Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 6, Problem 10RA
Summary Introduction
To determine:
The characteristic features of
Introduction:
There are two types of pumps present: Symport pumps and antiport pumps. In an antiport pump, one substance is transported in one direction and the other is transported in the opposite direction. For example, the sodium-potassium pump is an example of antiport. In symport pumps the substance moves from a higher concentration to a lower concentration.
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In nerve cells, sodium-potassium pumps exchange two K^++start superscript, plus, end superscript for three Na^++start superscript, plus, end superscript across the cell membrane. What is the primary purpose of this exchange?
a.To increase the concentration of K+ outside the cell
b.To increase the concentration of K+ outside the cell
c.To propagate an action potential
d.To increase the concentration of Na+ inside the cell
Explain the mechanism of action of the Na+/K+ pump. If these pumps became non-functional due to a genetic mutation, what do you think would be the expected effect on the electrochemical membrane potential of the cell? Explain your reasoning.
Which of these statements about ion movement through the plasmamembrane is true?a. Movement of Na+ out of the cell requires energy (ATP).b. When Ca2+binds to proteins in ion channels, the diffusion of Na+into the cell is inhibited.c. Specific ion channels regulate the diffusion of Na+ through theplasma membrane.d. All of these are true
Chapter 6 Solutions
Human Physiology
Ch. 6 - Describe the distribution of fluid in the body.Ch. 6 - Describe the composition of the extracellular...Ch. 6 - List the subcategories of passive transport and...Ch. 6 - Explain what is meant by simple diffusion and list...Ch. 6 - Prob. 4CPCh. 6 - Prob. 5CPCh. 6 - Explain how the body detects changes in the...Ch. 6 - Prob. 7aCPCh. 6 - Prob. 7bCPCh. 6 - Prob. 7cCP
Ch. 6 - Prob. 8CPCh. 6 - Prob. 9aCPCh. 6 - Prob. 9bCPCh. 6 - Explain the relationship of the resting membrane...Ch. 6 - Prob. 10bCPCh. 6 - Prob. 11CPCh. 6 - Prob. 12CPCh. 6 - The movement of water across a plasma membrane...Ch. 6 - Which of these statements about the facilitated...Ch. 6 - Prob. 3RACh. 6 - Prob. 4RACh. 6 - Blood plasma has an osmolality of about 300 mOsm....Ch. 6 - Prob. 6RACh. 6 - The most important diffusible ion in the...Ch. 6 - Prob. 8RACh. 6 - Prob. 9RACh. 6 - Prob. 10RACh. 6 - Prob. 11RACh. 6 - Prob. 12RACh. 6 - Prob. 13RACh. 6 - Prob. 14RACh. 6 - Which of the following questions regarding second...Ch. 6 - Prob. 16RACh. 6 - Prob. 17RACh. 6 - Compare the resting membrane potential of a neuron...Ch. 6 - Prob. 19RACh. 6 - Prob. 20RACh. 6 - Prob. 21RACh. 6 - Prob. 22RACh. 6 - Using the principles of osmosis, explain why...Ch. 6 - Prob. 24RACh. 6 - Prob. 25RACh. 6 - Prob. 26RACh. 6 - Prob. 27RACh. 6 - Prob. 28RACh. 6 - Prob. 29RACh. 6 - Prob. 30RACh. 6 - Using only the information in this chapter,...Ch. 6 - Prob. 32RACh. 6 - Prob. 33RACh. 6 - Suppose a semipermeable membrane separates two...Ch. 6 - Prob. 35RACh. 6 - Prob. 36RACh. 6 - Use the Nernst equation and the ion concentration...
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- Here is a chloride cell in the gill epithelium of a fish. For reference, NKA = Na+/K+ ATPaseNKCC = Na+/K+/Cl- cotransporter. CFTR allows for movement of Cl- from inside the cell out into the water down a concentration gradient. Which of the following would be true of CFTR? A. It is a primary active transporter. B. It is a symporter. C. It is a secondary active transporter. D. It is a channel that allows for facilitated diffusion.arrow_forwardDescribe the contribution of each of the following to establishing and maintaining membrane potential: (a) the Na+K+ pump, (b) passive movement of K+ across the membrane, (c) passive movement of Na+ across the membrane, and (d) the large intracellular anions.arrow_forwardThe rate at which the Na+K+ pump operates is not constant but is controlled by a combined effect of changes in ICF Na+ concentration and ECF K+ concentration. Do you think the changes in both ICF Na+ and ECF K+ concentration following a series of action potentials in a neuron would accelerate, slow down, or have no effect on the Na+K+ pumps in this cell?arrow_forward
- A rise in the intracellular Ca2+ concentration causes muscle cells to contract. in addition to an ATP- driven Ca2+ pump, muscle cells that contract quickly and regularly, such as those of the heart, have an additional type of Ca2+ pump—an antiport that exchanges Ca2+ for extracellular Na+ across the plasma membrane. The majority of the Ca2+ ions that have entered the cell during contraction are rapidly pumped back out of the cell by this antiport, thus allowing the cell to relax. ouabain and digitalis are used for treating patients with heart disease because they make heart muscle cells contract more strongly. both drugs function by partially inhibiting the Na+ pump in the plasma membrane of these cells. can you propose an explanation for the effects of the drugs in the patients? What will happen if too much of either drug is taken?arrow_forwardIf the concentration of a solute is the same both inside and outside the cell, what might you expect with regard to its transport by a membrane protein? A. Since there is no concentration gradient, no transport either in or out of the cell is possible. B. The transport protein has been saturated. C. The solute must be phosphorylated with a phosphate group from ATP before further transport can occur. D. Movement of the solute across the membrane could occur and cause accumulated on one side of the membrane by an active transport protein. The concerted model of allosteric regulation is different from the sequential model, because: A. The concerted model is used to explain homotropic effects B. The sequential model is used to explain heterotropic effects C. Both A and B D. Neither A nor Barrow_forwardThe contraction of cardiac muscle cells results from the increase in Ca?+ levels in the cytosol. For these cells to relax, an antiport removes Ca?+ from the cytosol for every Nat that is taken in. Digitalis is a drug that is used to make the heart contract more strongly. This drug partially inhibits the Na*-K* ATPase in the cardiac cells. Applying the concepts from membrane transport, answer the following: a. Propose an explanation for the drug's effect. b. What will likely happen if too much of the drug is taken in? Why do you say so?arrow_forward
- The Na/K pump in epithelium cells that line the gut is an example of ______ transport and helps __ Select one: a. active, prevent the movement of Cl- outside the cell b. active, prevent the movement of Cl- inside the cell c. active, prevent the movement of Na+ outside the cell d. passive, prevent the movement of Cl- outside the cell e. passive, prevent the movement of Cl- inside the cellarrow_forwardSodium/glucose cotransporters on intestinal cells move glucose from the intestinal lumen (low glucose concentration) to inside the cell (high glucose concentration). Which of the following would increase the rate of glucose transport into the cell? a. Increase the intracellular glucose concentration. b. Decrease the extracellular glucose concentration. c. Decrease the extracellular Na+ concentration. d. Increase the extracellular Na+ concentration.arrow_forwardWhich of the following is incorrect about membrane transport systems? a. Glucose transport in red blood cells is a uniport system b. The Na+/K+ ATPase is an antiport system c. The H+/K+ ATPase is an active transport system d. The chloride-bicarbonate exchanger in erythrocytes is a uniport systemarrow_forward
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