Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 5, Problem 28P
a. In Drosophila, crosses between F1 heterozygotes of the form A b / a B always yield the same ratio of
b. If you intercrossed F1 heterozygotes of the form A b / a B in mice, the phenotypic ratio among the F2 progeny would vary with the map distance between the two genes. Is there a simple way to estimate the map distance based on the frequencies of the F2 phenotypes, assuming rates of recombination are equal in males and females? Could you estimate map distances in the same way if the mouse F1 heterozygotes were A B / a b?
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1. Please consider the following pedigree.
I
1
2
II
1
a) Assume that colour is controlled by a single sex-influenced gene where orange is expressed preferentially in females. Individuals I-1 and I-2 are homozygous
for orange and blue respectively. Which individual/s in generation II will be blue?
b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be orange?
1. Please consider the following pedigree.
I
1
II
1
a) Assume that colour is controlled by a single sex-influenced gene where green is expressed preferentially in males. Individuals I-1 and I-2 are homozygous for
red and green respectively. Which individual/s in generation II will be red?
b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be green?
EC1. In drosophila the cw (curly wings) gene and eb (ebony body) genes are found on the same chromosome 20 map units apart. A cross was made between an ebony bodied parental strain and a curly winged parental strain and the F1’s were test crossed.
a) What are the genotypes of the parental strains?
b) What are the genotypes of the F1’s?
c) What is the genotype of the tester strain?
d) What progeny phenotypes and genotypes do you expect, and in what proportions? For phenotypes use the mutant phenotype for any that the flies have, and wild-type if they have none.
EC2. Here is a tetrad produced by mating a H Y strain to an h y strain.
a) What is the tetrad type?
b) What has recombined with what?
EC3. In corn, a dihybrid for the recessive genes a and b is test-crossed. The distribution of the phenotypes is as follows:
A B 122A b 118a B 81a b 79
a) Do the genes appear to be sorting independently? Look at map units here.
b) Test your hypothesis with a chi-squared test.
Chapter 5 Solutions
Genetics: From Genes to Genomes
Ch. 5 - Choose the phrase from the right column that best...Ch. 5 - a. A Drosophila male from a true-breeding stock...Ch. 5 - Prob. 3PCh. 5 - The Punnett square in Fig. 5.4 shows how Mendels...Ch. 5 - In mice, the dominant allele Gs of the X-linked...Ch. 5 - In Drosophila, males from a true-breeding stock...Ch. 5 - If the a and b loci are 20 m.u. apart in humans...Ch. 5 - CCDD and ccdd individuals were crossed to each...Ch. 5 - In mice, the autosomal locus coding for the...Ch. 5 - In a particular human family, John and his mother...
Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a shows chromosomes during prophase of...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - Prob. 40PCh. 5 - Prob. 41PCh. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 43PCh. 5 - This problem leads you through the derivation of a...Ch. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - Prob. 46PCh. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Figure 5.29 shows mitotic recombination leading to...Ch. 5 - A diploid strain of yeast has a wild-type...Ch. 5 - In Drosophila, the yellow y gene is near the...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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- a. In a type of plant, pink flowers (P) is dominant over white flowers (p), and tall (T) is dominant over short (t). Determine the genotypes of the parents in the following cross: Pink, tall x pink, short O / pink, tall: /s pink, short: /s white, tall: / white, short Genotypes: () (ii) Phenotypes: Pink, tall Pink, short b. A woman has blood type A MM. She has a child with blood type O MN. Which of the following men could not be the child's father? Explain your reasoning. Man Blood type Peter O NN Rob AB MN Doug B MN Simon A NN Mike АВ Мarrow_forwardIN DROSOPHILA, AN X-LINKED RECESSIVE MUTATION, Xm CAUSES MINIATURE WINGS. LIST THE F₂ PHENOTYPIC RATIOS IF: A MINIATURE-WINGED FEMALE IS CROSSED WITH A NORMAL MALE AND A MINIATURE-WINGED MALE IS ● ● CROSSED WITH A NORMAL FEMALE. WHAT WOULD THE PHENOTYPIC RATIO FROM (A) BE IF THE MINIATURE- WINGED GENE WERE AUTOSOMAL? ASSUME IN ALL CASES THAT THE P1 INDIVIDUALS ARE TRUE-BREEDING.arrow_forwardDeranged: is a phenotype in Drosophila in which the thoracic bristles are disarranged and the wings held vertically upward. Crosses between deranged females and normal males, each from pure stock cultures, result in a 1:1 ratio of normal females to deranged males among the progeny. What does this show? A. The gene for deranged is autosomal and dominant. B. The gene for deranged is autosomal and recessive. C. The gene for deranged is X-linked and dominant. D. The gene for deranged is X-linked and recessive. E. Deranged is determined by two genes interacting epistatically.arrow_forward
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