcium? Explain your answer. (ii) Vm 'The calcium ion concentrations are lower inside the cell than outside.' Justify this statement based on the graphs and the Nernst equation assuming the temperature is at 25 °C. Vm 30 0 -30 30 0- -30 0 50 AP overshoot [K+ lout 100 150 time (msec) 30 RP Figure 1 0- -30 AP overshoot RP 200 250 AP overshoot {Ca²+ Jout RParrow_forwardWhich of the following statements is TRUE of the action potential? A. At the peak of the action potential there are approximately an equal amount of open voltage gated sodium and potassium channels B. To reach threshold the action potential requires the activity of sodium potassium pump C. During the rising phase (prior to the peak) of the action potential more voltage gated sodium channels are open than voltage gated potassium channels D. None of the choice options are TRUE of the action potential E. The overshoot phase (below resting membrane potential) is a result of voltage gated sodium channels taking a long time to close.arrow_forwardReversal potential of ACh receptors is 0mV. Equilibrium potentials of Na* and K* are +60mV and -90mV, respectively. A. Calculate emf for Nat and K* at -30mV. B. Is ACh receptor current at -30mV inward or outward? Is it causing depolarization or hyperpolarization?arrow_forward
- Which of the following primarily reflects the opening of voltage-gated Na+ channels? A. The resting membrane potential B. The depolarization phase of the action potential C. The threshold potential D. The repolarization phase of the action potential E. All of the abovearrow_forwardThe equilibrium potential for K* in neurons is ordinarily nearest- A. the equilibrium potential for Na* B. resting potential C. reversal potential for the EPSP D. the peak of the action potentialarrow_forwardCalcium is highly regulated molecule in cells due to its importance in cell signaling. A. Briefly explain the role of calcium in the excitation-concentration coupling in the muscles B. Based on your description in part A, if the sensor of calcium stopped working, which step would be affect and why?arrow_forward
- On the graph above, when do the sodium ion channels close? Select one: a. between 0.2 ms and 0.5 ms, which is when depolarization occurs b. at 0.2 ms, which is when depolarization occurs c. at 0.5 ms, which is when repolarization begins d. between 0.5 ms and 0.8 ms, which is when repolarization occursarrow_forwarddendrotoxins, produced by the mamba snakes are inhibitors of the voltage gated k+ channel. what phase of the action potential with this toxin effect? how would it affect ion permeability during this phase howard ion movement be affected?arrow_forwardMatch the description with the statement that best describes the following statements hyperpolarization repolarization depolarization A. usually corresponds to opening of voltage-gated potassium channels B. any change in the membrane potential that moves the membrane potential to a value more positive than the resting potential (eg from -70mV to +35mV) C. any change in the membrane potential that moves the membrane potential to a value more negative than the resting potential (eg from -70mV to -85mV)arrow_forward
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