Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 5, Problem 12P

In corn, the allele A allows the deposition of anthocyanin (blue) pigment in the kernels (seeds), while aa plants have yellow kernels. At a second gene, W– produces smooth kernels, while ww kernels are wrinkled. A plant with blue smooth kernels was crossed to a plant with yellow wrinkled kernels. The progeny consisted of 1447 blue smooth, 169 blue wrinkled, 186 yellow smooth, and 1510 yellow wrinkled.

a. Are the a and w loci linked? If so, how far apart are they?
b. What was the genotype of the blue smooth parent? Include the chromosome arrangement of alleles.
c. If a plant grown from a blue wrinkled progeny seed is crossed to a plant grown from a yellow smooth F seed, what kinds of kernels would be expected, and in what proportions?
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In roses, purple flower color is determined by the dominant P allele, while pp homozygotes are white. The presence of long stems is determined by the dominant S allele, while ss homozygotes have short stems. Both mutations are completely penetrant. A test cross was performed between a rose plant of unknown genotype with a white flowered, short stemmed rose plant (pp ss) and the following 200 progeny plants were obtained: 84 white flowers, long stems 16 purple flowers, long stems 82 purple flowers, short stems 18 white flowers, short stems Select the statements below that are TRUE. Select 2 correct answer(s) The P and S genes independently assort during meiosis. The map distance between P and S is 17 CM. The genotype of the progeny plants with purple flowers and short stems is PP ss. The map distance between P and S is 83 CM. The homologs in the plant with unknown genotype are p S and Ps. The homologs in the plant with unknown genotype are PS and p s.
The alleles his-5 and lys-1, found in yeast, result in cells that require histidine and lysine for growth, respectively.  A cross was made between two haploid yeast strains that are his-5 lys-1 and his+ lys+.  973 tetrads were analyzed, with the follow pattern:   7 tetrads with 2 his-5 lys+ spores and 2 his+ lys-1 spores 603 tetrads with 2 his-5 lys-1 spores and 2 his+ lys+ spores 363 tetrads with 1 his-5 lys-1 spore, 1 his-5 lys+ spore, 1 his+ lys-1 spores, and 1 his+ lys+ spore   Compute the map distance between these two genes using the method that considered double crossovers and the one that does not.  Which gives the higher value?  Why?   What is the frequency of single crossovers between these genes?  Explain.   Based on the frequency of single-crossovers, how many double crossovers would one expect?  Is positive interference occurring?
The alleles his-5 and lys-1, found in yeast, result in cells that require histidine and lysine for growth, respectively.  A cross was made between two haploid yeast strains that are his-5 lys-1 and his+ lys+.  973 tetrads were analyzed, with the follow pattern:   7 tetrads with 2 his-5 lys+ spores and 2 his+ lys-1 spores 603 tetrads with 2 his-5 lys-1 spores and 2 his+ lys+ spores 363 tetrads with 1 his-5 lys-1 spore, 1 his-5 lys+ spore, 1 his+ lys-1 spores, and 1 his+ lys+ spore   Compute the map distance between these two genes using the method that considered double crossovers and the one that does not.  Show your work.  Which give the higher value?  Why?   What is the frequency of single crossovers between these genes?  Explain.   Based on the frequency of single-crossovers, how many double crossovers would one expect?  Is positive interference occurring?

Chapter 5 Solutions

Genetics: From Genes to Genomes

Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a shows chromosomes during prophase of...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - Prob. 40PCh. 5 - Prob. 41PCh. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 43PCh. 5 - This problem leads you through the derivation of a...Ch. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - Prob. 46PCh. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Figure 5.29 shows mitotic recombination leading to...Ch. 5 - A diploid strain of yeast has a wild-type...Ch. 5 - In Drosophila, the yellow y gene is near the...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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