Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 5, Problem 42P

Indicate the percentage of tetrads that would have 0, 1, 2, 3, or 4 viable spores after Saccharomyces cerevisiae a / α diploids of the following genotypes are sporulated:

a. A true-breeding wild-type strain (with no mutations in any gene essential for viability).
b. A strain heterozygous for a null (completely inactivating) mutation in a single essential gene.
For the remaining parts of this problem, consider crosses between yeast strains of the form a   ×   b , where a and b are both temperature-sensitive mutations in different essential genes. The cross is conducted under permissive (low-temperature) conditions. Indicate the percentage of tetrads that would have 0, 1, 2, 3, or 4 viable spores subsequently measured under restrictive (high-temperature) conditions.
c. a and b are unlinked, and both are 0 m.u. from the centromere.
d. a and b are unlinked; a is 0 m.u. from the centromere, while b is 10 m.u. from the centromere.
e. a and b are 0 m.u. apart.
f. a and b are 10 m.u. apart. Assume all crossovers between a and b are SCOs (single crossovers).
g. In part (f), if a four-strand DCO (double crossover) occurred between a and b, how many of the spores in the resulting tetrad would be viable at high temperature?
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Chapter 5 Solutions

Genetics: From Genes to Genomes

Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a shows chromosomes during prophase of...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - Prob. 40PCh. 5 - Prob. 41PCh. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 43PCh. 5 - This problem leads you through the derivation of a...Ch. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - Prob. 46PCh. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Figure 5.29 shows mitotic recombination leading to...Ch. 5 - A diploid strain of yeast has a wild-type...Ch. 5 - In Drosophila, the yellow y gene is near the...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY