Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 5, Problem 45P
| a. | In ordered tetrad analysis, what is the maximum RF that you could observe between |
| a gene and the centromere? (Hint: What RF would you observe between a gene and | |
| the centromere if the gene were distant enough from the centromere so that at least | |
| one crossover, and often more than one crossover, occurs between them in every | |
| meiosis?) | |
| b. | Can a gene and the centromere be unlinked? Explain. |
| c. | Suppose in an ordered tetrad analysis you observe an RF of 30% between a gene and |
| the centromere. Given your answer to part (a), do think that 30 m.u. is an accurate | |
| estimate of the distance between the gene and the centromere? |
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Students have asked these similar questions
2) A. Explain how polyribosomes form.
B. Why might you expect the insertion of 3 DNA base pairs to be less disruptive than th
deletion of a single base pair?
C. Compare and contrast mitosis and meiosis with respect to their genetic outcomes?
D. What are the possible consequences of non-disjunction during cell division?
E. How does meiosis increase genetic diversity in populations?
We have discussed meiosis in yeast. One ascus e one melotic event.
Two haploid yeast strains are crossed together, one wild type, the other mutant for 2 linked genes. The resulting diploid strain
undergoes melosis eventually (=many meiotic events > many asci).
A. What will the results be if the 2 genes are very far away from each other (certainly more than 50 map units)?
B. What will the results be if the two genes are right next to each other, "no distance at all, zero distance"?
(Explain your answers).
Results here are patterns of asci and their percentages. Like for example "50% tetratypes, 0% ditypes", etc. If you forgot what a
ditype or a tetratype is, you can illustrate them like that.
F
O
>
a. Draw the structure of the acentromeric chromosome using a line and letters to designate
loci in their appropriate order.
b. Show the structure of the two chromosomes following the second meiotic division that
were not involved in the recombination event. Draw these chromosomes using lines and
letters to designate the loci in their proper order.
m
D
B
Chapter 5 Solutions
Genetics: From Genes to Genomes
Ch. 5 - Choose the phrase from the right column that best...Ch. 5 - a. A Drosophila male from a true-breeding stock...Ch. 5 - Prob. 3PCh. 5 - The Punnett square in Fig. 5.4 shows how Mendels...Ch. 5 - In mice, the dominant allele Gs of the X-linked...Ch. 5 - In Drosophila, males from a true-breeding stock...Ch. 5 - If the a and b loci are 20 m.u. apart in humans...Ch. 5 - CCDD and ccdd individuals were crossed to each...Ch. 5 - In mice, the autosomal locus coding for the...Ch. 5 - In a particular human family, John and his mother...
Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a shows chromosomes during prophase of...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - Prob. 40PCh. 5 - Prob. 41PCh. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 43PCh. 5 - This problem leads you through the derivation of a...Ch. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - Prob. 46PCh. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Figure 5.29 shows mitotic recombination leading to...Ch. 5 - A diploid strain of yeast has a wild-type...Ch. 5 - In Drosophila, the yellow y gene is near the...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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- a. Manually, using a pencil, draw a cell in anaphase II from an organism in which 2n = 2 and each chromosome is metacentric. b. Given that each G1 nucleus from this organism contains 16 picograms of DNA, how many picograms of chromosomal DNA would you expect in the cell shown here?arrow_forwardAn individual is heterozygous for a reciprocal translocation, with the following chromosomes: A • B C D E F A • B C V W X R S T • U D E F R S T • U V W X a. Draw a picture of these chromosomes pairing in prophase I of meiosis. b. Draw the products of alternate, adjacent-1, and adjacent-2 segregations. c. Explain why the fertility of this individual is likely to be less than the fertility of an individual without a translocation.arrow_forwardb. An example of autosome and heterochromosome c. An example of homologous chromosome, sister chromatid and centromere. d. The total number of chromosomes in a metaphase kangaroo cell. e. A sentence to explain the difference between the terms gene and allele that might apply to this species. 5) Suppose that in a species of flowering plant, we cross a plant with red flowers with a short stem with a plant with blue flowers with a long stem. The offspring all have mauve flowers and a long stem. The two characters, flower color and stem length, are found on different chromosomes. What can you conclude about the mode of inheritance of each of the characteristics of this plant species? Incomplete dominance or codominance: C"C", simple A/a dominance b If a progeny with long-stemmed mauve flowers from FI is crossed with a plant with short-stemmed mauve flowers, what proportion of the progeny will have the same genotype as either of the parents? Compulsory Punnett grid. ONA and the principles…arrow_forward
- Sketch a series of diagrams showing each of the following, making sure to end each series with haploid cells:(a) How a pair of alleles for a single locus segregate in meiosis(b) How the alleles of two unlinked loci assort independently in meiosis(c) How the alleles of two linked loci undergo genetic recombinationarrow_forwardShown below are photomicrographs of Rhoeo tradescantia cells undergoing meiosis. Answer the following question for each of the photomicrograph: a. Identify the cytogenetic abnormality observed (ex. ring, chain, laggard, bridge) b. Identify the meiotic stage in which these aberrations are observed (as shown in the photomicrograph) c. Explain how these aberrations are formed d. Will this result to sterile or fertile gametes? Explain.arrow_forward3) A. How are the following proteins involved in cell division: condensing, cohesin, kinetochore complex, tubulin? B. Why does phenotype not always reveal genotype? C. How can Mendel's postulates of segregation and independent assortment be explained by meiosis? D. Explain the genotypic and phenotypic ratios predicted when performing a monohybrid and a dihybrid cross of heterozygotes? E. How can you use the product rule and sum rule to calculate the probability of a particular genotype resulting from crossing parents of specific genotypes?arrow_forward
- Shown below are photomicrographs of Rhoeo tradescantia cells undergoing meiosis. Answer the following question for each of the photomicrographs: Identify the cytogenetic abnormality observed (ex. ring, chain, laggard, bridge). Identify the meiotic stage in which these aberrations are observed (as shown in the photomicrograph). Explain how these aberrations are formed and relate to the possible causal mutation(s). Will this result to sterile and/or fertile gametes? Explain.arrow_forwarda. What is the diploid number of chromosomes for a human? b. What is the haploid number of chromosomes for a human? Which cells are considered diploid, gametes or somatic cells? C. d. Which cells are considered haploid, gametes or somatic cells?arrow_forwardIn com, male sterility is controlled by maternal cytoplasmic elements. However, the presence of a nuclear fertility restorer gene (F_) restores fertility to male sterile lines. a. What are the crosses male sterile female x FF male? Give the genotypes and phenotypes of the offspring in each cross. Explain.arrow_forward
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